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Method for preparation of nasal washing liquid from herba andrographis extract product and derivative injection

An Andrographis paniculata and injection technology, applied in anti-inflammatory agents, drug delivery, antiviral agents, etc., can solve the problems of high clinical treatment cost, poor targeting of injection administration, poor patient compliance, etc., to promote wound healing, Good compliance and the effect of ensuring safety

Inactive Publication Date: 2016-06-22
哈药集团中药二厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problems of poor injection targeting, poor patient compliance, and high clinical treatment cost when the existing Andrographis paniculata extract and

Method used

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  • Method for preparation of nasal washing liquid from herba andrographis extract product and derivative injection
  • Method for preparation of nasal washing liquid from herba andrographis extract product and derivative injection
  • Method for preparation of nasal washing liquid from herba andrographis extract product and derivative injection

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specific Embodiment approach 1

[0015] Specific embodiment one: a kind of Andrographis paniculata extract and derivative injection of the present embodiment are prepared the preparation method of antiviral nasal washing solution according to the following steps:

[0016] 1. Weighing: Take 3 to 6 parts by mass of Andrographis paniculata extract or Andrographis paniculata extract derivative injection, 200 to 600 parts of glucose sodium chloride injection with a mass percentage of 5%, and 2 to 5 parts of Thickener;

[0017] 2. Dissolving auxiliary materials: add 100 to 300 parts of the thickener weighed in step 1 to 5% glucose sodium chloride injection by mass, fully shake and dissolve to form a gel solution to obtain a thickener gel solution;

[0018] 3. Dissolving Andrographis paniculata extract and derivative injection: dissolve or dilute the Andrographis paniculata injection preparation taken in step 1 into 5% glucose sodium chloride injection solution by mass percentage, shake and mix well;

[0019] 4. Pr...

specific Embodiment approach 2

[0022] Specific embodiment two: the difference between this embodiment and specific embodiment one is: get 2 to 5 parts of Andrographis paniculata extract or Andrographis paniculata extract derivative injection, 150 to 550 parts of 5% glucose sodium chloride described in step one Injection; weigh 1.5 to 4.5 parts of thickener. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0023] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is: in step one, take 1 to 4 parts of Andrographis paniculata extract or Andrographis paniculata extract derivative injection; 100 to 500 parts of mass percentage is 5% Glucose Sodium Chloride Injection and 1-4 parts of thickener. Others are the same as in the first or second embodiment.

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Abstract

The present invention discloses a method for preparation of a nasal washing liquid from herba andrographis extract product and derivative injections, relates to a method for preparation of the nasal washing liquid from a herba andrographis extract product injection and a herba andrographis extract product derivative injection, and aims to solve the problems of poor targeting ability and poor patient compliance when a herba andrographis injection in the prior art is used for clinical treatment of nasal diseases caused by rhinitis, bacterial viral infections and the like in the manner of injection administration. The method for preparation of the nasal washing liquid from the herba andrographis injections is as follows: 1, the herba andrographis extract product injection or the herba andrographis extract product derivative injection and other raw materials and auxiliary materials are taken; 2, the auxiliary materials are dissolved materials; 3, the herba andrographis injections are dissolved and diluted; and 4, solutions of the dissolved auxiliary materials and the dissolved herba andrographis injections are mixed and shaken well to obtain the nasal washing liquid. The prepared injection herba andrographis extract product and injection herba andrographis extract product derivative nasal washing liquid is safe, efficient, economical, simple and easy to use, and the method is suitable for on-site preparation in houses and workplaces. The method is used in the fields of treatment of upper respiratory tract infection, colds, rhinitis and the like.

Description

technical field [0001] The invention relates to a preparation method of nasal washing solution for treating upper respiratory tract infection, cold, rhinitis and the like. Background technique [0002] The traditional Chinese medicine Andrographis paniculata contains many active ingredients. Modern medical science has fully purified the active ingredients of Andrographis paniculata, or added groups or compounded salts to the extracts, and produced many products about Andrographis paniculata extracts and derivatives, including effective The ingredients are andrographolide, andrographolide salt, dehydroandrographolide, dehydroandrographolide succinate half ester salt, andrographolide flavonoids and other injections with antipyretic, antibacterial, antiviral, and immune-enhancing effects, used for the treatment of Rhinitis, bacterial infection, viral infection, cold and fever, upper respiratory tract infection and other diseases have a wide range of clinical application value. ...

Claims

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Application Information

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IPC IPC(8): A61K36/19A61K9/08A61P11/02A61P31/12A61P29/00A61P37/04
Inventor 刘景国柳松林钮旭升裴福成尹涛郑玥李文军肇静静单钰毓谢明李殿明王英新张丽君江治武
Owner 哈药集团中药二厂
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