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Traditional Chinese medicine composition with effects of stopping cough and relieving asthma and preparation method of traditional Chinese medicine composition

A composition and technology of traditional Chinese medicine, applied in the field of modernization of traditional Chinese medicine, can solve problems such as complicated preparation methods and increased difficulty in quality control, and achieve improved curative effect, stable and controllable quality, and excellent phlegm-reducing effects

Inactive Publication Date: 2016-07-13
津药达仁堂集团股份有限公司乐仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The curative effect of Zhisou Dingchuan Oral Liquid is remarkable, but the preparation method is more complicated, and the pH value is adjusted twice, which increases the difficulty of quality control

Method used

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  • Traditional Chinese medicine composition with effects of stopping cough and relieving asthma and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition with effects of stopping cough and relieving asthma and preparation method of traditional Chinese medicine composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: preparation of Chinese medicine extract

[0022] 1. Prescription:

[0023] Ephedra 100g Bitter almond 100g Licorice 100g Gypsum 100g

[0024] Two. Preparation method:

[0025] Weigh each raw material according to the ratio of raw materials, and set aside; crush bitter almonds into coarse powder, remove oil, extract twice with 70% ethanol by volume percentage, extract 6 times the amount for 1.5 hours for the first time, and extract 4 times the amount for the second time Extract for 1 hour, combine the extracts, concentrate until the relative density is 1.20 under the condition of 50-60°C, and obtain the concentrated solution A; ephedra, licorice, and gypsum are extracted twice in water, the first extraction is 8 times the amount for 2 hours, and the second extraction is 6 Extract multiple times for 1.5 hours, combine the extracts, concentrate to a relative density of 1.25 at 50-60°C, and obtain a concentrated solution B; mix the concentrated solutions A a...

Embodiment 2

[0026] Embodiment 2: preparation of Chinese medicine extract

[0027] 1. Prescription:

[0028] Ephedra 500g Bitter almond 500g Licorice 500g Gypsum 500g

[0029] Two. Preparation method:

[0030] Weigh each raw material according to the ratio of raw materials, and set aside; the bitter almonds are crushed into coarse powder, degreased, and extracted twice with 85% ethanol with a volume percentage concentration of 6 times for 1.5 hours for the first time, and 4 times for the second time. For 1 hour, combine the extracts and concentrate until the relative density is 1.15 at 50-60°C to obtain concentrated solution A; water extraction of ephedra, licorice, and gypsum is performed twice, the first extraction is 10 times the amount for 2 hours, and the second extraction is 8 times Quantitative extraction for 1 hour, combined extracts, concentrated to a relative density of 1.25 under the condition of 50-60°C to obtain concentrated solution B; mixed concentrated solutions A and B, ...

Embodiment 3

[0031] Embodiment 3: preparation of Chinese medicine extract

[0032] 1. Prescription:

[0033] Ephedra 500g Bitter almond 500g Licorice 500g Gypsum 500g

[0034] Two. Preparation method:

[0035] Weigh each raw material according to the ratio of raw materials, set aside; crush bitter almonds into coarse powder, remove oil, extract 3 times with 60% ethanol with 2-8 times the volume percentage concentration, each time for 1 hour, combine the extracts, concentrate The relative density is 1.30 under the condition of 50-60°C, and the concentrated solution A is obtained; the ephedra, licorice, and gypsum are extracted with 4 times of water for 3 times, each time for 3 hours, the extracts are combined, and concentrated to the relative density under the condition of 50-60°C The concentration is 1.35, and the concentrated solution B is obtained; the concentrated solution A and B are mixed and dried to obtain the dried product I; the dried product I is the active ingredient.

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Abstract

The invention discloses a traditional Chinese medicine composition with effects of stopping cough and relieving asthma and a preparation method of the traditional Chinese medicine composition, and belongs to the field of modernization of traditional Chinese medicines.The effective constituent of the traditional Chinese medicine composition with effects of stopping cough and relieving asthma is prepared from the following raw materials in parts by weight: 1 part of Herba Ephedrae, 1 part of Semen Armeniacae Amarum, 1 part of Radix Glycyrrhizae and 1 part of Gypsum Fibrosum.The traditional Chinese medicine composition has the advantages that the quality is stable and controllable, the curative effect of the traditional Chinese medicine composition is remarkably higher than that of an existing commercially available dosage form, the taking dosage of a patient is reduced, bioavailability is improved, and economic and social benefits are remarkable.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for relieving cough and relieving asthma and a preparation method thereof, belonging to the field of traditional Chinese medicine modernization. Background technique [0002] Zhisou Dingchuan Oral Liquid is a commercially available traditional Chinese medicine for relieving cough and relieving asthma. Its prescription is 1000g ephedra, 1000g bitter almond, 1000g licorice, and 1000g gypsum. The oral liquid has the functions of pungent and cool catharsis, clearing lung and relieving asthma. For external cold and internal heat, body heat and thirst, cough with excessive phlegm, shortness of breath, chest and diaphragm fullness; acute bronchitis with the above syndromes. [0003] The preparation method of Zhisou Dingchuan oral liquid is as follows: the above four flavors, except bitter almond, the other three flavors such as gypsum are decocted twice, each time for 1.5 hours, combined dec...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61P11/00A61P11/14A61P11/06A61K33/06
Inventor 王磊闫晓楠孙琳耿彤张宇王玉晶
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
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