Probiotic fermented traditional Chinese medicine composition for treating gastric cancer and preparation method and application thereof

A composition and technology of probiotics, applied in the field of traditional Chinese medicine, can solve the problems of low utilization rate of raw materials, pain of patients, poor taste, etc., and achieve the effect of improving utilization rate, improving quality of life, and quick results

Active Publication Date: 2016-07-13
SANZHU FUER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are many domestic patents related to the treatment of gastric cancer with traditional Chinese medicine compound prescriptions, such as the Chinese medicine preparation for the prevention and treatment of gastric cancer and its preparation method-CN201310543123, the Chinese medicine preparation for the treatment of gastric cancer and its preparation method-CN200710052851, a Chinese medicine combination for the treatment of gastric cancer Material-CN201110262095, a traditional Chinese medicine composition for treating gastric cancer-CN201210416744, a traditional Chinese medicine oral decoction for treating gastric cancer-CN201010003136, a traditional Chinese medicine composition for treating gastric cancer and its preparation method-CN201310017007, a traditional Chinese medicine for treating gastric cancer and its preparation method Preparation method-CN201210582510, etc. Most of the above inventions are classic prescriptions and proven prescriptions, and the production methods are simple and extensive, such as decoctions, pills, powders, capsules, etc. Although they have certain curative effects, the utilization rate of raw materials is low, the taste is extremely poor, and the effect is slow , causing great pain to patients when taken for a long time

Method used

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  • Probiotic fermented traditional Chinese medicine composition for treating gastric cancer and preparation method and application thereof
  • Probiotic fermented traditional Chinese medicine composition for treating gastric cancer and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0035] Example 1: Preparation of probiotic fermented Chinese medicine composition A for the treatment of gastric cancer

[0036] It is made of the following medicinal materials in parts by weight: 3 parts of American ginseng, 4 parts of Bupleurum, 4 parts of Citrus aurantii, 4 parts of Scutellaria baicalensis, 4 parts of Pinellia chinensis, 8 parts of Shijianchuan, 10 parts of seaweed, 4 parts of Fritillaria, 8 parts of Radix Paeoniae Alba, 4 parts of Rhizoma Chuanxiong, 4 parts of Cyperus cyperi, 3 parts of Galangal, 7 parts of Chinese Angelica, 7 parts of Cistanche, 2 parts of Roasted Glycyrrhiza. The specific preparation method is as follows:

[0037] (1) Medicinal material treatment: Scutellaria baicalensis and Shi Jianchuan are added together with 8 times the amount of medicinal materials in water, soaked for 30 minutes, extracted with high-pressure water at 115°C for 60 minutes, filtered, and the filtrate is sterilized at 115°C for 60 minutes to be sterile. Scutellaria b...

Embodiment 2

[0042] Example 2: Preparation of probiotic fermented Chinese medicine composition B for the treatment of gastric cancer

[0043] It is made of the following medicinal materials in parts by weight: 3 parts of American ginseng, 7 parts of Bupleurum, 7 parts of Citrus aurantii, 4 parts of Scutellaria baicalensis, 6 parts of Pinellia chinensis, 15 parts of Shijianchuan, 12 parts of seaweed, 4 parts of Fritillaria, 9 parts of Radix Paeoniae Alba, 5 parts of Rhizoma Chuanxiong, 6 parts of Cyperus cyperi, 5 parts of Galangal, 6 parts of Chinese Angelica, 8 parts of Herba Cistanche, 2 parts of Roasted Glycyrrhiza. The specific preparation method is as follows:

[0044] (1) Treatment of medicinal materials: Scutellaria baicalensis and Shi Jianchuan are added together with 10 times the amount of medicinal materials in water, soaked for 60 minutes, extracted with high-pressure water at 115°C for 50 minutes, filtered, and the filtrate is sterilized at 121°C for 30 minutes to be sterile. S...

Embodiment 3

[0049] Example 3: Preparation of probiotic fermented Chinese medicine composition C for the treatment of gastric cancer

[0050] It is made of the following medicinal materials in parts by weight: 3 parts of American ginseng, 6 parts of Bupleurum, 6 parts of Citrus aurantii, 6 parts of Scutellaria baicalensis, 5 parts of Pinellia chinensis, 12 parts of Shijianchuan, 10 parts of seaweed, 4 parts of Fritillaria, 9 parts of Radix Paeoniae Alba, 5 parts of Rhizoma Chuanxiong, 6 parts of Cyperus cyperi, 4 parts of Galangal, 9 parts of Angelica sinensis, 10 parts of Herba Cistanche, 2 parts of Roasted Glycyrrhiza. The specific preparation method is as follows:

[0051] (1) Medicinal material treatment: Scutellaria baicalensis and Shi Jianchuan are added together with 12 times the amount of medicinal materials in water, soaked for 60 minutes, extracted with high-pressure water at 115°C for 60 minutes, filtered, and the filtrate is sterilized at 115°C for 50 minutes for later use to ob...

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Abstract

The invention discloses a probiotic fermented traditional Chinese medicine composition for treating a gastric cancer and a preparation method and application thereof.The fermented traditional Chinese medicine composition is prepared through the steps that extraction and enzymolysis are performed on radix panacis quinquefolii, radix bupleuri, fructus aurantii, radix scutellariae, rhizoma pinelliae, herba salviae chinensis, cuttle bones, bulbus fritillariae thunbergii, radix paeoniae alba, rhizoma chuanxiong, rhizoma cyperi processed with vinegar, rhizoma galangae, radix angelica sinensis, herba cistanche and prepared liquorice roots, fructose, peptone, yeast cream, yeast powder, inorganic salt, a sweetening agent and the like are added, probiotic fermentation is performed, and then dietary fiber and prebiotics are added.The probiotic fermented traditional Chinese medicine composition has the effects of inhibiting gastric cancer cell growth, improving the immunity, regulating the intestinal flora balance, improving the gastrointestinal function and the like and is capable of rapidly achieving the effects and good in mouthfeel and treatment effect.Experiments show that the fermented composition can significantly increase the quantity of mouse T lymphocytes and improve the organism immunity, the inhibition ratio on gastric cancer cells can reach 65%, and therefore the fermented composition is good in treatment effect on the gastric cancer.

Description

technical field [0001] The invention relates to a probiotic fermented traditional Chinese medicinal composition for treating gastric cancer and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Gastric cancer is one of the most common malignant tumors in the world. In my country, its incidence rate ranks first among all kinds of tumors. About 170,000 people die from gastric cancer every year, which is nearly 1 / 4 of all malignant tumor deaths. More than 10,000 new gastric cancer patients are produced. Gastric cancer is indeed a disease that seriously threatens the health of the people. Gastric cancer can occur at any age, but it is more common in 40-60 years old, and there are more men than women, about 2:1. Gastric cancer can occur in any part of the stomach, but it is more common in the gastric antrum, especially the lesser curvature of the stomach. Untreated life expectancy is about 13 months. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P35/00A61K35/618
Inventor 吴炳新陆继臣孙筱林牛纪江褚新红
Owner SANZHU FUER PHARMA
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