Tracheal stent, tissue engineering trachea adopting tracheal stent and application of tracheal stent and tissue engineering trachea

A tracheal stent and tissue engineering technology, applied in the field of medical devices, can solve problems such as low success rate and achieve the effect of good support ability

Inactive Publication Date: 2016-08-17
SHANGHAI CHILDRENS MEDICAL CENT AFFILIATED TO SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In view of the anatomical and physiological characteristics of the trachea, it is still a severe challenge to construct a long segment of tissue-engineered trachea with complete structure and function, and the success rate is extremely low

Method used

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  • Tracheal stent, tissue engineering trachea adopting tracheal stent and application of tracheal stent and tissue engineering trachea

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Embodiment Construction

[0025] The tracheal stent provided by the present invention, the tissue engineered trachea using the tracheal stent and the specific implementation of the application thereof will be described in detail below in conjunction with the accompanying drawings. The accompanying drawing is only a schematic diagram of the structure of the tracheal stent of the present invention, not an actual structural diagram of the tracheal stent.

[0026] see figure 1 The trachea stent of the present invention includes a plurality of support rings 2 arranged at intervals, and a hollow mesh support member 1 is arranged between adjacent support rings 2 to form a structure similar to a trachea.

[0027] The trachea-like structure means that the shape of the trachea stent is the same or similar to that of a normal trachea of ​​a human body. The design of the tracheal stent in this shape can effectively connect the upper and lower ends of the stenotic trachea, fully simulate the normal trachea, and fa...

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Abstract

The invention provides a tracheal stent, a tissue engineering trachea adopting the tracheal stent and application of the tracheal stent and tissue engineering trachea. The tracheal stent comprises a plurality of supporting rings which are arranged at intervals, wherein a hollow reticular supporting part is arranged between adjacent supporting rings. The tracheal stent has the advantages of excellent supporting capacity, relatively good cartilage which is identified by a dyeing means can be formed within two weeks and can be directly used for transplanting, while the stent reported in the prior art can be transplanted for at least two months generally; and the tracheal stent in the prior art is cultured in vitro firstly, subcutaneously pre-transplanted on animals and then is taken out for transplanting, but the cartilage formed by virtue of the tracheal stent within two weeks can be transplanted without animal subcutaneous pre-transplanting.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a trachea stent, a tissue engineered trachea using the trachea stent and applications thereof. Background technique [0002] Clinically, the incidence rate of tracheal malformation in children with congenital heart disease (CHD) is relatively high, and literature reports can account for about 12.9% of children with CHD. In my country, the incidence rate of congenital heart disease is about 0.7-0.8%, and about 150,000 new children are born every year. In the Heart Center of Shanghai Children's Medical Center, many children with congenital heart disease are complicated with tracheal malformation every year. Tracheal stenosis is the most common type of malformation of the trachea, and one of the causes is compression and softening of the trachea due to cardiovascular malformations. The treatment of tracheal stenosis in infants and young children is still a clinical problem. At prese...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/04B33Y80/00
CPCA61F2/04A61F2002/046A61F2240/001B33Y80/00
Inventor 付炜
Owner SHANGHAI CHILDRENS MEDICAL CENT AFFILIATED TO SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE
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