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External use type adnate elder herb ointment for treating impact injuries and sprains and preparing method thereof

A technology for bruises, sprains, and blood-filled grass, which is applied in the field of natural plant extraction and medical application, can solve the problems of inconvenient storage, carrying and transportation, short residence time of medicinal wine, and inconvenient use, and achieves a goal suitable for large-scale industrial production and good quality. Stability and appearance properties, the effect of improving the effect of action

Inactive Publication Date: 2016-09-21
YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The traditional method of using Xuemancao for treatment is to make Xuemancao medicinal wine liniment and wipe the outside. However, Xuemancao medicinal wine liniment is liquid, has low viscosity and high fluidity, which is not easy to store, carry and transport. It is easy to contact mucous membranes such as eyes and mouth, causing strong local irritation; when using medicinal wine to wipe, the medicinal wine stays in the diseased area for a short time, which also affects the efficacy of the effect
In view of the shortcomings of Xueman herbal wine, such as inconvenient use and easy contamination of clothes, in order to inherit and better utilize the use value of Xueman herbal wine, enhance the curative effect, overcome the inconvenient use of the original dosage form, and enhance the effect of the drug, it is necessary to Improve the original dosage form and preparation method

Method used

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  • External use type adnate elder herb ointment for treating impact injuries and sprains and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A preparation process of Xuemancao external ointment for treating bruises and sprains, comprising the steps of:

[0021] S1. Preparation of Herba Cerulea Extract: Take 250g of the above-ground part of Herba Cauliflower, crush it into 100-200 mesh, add 2500ml of water, prepare the Herba Cerulean Extract by microwave extraction method, soak at 80°C for 1 hour, and filter to obtain the filtrate The filter residue is repeatedly extracted four times by the above-mentioned method, and the combined filtrate is concentrated to 450ml to obtain an extract whose crude drug concentration is 0.55g / ml;

[0022] S2. Preparation of matrix: Accurately weigh 245g of petrolatum, 160g of cetyl alcohol, 10g of sodium lauryl sulfate, 160g of glycerin, and 1.5g of ethylparaben. Under stirring conditions, mix and disperse the raw materials of each matrix, and heat to 70°C, filter, cool to 38-40°C, set aside;

[0023] S3. Preparation of ointment: Take 0.5g of the Herba Crimson extract obtained...

Embodiment 2

[0025] A preparation process of Xuemancao external ointment for treating bruises and sprains, comprising the steps of:

[0026] S1. Preparation of Herba Cerulea Extract: Take 250g of the aboveground part of Herba Cerulea, crush it into 100-200 mesh, add 1250ml of hydrous ethanol, and prepare the Herba Cerulea Extract by solvent reflux method, soak at 80°C for 1 hour, and filter , to obtain the filtrate; the filter residue was repeatedly extracted four times by the above-mentioned method, the combined filtrate was concentrated to 450ml, and the crude drug concentration was obtained to be an extract of 0.55g / ml;

[0027] S2. Preparation of matrix: Accurately weigh 200g of petrolatum, 125g of cetyl alcohol, 5g of sodium lauryl sulfate, 142.5g of glycerin, and 2.5g of ethylparaben. Under stirring conditions, mix and disperse the raw materials of each matrix, and heat to 70°C, filter, cool to 38-40°C, and set aside;

[0028] S3. Preparation of ointment: Take 5 g of the Herba Cerem...

Embodiment 3

[0030] A preparation process of Xuemancao external ointment for treating bruises and sprains, comprising the steps of:

[0031] S1. Preparation of Herba Cerulea Extract: Take 250g of Herba Cauliflower aerial part, crush it into 100-200 mesh, add 5000ml of ethanol, use ultrasonic extraction method to prepare Herba Cerulean Extract, soak at 80°C for 1h, filter, Obtain the filtrate; the filter residue is repeatedly extracted five times by the above method, the combined filtrate is concentrated to 450ml, and the crude drug concentration is obtained as an extract of 0.55g / ml;

[0032] S2. Preparation of matrix: Accurately weigh 225g of petrolatum, 125g of cetyl alcohol, 10g of sodium lauryl sulfate, 139.5g of glycerin, and 0.5g of ethylparaben. Under stirring conditions, mix and disperse the raw materials of each matrix, and heat to 70°C, filter, cool to 38-40°C, and set aside;

[0033] S3. Preparation of ointment: Take 25g of the Herba Crimson extract obtained in step S1 and 75g ...

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Abstract

The invention relates to the fields of natural plant extraction and medicine application, in particular to an external use type adnate elder herb ointment for treating impact injuries and sprains and a preparing method thereof. The external use type adnate elder herb ointment is prepared from, by mass, 0.5-25 wt% of adnate elder herb extract and the balance matrix components. The external use type adnate elder herb ointment is safe and convenient to use and carry, definite in effect and easy to prepare.

Description

technical field [0001] The invention relates to the field of natural plant extraction and medical application, in particular to a Xuemancao external ointment for treating bruises and sprains, and a preparation method thereof. Background technique [0002] Ointment is a type of external dosage form commonly used clinically for anti-inflammatory and analgesic treatment for bruises, sprains, muscle pain, joint pain, fracture pain and other diseases. Blood Mancao is a plant of the genus Elderberry in the Lonicera family, widely distributed in Yunnan, Sichuan, Guangxi, Guizhou and other places. The medicinal value of Xueman herb is very high, because it has the effects of promoting blood circulation and promoting qi, removing blood stasis and dredging collaterals, dredging numbness and relieving pain, it is often used by Yi, Dai, Tibetan, Hani and other ethnic minorities to treat rheumatic bone pain, bruises, sprains, Arthritis, fractures and other diseases, the curative effect ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/35A61K9/06A61K47/06A61P29/00
CPCA61K36/35A61K9/0014A61K9/06A61K47/06A61K2236/331A61K2236/333
Inventor 李维熙王葳王文静殷华刘冬丽陈飞龙谢世猛黎勇坤
Owner YUNNAN UNIV OF TRADITIONAL CHINESE MEDICINE
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