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Heart nourishing and nerve soothing composition and preparation method thereof

A technology of nourishing the mind and calming the nerves and composition, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., and can solve problems such as obvious side effects, affecting the mental state, affecting normal work and life, etc.

Inactive Publication Date: 2016-10-12
GUOYAOJITUAN TONGJITANG (GUIZHOU) PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The effect is good, but its side effects are also obvious, which is mainly reflected in affecting the mental state on the second day after taking the medicine, thereby further
[0004] One step affects normal work and life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] prescription: 1425 grams of fried jujube kernels, 285 grams of salvia miltiorrhiza, 285 grams of vinegar schisandra

[0031] Preparation:

[0032] (1) Suanzaoren, extract with water for 3 times, combine the extracts, concentrate to a clear paste with a relative density of 1.40, add an equal amount of water, let it stand still, take the supernatant, put it on a styrene-type macroporous adsorption resin, and wash with water (5-8BV), discard the water eluate, continue to elute with 65% ethanol 4-6BV, collect the eluate, dry to dryness under reduced pressure, and pulverize into fine powder to obtain the jujube seed water extract;

[0033] (2) Salvia miltiorrhiza, extracted 3 times with water, combined the extracts, concentrated to a clear paste with a relative density of 1.40, filtered, and the filtrate was washed with water (2-5 BV) by a macroporous adsorption resin (HPD450, D101, AB8 or HPD600), discarded The water eluate was continued to be eluted with 5 times the a...

Embodiment 2

[0038] Prescription: 1140 grams of fried jujube kernels, 228 grams of salvia miltiorrhiza, 228 grams of vinegar schisandra

[0039] Preparation:

[0040] (1) Suanzaoren, extract with water once, combine the extracts, concentrate to a clear paste with a relative density of 1.35, add an equal amount of water, let it stand still, take the supernatant, put it on a styrene-type macroporous adsorption resin, and wash with water (5-8BV), discard the water eluate, continue to elute with 50% ethanol 4-6BV, collect the eluate, dry to dryness under reduced pressure, and pulverize into fine powder to obtain the jujube seed water extract;

[0041] (2) Danshen, extract with water once, combine the extracts, concentrate to a clear paste with a relative density of 1.35-1.45, filter, and wash the filtrate with water (2-5 BV) with macroporous adsorption resin (HPD450, D101, AB8 or HPD600), Discard the water eluate, continue to elute with 6-10 times of 40% ethanol, collect the eluate, dry to dr...

Embodiment 3

[0046] prescription: 1710 grams of fried jujube kernels, 342 grams of salvia miltiorrhiza, 342 grams of vinegar schisandra

[0047] Preparation:

[0048] (1) Suanzaoren, extract with water 5 times, combine the extracts, concentrate to a clear paste with a relative density of 1.45, add an equal amount of water, let it stand, take the supernatant, put it on a styrene-type macroporous adsorption resin, and wash with water (5-8BV), discard the water eluate, continue to elute with 80% ethanol 4-6BV, collect the eluate, dry to dryness under reduced pressure, and pulverize into fine powder to obtain the jujube seed water extract;

[0049] (2) Danshen, extract with water 5 times, combine the extracts, concentrate to a clear paste with a relative density of 1.45, filter, and wash the filtrate with water (2-5 BV) with macroporous adsorption resin (HPD450, D101, AB8 or HPD600), discard The water eluate was continued to be eluted with 10 times of 60% ethanol, the eluate was collected...

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PUM

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Abstract

The invention discloses a heart nourishing and nerve soothing composition and a preparation method thereof. The heart nourishing and nerve soothing composition is prepared from fried semen ziziphi spinosae, salvia miltiorrhiza, vinegar-prepared schisandra chinensis and appropriate amounts of auxiliary materials. The preparation method comprises the following steps: extracting semen ziziphi spinosae and salvia miltiorrhiza with water respectively, conducting adsorption elution with macroporous adsorption resin to obtain a semen ziziphi spinosae extract and a salvia miltiorrhiza extract, conducting supercritical extraction on schisandra chinensis to obtain a schisandra chinensis lignan extract, mixing the extracts uniformly, adding starch, uniformly mixing, preparing granules from the mixture, smashing, drying and encapsulating to obtain the heart nourishing and nerve soothing composition. According to the heart nourishing and nerve soothing composition and the preparation method thereof, a resin elution process is adopted, so that obtained capsules have less impurities.

Description

Technical field [0001] The present invention involves a composition and preparation method of nourishing the heart. Background technique [0002] Insomnia is a common condition. For the treatment of insomnia, although anti -psychiatric sedation drugs are used [0003] The effect is good, but its side effects are also obvious. [0004] One step affects normal work and life.Traditional Chinese medicine jujube and soothing agent, replenish the mind, use it for insomnia, dizziness, [0005] forgetful.Jujiao Ren'an Divine Divine Division is compatible with jujube kernels, Salva and Schisandra Sanwei. [0006] The acid and sweetness are flat, the main enters the heart and liver meridian, which can nourish the heart and live the liver, nourish the blood and safe, and to treat the medicine for the treatment of blood deficiency and irritability. [0007] It is for Jun medicine.Salva is bitter and cold, and the Lord enters the heart liver meridian. [0008] minister.Schisandra is sour and ...

Claims

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Application Information

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IPC IPC(8): A61K36/725A61K36/79A61K9/48A61P25/20
CPCA61K36/725A61K9/1652A61K36/537A61K36/57A61K36/79A61K2236/331A61K2236/37A61K2236/39A61K2236/51A61K2236/53
Inventor 周宁王晓春林必芬白志文其他发明人请求不公开姓名
Owner GUOYAOJITUAN TONGJITANG (GUIZHOU) PHARMA CO LTD