Spica prunellae granules and preparation method thereof

A technology of Prunella vulgaris and granules, which is applied in the field of Prunella vulgaris granules and its preparation, can solve the problems of ineffective autoimmune process, great influence on liver and kidney, and large side effects, so as to improve the quality of life, increase the extraction rate, and reduce toxicity. Effect with few side effects

Active Publication Date: 2016-11-09
山东仙河药业有限公司
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, restricting iodine intake, thyroid preparations, thyroxine, and immunomodulatory drugs are often used for treatment. Most patients need to take hormones for life, which has relatively large side effects, and has no effect on the body's autoimmune process, and the curative effect is poor. Hypocalcemia and other sequelae often occur with radioactive iodine therapy
Prunella vulgaris has a certain curative effect on lymphatic goiter, but long-term use of existing Prunella vulgaris granules has a greater impact on liver and kidney

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Spica prunellae granules and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A Prunella vulgaris granule, the prescription is: 400 parts of Prunella vulgaris, 62 parts of honeysuckle, 50 parts of Viola radix, 10 parts of Sophora flavescens, 72 parts of geranium seeds, 72 parts of lettuce, 12 parts of schisandra, and 10 parts of onion , 11 parts of yam powder;

[0026] The preparation method is as follows:

[0027] (1) Prunella vulgaris, honeysuckle, Viola chinensis, Sophora flavescens, geranium seed, lettuce and schisandra are coarsely crushed to obtain mixed medicinal materials, and 50-70% acetic acid containing 0.5-1.0% acetic acid is added to 12 times of the mixed medicinal materials. % ethanol aqueous solution, reflux extraction at 80°C for 2 times, each time for 1h, filter to obtain the filtrate, add 12 times the amount of water to the mixed medicinal materials for the dregs, heat and boil for 1 hour, filter to obtain the filtrate; combine the two filtrates, and concentrate to obtain The relative density is 1.2-1.3 thick paste (measured at...

Embodiment 2

[0032] A Prunella vulgaris granule, the composition of which is: 425 parts of Prunella vulgaris, 80 parts of honeysuckle, 45 parts of Viola chinensis, 17 parts of Sophora flavescens, 65 parts of geranium seeds, 65 parts of lettuce, 13 parts of schisandra, and 8 parts of onion , 10 parts of yam powder;

[0033] The preparation method is the same as in Example 1.

Embodiment 3

[0035] A Prunella vulgaris granule, the composition of which is: 448 parts of Prunella vulgaris, 70 parts of honeysuckle, 30 parts of Viola chinensis, 20 parts of Sophora flavescens, 55 parts of geranium, 55 parts of lettuce, 14 parts of schisandra, and 9 parts of onion , 12 parts of yam powder;

[0036] The preparation method is the same as in Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the technical field of a traditional Chinese medicinal preparation, and in particular relates to spica prunellae granules and a preparation method thereof. The granules are prepared from the following raw materials in parts by weight: 400-500 parts of spica prunellae, 50-80 parts of honeysuckle flowers, 30-60 parts of herba violae, 10-30 parts of radix sophorae flavescentis, 50-80 parts of radix semiaquilegiae, 50-80 parts of field sowthistle herb and 12-15 parts of fruits of Chinese magnoliavine. The spica prunellae granules provided by the invention can be used for curing lymphatic goiter, and the spica prunellae granules are high in cure rate and low in toxic and side effects and are capable of improving life quality of patients; different treatment methods are selected in accordance with different raw materials, so as to improve the extraction rate of active ingredients and avoid loss in an extracting process; and the prepared granules are convenient to drink and are applicable to industrial production.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a Prunella vulgaris granule and a preparation method thereof. Background technique [0002] Prunella vulgaris L., a perennial herb, has the effects of clearing heat and purging fire, improving eyesight, dispelling stagnation and reducing swelling. [0003] Lymphatic goiter is an autoimmune disease, more common in women, mainly manifested as goiter, most of which are diffuse, a few can be localized, and can be complicated by other immune diseases. Clinically, restricting iodine intake, thyroid preparations, thyroxine, and immunomodulatory drugs are often used for treatment. Most patients need to take hormones for life, which has relatively large side effects, and has no effect on the body's autoimmune process, and the curative effect is poor. Hypocalcemia and other sequelae often occur with radioactive iodine therapy. Prunella vulgar...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61K9/16A61P5/14A61P37/02A61P1/16
CPCA61K9/1652A61K36/28A61K36/355A61K36/489A61K36/536A61K36/57A61K36/71A61K36/79A61K36/86A61K36/8945A61K36/8962A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 赵珂刘维利李鹏刘丽徐静于建李爱华
Owner 山东仙河药业有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products