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Transmission-type optical detection device for intelligent expiration molecular diagnosis system

A technology of molecular diagnosis and optical detection, applied in the direction of color/spectral characteristic measurement, etc., can solve problems such as poor specificity, inability to widely use instruments, and inability to fully meet clinical needs, and achieve high reliability results

Pending Publication Date: 2017-01-25
苏州一呼医疗科技有限公司
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  • Abstract
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Problems solved by technology

[0006] Current breath analysis instruments still mainly rely on large and expensive instruments, such as gas chromatography (GC) and mass spectrometer (MS), making these instruments not widely used
[0007] Other respiratory analysis instruments are detection devices made of electrochemical detection principles. Although they are small in size, they cannot fully meet the clinical needs due to limitations such as continuous dynamic monitoring of biomarkers, high detection costs, and poor specificity.

Method used

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  • Transmission-type optical detection device for intelligent expiration molecular diagnosis system
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  • Transmission-type optical detection device for intelligent expiration molecular diagnosis system

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Embodiment Construction

[0025] Such as Figure 1 to Figure 3 As shown, a transmission optical detection device of an intelligent exhalation molecular diagnosis system according to the present invention is used to detect the content of biomarkers in the exhaled air of a human body. The transmission optical detection device of the intelligent exhalation molecular diagnosis system includes a reaction pool 100, a biosensor 200 and an optical path structure for spectral analysis.

[0026] The biomarkers mentioned herein refer to the compounds in the exhaled breath of the human body, which are generally recognized clinically and used for the diagnosis of diseases. Exhaled compounds or breath molecules such as nitric oxide, carbon monoxide, hydrogen, methane, ammonia, aldehydes, and sulfides.

[0027] The biosensor 200 includes a reactant 201 and a matrix 202 capable of reacting with and absorbing biomarkers. The reaction body 201 has a sheet structure, and a plurality of reaction bodies 201 are mounted o...

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Abstract

The invention relates to a transmission-type optical detection device for an intelligent expiration molecular diagnosis system. The detection device comprises a reaction tank, a biologic sensor and a light path structure for spectral analysis, wherein the biologic sensor comprises a reactant which can react with and absorb a biomarker exhaled by a human body; a reaction chamber is arranged in the reaction tank; the reaction chamber is communicated with an external human exhaled air source; the biologic sensor is arranged in the reaction chamber and the reactant is packaged in the reaction chamber; the light path structure can generate light beam and inject into the reaction chamber; after the light beam passes by the reactant, the light beam is emitted out from the reaction tank, so as to form an absorption spectrum of the reactant. The transmission-type optical detection device for the intelligent expiration molecular diagnosis system adopts the reactant of the biologic sensor for reacting with the biomarker exhaled by the human body, the light path structure for performing spectral analysis on the reactant is adopted for detecting the reactant after absorbing the biomarker, the content of the biomarker exhaled by the human body can be quickly and accurately detected and the precision is high.

Description

technical field [0001] The invention belongs to the field of exhalation molecular diagnosis, in particular to a detection device of an exhalation molecular diagnosis system for detecting biomarkers in human exhalation. Background technique [0002] In addition to nitrogen, oxygen and carbon dioxide, the gas exhaled by a normal human body also contains many other compounds. Diseases can be diagnosed by detecting the content of these compounds. [0003] A study released by the Swiss Federal Institute of Technology in Zurich recently showed that the compounds exhaled by each person when they breathe are as unique as human fingerprints, and doctors can even diagnose diseases based on these compounds. At the same time, because the breath test method can also obtain similar results to urine tests and blood tests, it can not only be used to diagnose diseases in the future, but may also be used in athlete doping testing. The research results have been published in the international...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/31
CPCG01N21/31
Inventor 陈帆青鄢雨
Owner 苏州一呼医疗科技有限公司
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