Control method and device of serinus mozambicus mozambicus extract extraction technology

A control method and technology of a control device, which are applied in separation methods, solvent extraction, solid solvent extraction and other directions, can solve the problem that the extraction effect is affected, the parameters closely related to quality cannot be effectively controlled, and the stability of Jinqing extract is affected. and other problems to achieve the effect of uniform distribution and improved stability

Active Publication Date: 2017-02-01
JIANGSU KANION PHARMA CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional reverse extraction method is through manual control, the extraction effect is affected by the proficiency of manual operation, and the parameters closely related to the quality cannot be effectively controlled, which seriously affects the stability of the extraction process of Jinqing extract and the quality of the product

Method used

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  • Control method and device of serinus mozambicus mozambicus extract extraction technology
  • Control method and device of serinus mozambicus mozambicus extract extraction technology
  • Control method and device of serinus mozambicus mozambicus extract extraction technology

Examples

Experimental program
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Effect test

Embodiment 1

[0049] Jinqing Extract

[0050] Extractant: ethyl acetate, before using ethyl acetate, add water to water saturation.

[0051] Use 5-15 times the amount of ethyl acetate to extract the extract, the flow rate is 40-60L / h, and the extraction temperature is 25°C.

[0052] The temperature change curve during the extraction process of Jinqing extract is as follows: figure 2 shown.

[0053] The traditional operation method in the prior art and the control method of the present invention are used to extract the golden green extract respectively, the extract is collected, and the extract is concentrated by a scraper to obtain a dry extract. Repeat the test 10 times to compare the stability of the two control methods, and the results are shown in Table 1.

[0054] The stability contrast of table 1 traditional operation method and control method of the present invention

[0055]

[0056] It can be seen from the above table that the relative standard deviation of the weight of ...

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Abstract

The invention provides a method and device of a serinus mozambicus mozambicus extract extraction technology. The method and device can achieve continuous and stable extraction of a serinus mozambicus mozambicus extract. The control method of the serinus mozambicus mozambicus extract extraction technology comprises the following steps of 1, extracting agent preparation control, wherein water saturation ethyl acetate is prepared inside a preparation tank to be adopted as an extracting agent; 2, extraction tower constant volume control, wherein a weighing sensor is arranged inside an extract storage tank, the total weight of the extract is worked out, and the extract is uniformly distributed into extraction columns of the extraction tower through a weight reduction method; 3, extraction control, wherein the extracting agent in the step 1 is added into the extraction tower, and when the addition amount of water saturation ethyl acetate added into the extraction tower reaches the total volume of the extraction tower, the extraction process is ended; 4, extracting agent temperature control, wherein the real-time temperature of the extracting agent inside the extraction tower is detected, and when the real-time temperature of the extracting agent inside the extraction tower is lower than a set value, the temperature of the extracting agent inside the preparation tank is regulated; 5, extraction tower liquid level control, wherein when the liquid level reaches the high level, an alarm is given or extraction is stopped.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine pharmacy, in particular to a method and device for controlling the extraction process of Jinqing extract. Background technique [0002] Reduning Injection is a new drug independently developed by Jiangsu Kangyuan Pharmaceutical Co., Ltd. It is a compound injection of traditional Chinese medicine, which is mainly extracted and refined from three traditional Chinese medicines of honeysuckle, gardenia and Qinghao. The liquid produced by extracting honeysuckle and Artemisia annua with a certain solvent at a certain temperature is called Jinqing extract. The extraction process of Jinqing extract is an important link in the production process of Reduning Injection, which has great influence on the safety and effectiveness of the final product. Performance, stability, etc. play a vital role. Extraction is the process of dissolving active ingredients from the extract with a certain solvent. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D11/02A61K36/355A61K36/282
CPCA61K36/282A61K36/355B01D11/02B01D11/0207B01D11/0284B01D11/0288A61K2300/00
Inventor 萧伟刘雪松陈勇李页瑞凌娅王振中范庆龙包乐伟戚怀志陈永杰
Owner JIANGSU KANION PHARMA CO LTD
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