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Application of Clostridium butyricum in preparation of preparations for preventing or treating depression

A technology of Clostridium butyricum and depression, applied in the direction of bacteria, medical preparations containing active ingredients, nervous system diseases, etc.

Inactive Publication Date: 2017-02-22
QINGDAO EASTSEA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor found through research that Clostridium butyricum can effectively prevent or treat depression, is safe and has no toxic side effects, and the effect is better than that of Bifidobacterium, and there is no relevant research report, so we apply for this invention patent

Method used

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  • Application of Clostridium butyricum in preparation of preparations for preventing or treating depression

Examples

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preparation Embodiment 1

[0032] Preparation Example 1 The preparation of Clostridium butyricum powder

[0033] 1 Preparation of bacterial powder and identification of strains

[0034] Take a human feces sample, then put the sample in a sterilized anaerobic bottle, blow in nitrogen gas and mix well at the same time, quickly take 2 grams of sample from it and add it to 18 mL of sterilized diluent, blow in nitrogen gas and mix well at the same time, In the bacteria operating table, carry out 10 -1 、10 -2 、10 -3 、10-4 , 10 -5 , 10 - 6 , 10 -7 Gradient dilution, take 10 -5 , 10 -6 , 10 -7 Three dilution gradients were spread on the solid medium for the selective single colony isolation of Clostridium butyricum, placed in an anaerobic tank, cultured at 37°C for 48 hours, and selected single colonies with good growth were inoculated in the liquid amplification In the culture medium, place it in an anaerobic tank, and anaerobically expand and cultivate at 37° C. for 48 hours. After centrifuging (12...

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Abstract

The invention discloses application of Clostridium butyricum in the preparation of preparations for preventing or treating depression, and particularly relates to the application of the Clostridium butyricum in depression preventing or treating and depressive symptom relieving.

Description

technical field [0001] The invention relates to the application of Clostridium butyricum in the preparation of preparations for preventing or treating depression, in particular to using Clostridium butyricum to prevent or treat depression and reduce symptoms of depression. Background technique [0002] The pathogenesis of depression is complex, the clinical syndromes are diverse, and the course of the disease is long and easy to relapse. Depression occurs in people from all countries, social classes and cultural environments around the world. With the development of society and the increase of stressors, the incidence rate is also increasing year by year. The World Health Organization (WHO) predicts that by 2020, depression will become the most serious disease burden in developing countries, and major depression will become the second leading cause of death and disability by then. [0003] Moderate to severe depression is mostly caused by huge life and work pressure, and s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/741A61K35/745A61P25/00C12N1/20
Inventor 崔云龙赵婀姿李洪福
Owner QINGDAO EASTSEA PHARMA
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