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Device and formulation for topical treatment of pain affecting the vulvar area of the female human genital organ

A technology for genital, topical treatment, applied in the field of pain devices, able to solve problems such as no advice

Inactive Publication Date: 2017-02-22
GRUNENTHAL GMBH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

None of these devices are suggested to treat pain in the vulvar area of ​​the female body

Method used

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  • Device and formulation for topical treatment of pain affecting the vulvar area of the female human genital organ
  • Device and formulation for topical treatment of pain affecting the vulvar area of the female human genital organ
  • Device and formulation for topical treatment of pain affecting the vulvar area of the female human genital organ

Examples

Experimental program
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Effect test

example 1

[0089] a) A 28-year-old Caucasian female has presented with an 18-month history of vulvar pain. She described a generalized sharp stabbing pain localized to her labia and vestibule and usually triggered by touching, contact with tight clothing, and intercourse. She also complained of hypersensitive sensations to touch in the vestibule. On average, she rated her overall vulvar pain at 6-7 on a pain scale of 0-10, where 10 corresponds to the worst pain imaginable and 0 corresponds to no pain.

[0090] Obstetrical medical evaluation and imaging studies (including MRI of the pelvis) fail to detect any specific etiology such as infection, skin inflammation, and pelvic lesion structures. She was diagnosed with vulvodynia. Multiple treatment attempts (including: 1) oral medications such as tricyclic antidepressants, gabapentin, pregabalin, duloxetine; 2) various OTC creams; 3) pudendal nerve blocks) can lead to intolerable side effects and / or no significant beneficial effects.

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Abstract

The present invention relates to a device for the topical treatment of pain affecting the vulvar area of the female human genital organ, a formulation for use in the device according to the invention, and a kit comprising the device according to the present intention. Additionally, the present invention relates to a method of topical treatment of pain affecting the vulvar area of the female human genital organ, said method using the device according to the present invention. The device is a layered article shaped to be placed in use inside a female undergarment and at least partially in skin contact with the female vulvar area and comprises a topical formulation.

Description

technical field [0001] The present invention relates to a device for the local treatment of pain affecting the vulvar area of ​​the female genital organs, formulations for use in the device according to the invention and a kit comprising the device according to the invention. In addition, the invention relates to a method for the local treatment of pain affecting the vulvar area of ​​the female genital organs, said method using a device according to the invention. Background technique [0002] Vulvodynia is a chronic pain syndrome affecting the vulvar area of ​​the female genital organs. Vulvodynia primarily occurs without an identifiable cause or visible pathology. The condition can range from mild to severe and can manifest in specific areas of the vulva or in its entirety, although a higher prevalence has been reported in the vestibular region of the vulva, termed vulvar vestibulitis syndrome (VVS ). Although there is no known cure for vulvodynia, typical treatment is ...

Claims

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Application Information

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IPC IPC(8): A61L15/44A61K45/00A61K31/167A61P29/00
CPCA61K9/0014A61K9/0034A61K31/167A61K45/00A61L15/44A61L2300/204A61L2300/432A61L2300/102A61P15/00A61P23/02A61P29/00A61P43/00A61M31/00A61M2210/14
Inventor A.迪米诺M.帕帕加洛M.理查德森F.格斯泰默E.G.克格拉斯J.德尔夫加乌A.肖尔茨J.范尼尔
Owner GRUNENTHAL GMBH
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