A preparation method of flavored Xiaochaihu granule and application of flavored Xiaochaihu granule

A technology of Xiao Chai Hu granules and Chai Hu, which is applied to medical preparations containing active ingredients, pharmaceutical formulations, plant/algae/fungus/moss ingredients, etc., can solve the problems of low active ingredients and purity, insufficient application, etc. Conducive to human body absorption, improving effect, improving the effect of active ingredients and purity

Active Publication Date: 2020-01-14
东莞市中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, Bupleurum traditional Chinese medicine is not only considered to have low active ingredients and low purity, but also is not widely used in spleen and stomach medicines. Therefore, it is necessary to carry out more in-depth research and improvement on the preparation of Bupleurum medicine to improve the efficacy of Bupleurum medicine. Active ingredients and their application in spleen and stomach medicine

Method used

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  • A preparation method of flavored Xiaochaihu granule and application of flavored Xiaochaihu granule
  • A preparation method of flavored Xiaochaihu granule and application of flavored Xiaochaihu granule
  • A preparation method of flavored Xiaochaihu granule and application of flavored Xiaochaihu granule

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Embodiment 1

[0047] A kind of preparation method of flavored Xiaobupleurum granules in the present embodiment, comprises the following steps:

[0048] Step 1, Extraction of Bupleurum volatile oil

[0049] (1) Distillation equipment is installed: connect the flask, condenser, and oil-water separator successively from left to right, and the flask is placed in a heating device;

[0050] (2) Distilling Bupleurum volatile oil: put Bupleurum in a flask, add water, the weight ratio of Bupleurum to water is 1:6, then add extractant to the oil-water separator, the volume ratio of volatile oil to extractant 1:0.1, then start the heating device to heat the flask, and extract the bupleurum volatile oil through the azeotropic-distillation coupling process, wherein the extractant is liquid paraffin;

[0051] (3) The first extraction of Bupleurum volatile oil: add ethanol to the oil-water separator, the volume ratio of the mixture of volatile oil and extractant to ethanol is 1:0.5, then extract and cent...

Embodiment 2

[0067] A kind of preparation method of flavored Xiaobupleurum granules in the present embodiment, comprises the following steps:

[0068] Step 1, Extraction of Bupleurum volatile oil

[0069] (1) Distillation equipment is installed: connect the flask, condenser, and oil-water separator successively from left to right, and the flask is placed in a heating device;

[0070] (2) Distilling Bupleurum volatile oil: put Bupleurum in a flask, add water, the weight ratio of Bupleurum to water is 1:9, then add extractant to the oil-water separator, the volume ratio of volatile oil to extractant 1:2, then start the heating device to heat the flask, and extract the bupleurum volatile oil through the azeotropic-distillation coupling process, wherein the extractant is vaseline;

[0071] (3) The first extraction of Bupleurum volatile oil: add ethanol to the oil-water separator, the volume ratio of the mixture of volatile oil and extractant to ethanol is 1:3, then extract and centrifuge, rem...

Embodiment 3

[0086] A kind of preparation method of flavored Xiaobupleurum granules in the present embodiment, comprises the following steps:

[0087] Step 1, Extraction of Bupleurum volatile oil

[0088] (1) Distillation equipment is installed: connect the flask, condenser, and oil-water separator successively from left to right, and the flask is placed in a heating device;

[0089] (2) Distilling Bupleurum volatile oil: put Bupleurum in a flask, add water, the weight ratio of Bupleurum to water is 1:7, then add extractant to the oil-water separator, the volume ratio of volatile oil to extractant 1:1.5, then start the heating device to heat the flask, and extract the bupleurum volatile oil through the azeotropic-distillation coupling process, wherein the extractant is lanolin;

[0090] (3) The first extraction of Bupleurum volatile oil: Add ethanol to the oil-water separator, the volume ratio of the mixture of volatile oil and extractant to ethanol is 1:2, then extract and centrifuge, re...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, and in particular relates to modified common goldenrop granules as well as a preparation method and applications of the modified common goldenrop granules. The modified common goldenrop granules are prepared from the following components in percentage by weight: 2%-10% of bupleurum chinense volatile oil, 20%-70% of modified common goldenrop granule extract powder, and 20%-70% of dextrin. The modified common goldenrop granules have the advantages that the carrying is convenient, the content of active ingredients is high, and the absorption is convenient. The preparation method of the modified common goldenrop granules comprises the following steps: 1, extracting the bupleurum chinense volatile oil, 2, preparing a clathrate compound; 3, preparing the modified common goldenrop granule extract powder, and 4, carrying out pelleting. With the adoption of the preparation method, the medicinal ingredients of common goldenrop can be well purified, and meanwhile, the prepared granules are convenient to carry; the modified common goldenrop granules can be used for preparing the medicines for treating peptic ulcer and chronic gastritis complications, and thus the application range of the common goldenrop granules in the medicines for treating spleen and stomach diseases is expanded.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a preparation method of flavored Xiao Bupleuri granules and an application of the flavored Xiao Bupleuri granules. Background technique [0002] Xiao Chaihu Decoction comes from "Treatise on Febrile Diseases", the original text "Treat fever five or six days, stroke, alternating cold and heat, fullness of chest and flank pain, hehe does not want to eat, upset and vomiting, or chest upset but not vomiting, or thirsty, or abdominal pain, or For those who suffer from abdominal pain, palpitations, dysuria, lack of thirst, mild fever, or cough, Xiao Chaihu Decoction is the main remedy." Composed of ginger, jujube and other medicines, it is suitable for Shaoyang syndrome, alternating cold and heat, bitter fullness in the chest and flanks, silent reluctance to eat, upset and vomiting, bitter mouth, dry throat, dizziness, stringy pulse, jaundice and Shaoyang syndrome...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16
CPCA61K9/1652A61K9/1682A61K36/076A61K36/233A61K36/284A61K36/344A61K36/484A61K36/539A61K36/718A61K36/725A61K36/8888A61K36/9068A61K2236/331A61K2236/35A61K2236/39A61K2300/00
Inventor 周爱军刘焱文
Owner 东莞市中医院
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