Photothermal waveguide-based microfluidic chip and its microfluidic method

Abstract

The invention discloses a micro-fluidic chip based on a photothermal waveguide and a micro-fluidic method of the micro-fluidic chip. The chip comprises the photothermal waveguide, a microflow chamber, an optical signal input port, a microflow pump and microfluid, wherein the photothermal waveguide is formed by assembling a photothermal conversion material with a micro-nano waveguide, the photothermal waveguide is submerged at the bottom of the microflow chamber, and an optical signal sent by a light source is transmitted on the photothermal waveguide; and the microflow pump is connected with the microflow chamber by virtue of a pipeline. The photothermal waveguide generates heat under the excitation of the optical signal, then generates a temperature gradient in the whole microfluid, and inductively generates buoyancy convection taking vertical type vortex flow as a characteristic and thermo-capillary convection taking horizontal type vortex flow as a characteristic. By virtue of the microflow pump, the thickness of a fluid layer can be changed so as to control a flow mode of the microfluid. By virtue of the power of the optical signal, the heat of the photothermal waveguide can be changed so as to control the flow intensity of the microfluid. The method disclosed by the invention is quick and convenient, is low in cost, is efficient, and can generate multiple forms of vortex flows.

Description

technical field [0001] The invention belongs to the field of optofluidic technology, and in particular relates to a microfluidic chip based on a photothermal waveguide and a microfluidic method thereof. Background technique [0002] In the microfluidic chip, the generation and control of microfluidic flow is one of the basic operations to realize the sample preparation, reaction, separation, detection and other modules of the biochemical analysis process. Early microfluidic flow technologies were mainly realized through micropump valve devices and complex fluid channels. In the middle and late 21st century, with the development of devices towards integration and miniaturization, the vigorous development of microfluidic chip technology and the organic combination of optical technology, the two complement each other, created the birth of a new technology field, that is, optically controlled microfluidic technology . The method of using photothermal materials to convert light...

AI Technical Summary

Problems solved by technology

In view of the limitations of the current traditional laser beam, the current light-controlled microfluidic technology has several major deficiencies: 1. The excitation equipment is complex and the loss is large

Starting from the light source, the laser needs to go through a complex optical path and then interact with the material. Optical components will scatter and absorb part of the energy, resulting in waste

2. The form of fluid flow generated by the direct laser excitation method is single, and generally only stimulates the vertical flow of the fluid, which ultimately causes the function of the light-controlled microflow technology to be limited to fluid heat transfer and mass transfer.

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