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Smilax bockii warb pills and preparation process thereof

A technology of King Kong rattan pills and King Kong rattan, which is applied in the field of medicine, can solve the problems of affecting drug efficacy and slow disintegration speed of King Kong rattan preparations, and achieve the effects of fast dissolution speed, good therapeutic effect and fast disintegration speed

Active Publication Date: 2017-06-06
怀化正好制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The object of the present invention is to provide a kind of Jingangteng pill and its preparation process, to solve the technical problem in the prior art that the drug effect is affected by the slow disintegration speed of Jingangteng preparation

Method used

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  • Smilax bockii warb pills and preparation process thereof
  • Smilax bockii warb pills and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A kind of Jingang rattan pill, comprising the following components in mass percentage:

[0029] King Kong vine extract 50%, disintegrant 12.5%, dextrin 30%, polypropylene resin ethanol solution 2.5%, magnesium stearate 5%.

[0030] The disintegrant is a mixture of calcium oxide and carboxymethyl chitosan, and its preparation method is: mix carboxymethyl chitosan and ethanol at a mass ratio of 1:0.7, stir until it is wet, and mix calcium oxide Mix with the above-mentioned wet mixture, make the wet mixture adhere to the surface of calcium oxide, and finally dry it to volatilize ethanol to obtain a disintegrating agent; wherein the mass ratio of calcium oxide to carboxymethyl chitosan is 1 :1.

[0031] A kind of preparation technology of Jingang rattan pill, comprises the following steps:

[0032] (1) Extraction of King Kongteng extract: first with King Kongteng and the mass concentration of 55% ethanol aqueous solution mixed in a mass ratio of 1:15, then crushed and bea...

Embodiment 2

[0036] A kind of Jingang rattan pill, comprising the following components in mass percentage:

[0037] King Kong vine extract 45%, disintegrant 10%, pregelatinized starch 15%, microcrystalline cellulose 20%, polyvinylpyrrolidone ethanol solution 0.1%, talcum powder 9.9%.

[0038] The disintegrant is a mixture of calcium oxide and carboxymethyl chitosan, and its preparation method is: mix carboxymethyl chitosan and ethanol at a mass ratio of 1:0.4, stir until it is wet, and mix calcium oxide Mix with the above-mentioned wet mixture, make the wet mixture adhere to the surface of calcium oxide, and finally dry and volatilize the ethanol to obtain a disintegrating agent; wherein the mass ratio of calcium oxide to carboxymethyl chitosan is 0.5 :1.

[0039] A kind of preparation technology of Jingang rattan pill, comprises the following steps:

[0040] (1) Extraction of King Kongteng extract: first mix King Kongteng with 50% ethanol aqueous solution at a mass ratio of 1:10, then g...

Embodiment 3

[0044] A kind of Jingang rattan pill, comprising the following components in mass percentage:

[0045] King Kong vine extract 55%, disintegrant 15%, lactose 15%, ethanol solution 5%, micronized silica gel 10%.

[0046] The disintegrant is a mixture of calcium oxide and carboxymethyl chitosan, and its preparation method is: mix carboxymethyl chitosan and ethanol at a mass ratio of 1:1.0, stir until it is wet, and mix calcium oxide Mix with the above-mentioned wet mixture, make the wet mixture adhere to the surface of calcium oxide, and finally dry it to volatilize ethanol to obtain a disintegrating agent; wherein the mass ratio of calcium oxide to carboxymethyl chitosan is 1.5 :1.

[0047] A kind of preparation technology of Jingang rattan pill, comprises the following steps:

[0048] (1) Extraction of King Kongteng extract: first with King Kongteng and the mass concentration of 60% ethanol aqueous solution mixed in a mass ratio of 1:20, then minced and beating to obtain King...

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Abstract

The invention provides smilax bockii warb pills and a preparation process thereof, and relates to the technical field of medicines. The smilax bockii warb pills are prepared from the following components in percentage by mass: 45 to 55 percent of a smilax bockii warb extract, 10 to 15 percent of a disintegrating agent, 20 to 40 percent of a filler, 0.1 to 5 percent of an adhesive, and 0 to 10 percent of a lubricating agent, wherein the disintegrating agent is a mixture of calcium oxide and water-soluble chitosan. The preparation method of the smilax bockii warb pills comprises the following steps: mixing the water-soluble chitosan with the ethyl alcohol according to the mass ratio of 1:(0.4 to 1.0), stirring the mixture till the mixture is in a wet state, mixing calcium oxide with the wet mixture to enable the wet mixture to be adhered to the surface of the calcium oxide, and finally carrying out drying to volatilize the ethyl alcohol, thus obtaining the disintegrating agent, wherein the mass ratio of the calcium oxide to the water-soluble chitosan is (0.5 to 1.5):1. The smilax bockii warb pills disclosed by the invention are high in effective component content, high in disintegrating speed, high in effective component dissolving speed and good in treating effect.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular, to a kind of Jingangteng Pill and its preparation process. Background technique [0002] Gynecological inflammatory diseases are common and frequently-occurring diseases of women. There are many symptoms, mainly including pelvic inflammatory disease, vaginitis, cervicitis, adnexitis, uterine fibroids, leukorrhea and so on. At present, the treatment of gynecological inflammatory diseases mainly includes internal treatment and external treatment. According to the incomplete statistics of the World Health Organization, the incidence of various gynecological diseases in women is above 65%. my country's relevant data survey shows that the incidence of gynecological diseases in women of childbearing age is above 70%. Globally, gynecological medications form an important part of pharmacology. In particular, the advent of new drugs and the adjustment of product structure have driven the...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61K9/20A61K47/36A61K47/02A61P15/00A61P15/02A61P15/08A61P35/00
CPCA61K9/2009A61K9/2054A61K36/896A61K36/90A61K2236/333A61K2236/39A61K2236/51A61K2236/53
Inventor 颜家伟颜坚生张光贤郑丹邓忠宋思才
Owner 怀化正好制药有限公司
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