A chain of degradable radioactive particles with shape memory function

Abstract

The invention relates to a radioactive brachytherapy device, in particular to a degradable radioactive particle chain with shape memory function. The degradable radioactive particle chain includes at least one radioactive particle and a wrapping layer; the radioactive particle is a radioactive source, and at least part of it is wrapped by the wrapping layer; the wrapping layer material includes polycaprolactone PCL. The particle chain made of PCL as the main molding material has a shape memory function, which makes the implantation of the particle chain easy, and at the same time can maintain a certain supporting force for the lumen and glands, ensuring that the particle chain does not affect the tube after the implantation operation. The normal physiological functions of the cavity and glands; at the same time, PCL has the advantages of biodegradability and low melting point.

Description

technical field

[0001] The invention relates to a radioactive brachytherapy device, in particular to a degradable radioactive particle chain with shape memory function. Background technique

[0002] Malignant tumors have always been a major disease that threatens human health, and interstitial brachytherapy of tumors using radioactive particles is a new technology developed in recent decades. Radioactive particles are a small radioactive source. The radioactive isotope is packed in a titanium tube, and the two ends are welded by laser or electron beam technology to form a sealed source. The size is generally 0.8mm in outer diameter and 4.5mm in length. Nuclides commonly used in radioactive particles are 192 Ir, 198 Au, 169 Y, 131 Cs, 103 Pd and 125 I etc., especially 103 Pd and 125 I. Brachytherapy implants radioactive particles directly into the lesion, and continuously irradiates at close range, destroying the DNA double bond of the tumor cell nucleus, killing or ...

Images