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Yugui children anti-diarrheal gel paste and preparation method thereof

A gel cream, children's technology, applied in the field of medicine, can solve the problems of poor stability, unfavorable absorption, inconvenient use, etc., and achieve the effect of good stability, convenient treatment, and convenient use

Inactive Publication Date: 2017-06-30
张剑锋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Based on this, in view of the above problems, the present invention provides a Yugui Xiaoer antidiarrheal gel paste and its preparation method. This application avoids the disadvantages of poor stability of traditional medicines, inconvenient use and disadvantages for human body absorption, and adopts the form of gel paste. It has strong moisture retention, aging resistance, can be repeatedly peeled off, and the administration can be stopped at any time. It is safe to use, less irritating, less allergic, accurate in dose, and fixed in area.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A yugui infant antidiarrheal gel paste, which is composed of the following raw materials in parts by weight: 15 parts of evodia rutaecarpa; 8 parts of cinnamon; 6 parts of atractylodes rhizome; 3 parts of coptis; 4 parts of clove; share.

[0031] A preparation method of Yugui children's antidiarrheal gel cream, comprising the following steps:

[0032] S1, using 70% concentration of ethanol to reflux to extract evodiamine and evodiamine in Evodia rutaecarpa, and to extract alkaloids in Coptidis Rhizoma by using the ethanol reflux method;

[0033] S2, extracting the volatile oil in cloves, cinnamon and woody respectively; extracting gallic acid in Galla, and making a thick paste;

[0034] S3, mixing the substances extracted in step S1 and step S2 into a medicinal solution;

[0035] S4. Add sodium polyacrylate, gelatin, sodium carboxymethylcellulose, and polyvinylpyrrolidone into the beaker, add quantitative water and glycerin, and stir evenly;

[0036] S5. Add aluminum...

Embodiment 2

[0038] A yugui infant antidiarrheal gel paste, which is composed of the following raw materials in parts by weight: 10 parts of evodia rutaecarpa; 6 parts of cinnamon; 8 parts of atractylodes rhizome; 3.5 parts of coptis; 5 parts of clove; share.

[0039] A preparation method of Yugui children's antidiarrheal gel cream, comprising the following steps:

[0040] S1, using 70% concentration of ethanol to reflux to extract evodiamine and evodiamine in Evodia rutaecarpa, and to extract alkaloids in Coptidis Rhizoma by using the ethanol reflux method;

[0041] S2, extracting the volatile oil in cloves, cinnamon and woody respectively; extracting gallic acid in Galla, and making a thick paste;

[0042] S3, mixing the substances extracted in step S1 and step S2 into a medicinal solution;

[0043] S4. Add sodium polyacrylate, gelatin, sodium carboxymethylcellulose, and polyvinylpyrrolidone into the beaker, add quantitative water and glycerin, and stir evenly;

[0044] S5. Add alumin...

Embodiment 3

[0046] A yugui infant antidiarrheal gel paste, which is composed of the following raw materials in parts by weight: 8 parts of evodia rutaecarpa; 4 parts of cinnamon; 6 parts of atractylodes rhizome; 3 parts of coptis; 4 parts of clove; share.

[0047] A preparation method of Yugui children's antidiarrheal gel cream, comprising the following steps:

[0048] S1, using 70% concentration of ethanol to reflux to extract evodiamine and evodiamine in Evodia rutaecarpa, and to extract alkaloids in Coptidis Rhizoma by using the ethanol reflux method;

[0049] S2, extracting the volatile oil in cloves, cinnamon and woody respectively; extracting gallic acid in Galla, and making a thick paste;

[0050] S3, mixing the substances extracted in step S1 and step S2 into a medicinal liquid;

[0051] S4. Add sodium polyacrylate, gelatin, sodium carboxymethylcellulose, and polyvinylpyrrolidone into the beaker, add quantitative water and glycerin, and stir evenly;

[0052] S5. Add aluminum tr...

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PUM

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Abstract

The invention discloses Yugui children anti-diarrheal gel paste. The paste is prepared from 8-15 parts of fructus evodiae, 4-8 parts of cinnamomum cassia, 6-8 parts of rhizoma atractylodis, 3-4 parts of rhizoma coptidis, 4-6 parts of flos caryophylli, 4-6 parts of radix aucklandiae, 6-8 parts of galla chinensis and 30-45 parts of excipients. The preparation method comprises steps as follows: alkaloid is extracted from fructus evodiae and rhizoma coptidis with an ethanol reflux method; volatile oil in flos caryophylli, cinnamomum cassia and radix aucklandiae are extracted; gallic acid in galla chinensis is extracted and made into thick paste; sodium polyacrylate, gelatin, sodium carboxymethylcellulose and polyvinylpyrrolidone are added to a beaker, water, glycerol, aluminum trichloride, citric acid, aerosil, a liquid medicine and the volatile oil are added sequentially, the mixture is stirred uniformly and applied to a backlining material, and emplastrum is prepared. The defects that traditional medicines are poor in stability, inconvenient to use and difficult to absorb are avoided; with the adoption of the gel paste form, the gel paste can be repeatedly peeled off and attached, medication can be stopped at any time, and the gel paste is safe and has little irritation and low probability of causing allergies.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a Yugui children's antidiarrheal gel ointment and a preparation method thereof. Background technique [0002] The original formula of Yugui Xiaoer Zhixie Gel Ointment has definite clinical curative effect, but it is inconvenient to use. In order to meet the requirements of modern mass production and ensure clinical efficacy. After the medicine of the application is extracted, it absorbs quickly, and the product is small in size, strong in stability and convenient to use. [0003] Patent application number: 200810157397.X discloses a traditional Chinese medicine composition for the treatment of infantile diarrhea. Pulsatilla 10-15, Clove 10-15, Atractylodes 15-20, Cinnamon 10-15, Evodia 10-15, White Pepper 15-20, Codonopsis 10-15, Angelica 15-20, Atractylodes 10-15, Woody 15- 20, Divine Comedy 15-20. [0004] Although the above-mentioned patent application contains raw materi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/754A61K9/70A61P1/12A61K35/64
CPCA61K47/42A61K9/7023A61K35/63A61K36/284A61K36/285A61K36/54A61K36/61A61K36/718A61K36/754A61K2236/51A61K2236/39A61K2236/333A61K2236/331A61K2300/00
Inventor 张剑锋
Owner 张剑锋
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