A kind of pharmaceutical composition with hypolipidemic function and preparation method of capsule preparation thereof

A technology for reducing blood lipids and compositions, which is applied in the field of preparation of pharmaceutical compositions and capsule preparations, can solve the problems of expensive side effects and other problems, and achieve the effects of ensuring food safety, high bioavailability, and simple preparation process

Active Publication Date: 2020-12-08
HENAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the use of lipid-lowering drugs, such as statins, is currently the most common and widely used method for the treatment of hyperlipidemia, but due to its high price and side effects of these drugs, people began to study and develop more effective and Safer alternative products for lowering blood lipids

Method used

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  • A kind of pharmaceutical composition with hypolipidemic function and preparation method of capsule preparation thereof
  • A kind of pharmaceutical composition with hypolipidemic function and preparation method of capsule preparation thereof
  • A kind of pharmaceutical composition with hypolipidemic function and preparation method of capsule preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] A pharmaceutical composition with the function of lowering blood fat, which is composed of the following raw materials in weight ratio: 640 parts of eucommia seed oil, 690 parts of linseed oil, 450 parts of red yeast rice powder, 60 parts of eucommia male pollen, 20 parts of vitamin E, beeswax 20 servings.

[0043] The preparation method of the above-mentioned pharmaceutical composition with hypolipidemic function comprises the following steps:

[0044] (1) Weigh each raw material by weight; Wherein, eucommia seed oil is obtained through the following steps: eucommia ulmoides seed is screened, impurity-removed, pulverized to 55 mesh, sieved and loaded into subcritical extractor, and butane is used as Extraction solvent, the mass ratio of solid to liquid is 1:3.5, the extraction temperature is 35°C, the extraction time is 40 minutes, the extraction pressure is 0.4MPa, and the number of extractions is 5 times to obtain Eucommia ulmoides seed oil;

[0045] (2) Heat eucomm...

Embodiment 2

[0049] A pharmaceutical composition with the function of lowering blood fat, which is composed of the following raw materials in weight ratio: 890 parts of eucommia seed oil, 450 parts of linseed oil, 690 parts of red yeast rice powder, 20 parts of eucommia male pollen, 1 part of vitamin E, beeswax 60 servings.

[0050] The preparation method of the above-mentioned pharmaceutical composition with hypolipidemic function comprises the following steps:

[0051] (1) Weigh each raw material by weight; Wherein, eucommia seed oil is obtained through the following steps: eucommia ulmoides seed is screened, impurity-removed, pulverized to 65 mesh, sieved and loaded into a subcritical extractor, and butane is used as Extraction solvent, the mass ratio of solid to liquid is 1:4.5, the extraction temperature is 45°C, the extraction time is 50 minutes, the extraction pressure is 0.6MPa, and the extraction times are 3 times to obtain Eucommia ulmoides seed oil;

[0052] (2) Heat eucommia s...

Embodiment 3

[0056] A pharmaceutical composition with the function of lowering blood fat, which is composed of the following raw materials in weight ratio: 700 parts of eucommia seed oil, 620 parts of linseed oil, 520 parts of red yeast rice powder, 50 parts of eucommia male pollen, 15 parts of vitamin E, beeswax 30 servings.

[0057] The preparation method of the above-mentioned pharmaceutical composition with hypolipidemic function comprises the following steps:

[0058] (1) Each raw material is weighed by parts by weight; wherein, the eucommia seed oil is obtained through the following steps: eucommia ulmoides seeds are screened, impurity removed, crushed to 60 mesh, sieved and loaded into a subcritical extractor, and butane is used as Extraction solvent, the mass ratio of solid to liquid is 1:4, the extraction temperature is 40°C, the extraction time is 45 minutes, the extraction pressure is 0.5MPa, and the number of extractions is 4 times to obtain Eucommia ulmoides seed oil;

[0059...

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Abstract

The invention discloses a pharmaceutical composition with the function of lowering blood fat, which is composed of the following raw materials in weight ratio: 640-890 parts of eucommia seed oil, 450-690 parts of linseed oil, 20-60 parts of eucommia male pollen, vitamin E 1-20 parts, 20-60 parts of beeswax, 450-690 parts of main ingredient powder, the main ingredient powder is one of red yeast rice powder, natto powder and stinky soybean powder; the capsule preparation of the pharmaceutical composition is also disclosed method of preparation. All the components of the present invention are pure natural medicines or components extracted from natural medicines, with stable properties, high bioavailability, and mutual synergy of multiple active ingredients, which overcomes the need for combined medication, high drug prices, and large side effects of existing medicines. The disadvantage is that the preparation process is simple, and it is suitable for large-scale industrial production.

Description

technical field [0001] The invention belongs to the technical field of health care products, and in particular relates to a pharmaceutical composition with blood lipid-lowering function and a preparation method of capsule preparation thereof. Background technique [0002] With age, changes in eating habits, air pollution and other reasons, people's bodies have also been polluted to varying degrees. The blood is also inevitably polluted, resulting in darker blood color, thicker blood quality, slower blood circulation, excessive accumulation of garbage impurities such as cholesterol, fat, triglycerides in the blood, resulting in hardening of the blood vessel wall and vascular channels. Become narrower, thereby causing hypertension, hyperlipidemia, coronary arteriosclerosis, cardiovascular and cerebrovascular diseases, which seriously threaten human health. [0003] Due to abnormal fat metabolism or operation, one or more lipids in plasma are higher than normal, which is calle...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L33/12A23L33/105A23L21/20A23L33/15A23L33/10A23L7/104A23L11/00A23P10/30A61K36/899A61K36/55A61P3/06A23L11/50
CPCA61K36/899A61K36/062A61K36/46A61K36/48A61K36/55A23V2002/00A61K2236/19A23V2200/30A23V2200/326A23V2250/21A61K2300/00
Inventor 李钦梁晓炜李培杉丁艳霞张峰
Owner HENAN UNIVERSITY
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