A method for preparing microcrystalline cellulose from traditional Chinese medicine dregs

A technology for microcrystalline cellulose and traditional Chinese medicine residues, which is applied in the field of preparing microcrystalline cellulose, can solve the problem of not seeing microcrystalline cellulose, etc., and achieve the effects of improving purity and whiteness, simple preparation method and easy operation.

Active Publication Date: 2019-07-16
兰州名德药业有限公司
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, some people use soybean hulls, peanut shells, reeds, wheat straw, corn stalks, etc. to prepare microcrystalline cellulose, but there is no report on the preparation of microcrystalline cellulose using traditional Chinese medicine dregs. The successful development of the preparation of microcrystalline cellulose will open up a new way for the in-depth development and utilization of traditional Chinese medicine dregs resources

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A method for preparing microcrystalline cellulose from traditional Chinese medicine dregs
  • A method for preparing microcrystalline cellulose from traditional Chinese medicine dregs
  • A method for preparing microcrystalline cellulose from traditional Chinese medicine dregs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] a. Weigh 10g of Chinese medicine dregs in a digestion bottle, mix the Chinese medicine dregs with deionized water at a solid-to-liquid ratio of 1:20g / mL, that is, add 1g of Chinese herbal medicine dregs to 20ml of deionized water, boil for 120min, and centrifuge at 3500r / min for 10min , get filter residue;

[0030] b. Alkali treatment: add 0.04 g / ml sodium hydroxide solution to the filter residue obtained in step a at a solid-to-liquid ratio of 1:10 g / ml, treat in a water bath at 60° C. for 100 min, centrifuge to obtain the filter residue, wash and precipitate until neutral, and collect the filter residue;

[0031] c. Acid treatment: add distilled water to the filter residue obtained in step b at a solid-to-liquid ratio of 1:10 g / ml, adjust the pH value to 1.5 with hydrochloric acid with a mass concentration of 3%, and treat it at a constant temperature in a water bath at 80° C. for 60 minutes, centrifuge to obtain the filter residue, and wash to medium properties, dehy...

Embodiment 2

[0036] a. Weigh 10g of Chinese medicine dregs into a digestion bottle, mix the Chinese medicine dregs with deionized water at a solid-to-liquid ratio of 1:15g / mL, that is, add 15ml of deionized water to 1g of Chinese medicine dregs, boil for 120min, and centrifuge at 3500r / min for 5min , get filter residue;

[0037] b. Alkali treatment: add 0.08g / ml sodium hydroxide solution to the filter residue obtained in step a at a solid-to-liquid ratio of 1:15g / ml, treat in a water bath at 80°C for 60min, centrifuge to obtain the filter residue, wash and precipitate until neutral, and collect the filter residue;

[0038]c. Acid treatment: add distilled water to the filter residue obtained in step b at a solid-to-liquid ratio of 1:2g / ml, adjust the pH value to 1 with sulfuric acid with a mass concentration of 5%, and treat it at a constant temperature in a water bath at 60°C for 80 minutes, centrifuge to obtain the filter residue, and wash to medium properties, dehydration and drying;

...

Embodiment 3

[0043] a. Weigh 10g of Chinese medicine dregs in a digestion bottle, mix the Chinese medicine dregs with deionized water at a solid-to-liquid ratio of 1:30g / mL, that is, add 1g of Chinese herbal medicine dregs to 30ml of deionized water, boil for 100min, and centrifuge at 3000r / min for 20min , get filter residue;

[0044] b. Alkali treatment: add 0.02 g / ml sodium hydroxide solution to the filter residue obtained in step a at a solid-to-liquid ratio of 1:12 g / ml, treat in a water bath at 50° C. for 120 min, centrifuge to obtain the filter residue, wash and precipitate until neutral, and collect the filter residue;

[0045] c. Acid treatment: Add distilled water to the filter residue obtained in step b at a solid-to-liquid ratio of 1:5g / ml, adjust the pH value to 2 with phosphoric acid with a mass concentration of 5%, and treat it at a constant temperature in a water bath at 50°C for 90 minutes, centrifuge to obtain the filter residue, and wash to medium properties, dehydration ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
quality scoreaaaaaaaaaa
purityaaaaaaaaaa
degree of polymerizationaaaaaaaaaa
Login to view more

Abstract

The invention discloses a method for preparing microcrystalline cellulose from Chinese herb residue, comprising the following steps: a, mixing Chinese herb residue and distilled water, slightly boiling, and centrifuging to obtain filter residue; b, alkali treatment: adding the filter residue into a sodium hydroxide solution, carrying out water-bath treatment, centrifuging, washing precipitate to neutral level, and collecting filter residue; c, acid treatment: adding distilled water to the filter residue, adjusting pH to 1-2, carrying out water-bath treatment, centrifuging to obtain filter residue, washing to neutral level, and drying; d, extraction of Chinese herb residue crude cellulose: adding the filter residue into bleaching liquid, carrying out water-bath treatment, carrying out suction filtration, washing to neutral level, and drying to constant weight to prepare the microcrystalline cellulose. The preparation method of the invention is beneficial to raise utilization rate of waste Chinese herb residue resources and provides a safe, cheap and convenient raw material resource for the production of microcrystalline cellulose.

Description

technical field [0001] The invention relates to a method for preparing microcrystalline cellulose, in particular to a method for preparing medicinal auxiliary materials and food additive microcrystalline cellulose from residues of traditional Chinese medicine. Background technique [0002] Chinese herbal medicines are drugs used to prevent, diagnose, treat diseases or regulate human body functions under the guidance of TCM theories. Chinese herbal medicines are mostly herbal medicines, and some animal medicines, mineral medicines, and chemical and biological medicines. The rapid development of the traditional Chinese medicine industry has brought economic benefits to people, but the treatment and recycling of traditional Chinese medicine residues is a major problem. The annual output of traditional Chinese medicine dregs in our country is very large, up to several thousand tons. At present, people's treatment of traditional Chinese medicine residue is not very environmenta...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): C08B15/02
CPCC08B15/02
Inventor 任海伟王聪陈鑫张丙云李志忠王玉玮李志杰喇慧翔王永刚刘晓风张百刚
Owner 兰州名德药业有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap