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Antibacterial and anti-inflammatory drug and preparation method thereof

An antibacterial, anti-inflammatory, and pharmaceutical technology, which is applied in the direction of anti-inflammatory agents, local antibacterial agents, and pharmaceutical formulations, can solve problems such as dependence and drug resistance, and rapid healing of tissues that are not easily damaged, so as to avoid secondary infection damage and promote Effect of wound repair and healing, polarity enhancement

Active Publication Date: 2017-07-18
CHONGQING LIJIAN SCI & TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of antibiotic antibacterial agent is prone to dependence and drug resistance, and it is not easy to make wound tissue heal quickly

Method used

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  • Antibacterial and anti-inflammatory drug and preparation method thereof
  • Antibacterial and anti-inflammatory drug and preparation method thereof
  • Antibacterial and anti-inflammatory drug and preparation method thereof

Examples

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preparation example Construction

[0028] The present invention also provides a preparation method of the above-mentioned antibacterial and anti-inflammatory agent, which includes:

[0029] S1: After sodium tetraborate and propylene glycol are mixed evenly by weight parts, then mixed with pure water whose temperature is 80~100°C;

[0030] Mixing sodium tetraborate and propylene glycol first is conducive to the full dispersion of the two, and then mixing with pure water at a temperature of 80-100°C can effectively avoid emulsification.

[0031] In a preferred embodiment of the present invention, the step of mixing sodium tetraborate and propylene glycol includes: mixing sodium tetraborate with a skin penetration enhancer, stirring for 15-25 minutes, then mixing with propylene glycol, and continuing stirring for 15-25 minutes. The addition of a skin penetration enhancer makes the agent more permeable, can quickly penetrate into the deep tissue of the damaged wound, and interact with bacteria to interfere with the...

Embodiment 1

[0041] This embodiment provides an antibacterial and anti-inflammatory agent, and the raw materials of this antibacterial and anti-inflammatory agent include by weight parts:

[0042] 20 parts of ascorbic acid, 20 parts of sodium tetraborate, 10 parts of propylene glycol, 20 parts of glycerin, 1 part of phenoxyethanol, and 60 parts of pure water.

[0043] The preparation method of this medicament is:

[0044] Mix sodium tetraborate and propylene glycol evenly in parts by weight, and then mix with pure water at a temperature of 100°C; then slowly add glycerin and mix evenly, and then slowly add ascorbic acid when the temperature drops to 70°C, and then mix with phenoxyethanol After mixing evenly, an antibacterial solution is obtained, and filtered to obtain the antibacterial and antiphlogistic agent.

Embodiment 2

[0046] This embodiment provides an antibacterial and anti-inflammatory agent, and the raw materials of this antibacterial and anti-inflammatory agent include by weight parts:

[0047] 10 parts of ascorbic acid, 10 parts of sodium tetraborate, 20 parts of propylene glycol, 10 parts of glycerin, 2 parts of phenoxyethanol, and 50 parts of pure water.

[0048] The preparation method of this medicament is:

[0049] Mix sodium tetraborate and propylene glycol evenly in parts by weight, and then mix with pure water at a temperature of 80°C; then slowly add glycerin and mix evenly, and then slowly add ascorbic acid when the temperature drops to 60°C, and then mix with phenoxyethanol After mixing evenly, an antibacterial solution is obtained, and filtered to obtain the antibacterial and antiphlogistic agent.

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Abstract

The invention provides an antibacterial and anti-inflammatory drug and a preparation method thereof, and belongs to the field of wound repair preparations. The antibacterial and anti-inflammatory drug is prepared from the following raw materials: ascorbic acid, sodium tetraborate, propylene glycol, phenoxyethanol, glycerol and pure water. The preparation method comprises the steps of mixing the sodium tetraborate with the propylene glycol evenly and then mixing with the pure water of 80-100 DEG C; and slowly adding the glycerol for mixing evenly, lowering the temperature to 60-70 DEG C, slowly adding the ascorbic acid and then mixing with the phenoxyethanol evenly to obtain an antibacterial liquid and filtering. The method is mild in technological conditions and easy to implement; and the clear and transparent antibacterial and anti-inflammatory drug with good dispersity can be obtained through controlling the mixing order of the raw materials. The prepared antibacterial and anti-inflammatory drug has a broad-spectrum long-acting bactericidal function, and is capable of efficiently promoting wound repairing and healing, quickly healing a wound tissue and removing a scar.

Description

technical field [0001] The invention relates to the field of wound repair preparations, in particular to an antibacterial and anti-inflammatory agent and a preparation method thereof. Background technique [0002] Inflammation is a very common and very important pathological process in the human body. It mainly refers to the defensive response of living tissues with vascular system to damage factors composed of bacteria and viruses. Trauma infections on the body surface and most common and frequently-occurring diseases of major organs are inflammatory diseases. [0003] Vascular responses are central to the inflammatory process. Inflammation, which is usually referred to as "inflammation", is a defense response of the body to stimuli, manifested as redness, swelling, heat, pain and functional impairment. In the inflammatory process, on the one hand, damage factors directly or indirectly cause tissue and cell damage, and on the other hand, through inflammatory hyperemia and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/22A61K36/288A61K47/20A61K47/10A61K47/14A61K47/36A61P31/02A61P29/00A61P17/02A61K31/375A61K31/047A61K31/045A61K31/7048A61K31/343A61K31/618
CPCA61K9/0014A61K31/045A61K31/047A61K31/343A61K31/375A61K31/618A61K31/7048A61K33/22A61K36/288A61K47/10A61K47/14A61K47/20A61K47/36A61K2300/00
Inventor 皮定业皮志华周庆良刘莉
Owner CHONGQING LIJIAN SCI & TECH DEV
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