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Antibacterial and anti-inflammatory agent and preparation method thereof

An antibacterial, anti-inflammatory, and medicament technology, which is applied in the direction of anti-inflammatory agents, local antibacterial agents, and pharmaceutical formulations, can solve the problems of rapid healing of tissues that are not easily wounded, and easy dependence and drug resistance, so as to promote wound repair and healing and avoid secondary damage. secondary infection damage, odor-changing effects

Active Publication Date: 2018-08-07
CHONGQING LIJIAN SCI & TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of antibiotic antibacterial agent is prone to dependence and drug resistance, and it is not easy to make wound tissue heal quickly

Method used

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  • Antibacterial and anti-inflammatory agent and preparation method thereof
  • Antibacterial and anti-inflammatory agent and preparation method thereof
  • Antibacterial and anti-inflammatory agent and preparation method thereof

Examples

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preparation example Construction

[0028] The present invention also provides a preparation method of the above-mentioned antibacterial and anti-inflammatory agent, which includes:

[0029] S1: After sodium tetraborate and propylene glycol are mixed evenly by weight parts, then mixed with pure water whose temperature is 80~100°C;

[0030] Mixing sodium tetraborate and propylene glycol first is conducive to the full dispersion of the two, and then mixing with pure water at a temperature of 80-100°C can effectively avoid emulsification.

[0031] In a preferred embodiment of the present invention, the step of mixing sodium tetraborate and propylene glycol includes: mixing sodium tetraborate with a skin penetration enhancer, stirring for 15-25 minutes, then mixing with propylene glycol, and continuing stirring for 15-25 minutes. The addition of a skin penetration enhancer makes the agent more permeable, can quickly penetrate into the deep tissue of the damaged wound, and interact with bacteria to interfere with the...

Embodiment 1

[0041] This embodiment provides an antibacterial and anti-inflammatory agent, and the raw materials of this antibacterial and anti-inflammatory agent include by weight parts:

[0042] 20 parts of ascorbic acid, 20 parts of sodium tetraborate, 10 parts of propylene glycol, 20 parts of glycerin, 1 part of phenoxyethanol, and 60 parts of pure water.

[0043] The preparation method of this medicament is:

[0044] Mix sodium tetraborate and propylene glycol evenly in parts by weight, and then mix with pure water at a temperature of 100°C; then slowly add glycerin and mix evenly, and then slowly add ascorbic acid when the temperature drops to 70°C, and then mix with phenoxyethanol After mixing evenly, an antibacterial solution is obtained, and filtered to obtain the antibacterial and antiphlogistic agent.

Embodiment 2

[0046] This embodiment provides an antibacterial and anti-inflammatory agent, and the raw materials of this antibacterial and anti-inflammatory agent include by weight parts:

[0047] 10 parts of ascorbic acid, 10 parts of sodium tetraborate, 20 parts of propylene glycol, 10 parts of glycerin, 2 parts of phenoxyethanol, and 50 parts of pure water.

[0048] The preparation method of this medicament is:

[0049] Mix sodium tetraborate and propylene glycol evenly in parts by weight, and then mix with pure water at a temperature of 80°C; then slowly add glycerin and mix evenly, and then slowly add ascorbic acid when the temperature drops to 60°C, and then mix with phenoxyethanol After mixing evenly, an antibacterial solution is obtained, and filtered to obtain the antibacterial and antiphlogistic agent.

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Abstract

The present invention relates to the field of wound healing formulations, and provides an antibacterial and anti-inflammatory drug and a preparation method therefor. The antibacterial and anti-inflammatory drug is prepared from the following raw materials: ascorbic acid, sodium tetraborate, propylene glycol, phenoxyethanol, glycerol, and pure water. The preparation method comprises: mixing the sodium tetraborate with the propylene glycol evenly and then mixing with the pure water of 80-100ºC; and slowly adding the glycerol for mixing evenly, lowering the temperature to 60-70ºC, slowly adding the ascorbic acid and then mixing with the phenoxyethanol evenly to obtain an antibacterial liquid and filtering.

Description

technical field [0001] The invention relates to the field of wound repair preparations, in particular to an antibacterial and anti-inflammatory agent and a preparation method thereof. Background technique [0002] Inflammation is a very common and very important pathological process in the human body. It mainly refers to the defensive response of living tissues with vascular system to damage factors composed of bacteria and viruses. Trauma infections on the body surface and most common and frequently-occurring diseases of major organs are inflammatory diseases. [0003] Vascular responses are central to the inflammatory process. Inflammation, which is usually referred to as "inflammation", is a defense response of the body to stimuli, manifested as redness, swelling, heat, pain and functional impairment. In the inflammatory process, on the one hand, damage factors directly or indirectly cause tissue and cell damage, and on the other hand, through inflammatory hyperemia and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K33/22A61K36/288A61K47/20A61K47/10A61K47/14A61K47/36A61P31/02A61P29/00A61P17/02A61K31/375A61K31/047A61K31/045A61K31/7048A61K31/343A61K31/618
CPCA61K9/0014A61K31/045A61K31/047A61K31/343A61K31/375A61K31/618A61K31/7048A61K33/22A61K36/288A61K47/10A61K47/14A61K47/20A61K47/36
Inventor 皮定业皮志华周庆良刘莉
Owner CHONGQING LIJIAN SCI & TECH DEV
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