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Wound dressing with multiple adhesive layers

A technology for wound dressings and adhesives, which can be used in viscous dressings, dressings, synthetic resin layered products, etc., and can solve problems such as high toxicity

Active Publication Date: 2017-08-29
3M INNOVATIVE PROPERTIES CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, some high concentrations of antimicrobials effective in reducing bacteria on the skin are too toxic for the cells needed for wound healing

Method used

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  • Wound dressing with multiple adhesive layers
  • Wound dressing with multiple adhesive layers
  • Wound dressing with multiple adhesive layers

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach A

[0078] Embodiment A is a wound dressing comprising:

[0079] a moisture vapor permeable backing layer having a first major surface, a second major surface, and a backing layer perimeter;

[0080] wherein the second major surface has a first hydrophobic adhesive disposed thereon near the periphery of the backing layer;

[0081] an absorbent hydrophilic adhesive adhered to at least a portion of the second major surface of the backing layer, the absorbent hydrophilic adhesive comprising an absorbent hydrophilic adhesive perimeter;

[0082] an antimicrobial agent disposed in the absorbent hydrophilic binder;

[0083] a porous layer having a first side, a second side, and a porous layer perimeter, the first side being adhered to an absorbent hydrophilic adhesive; and

[0084] a second hydrophobic adhesive adhered to the second side of the porous layer;

[0085] wherein 100% of the perimeter of the absorbent hydrophilic adhesive overlaps the backing layer;

[0086] wherein at le...

Embodiment 1

[0106] Example 1 Preparation of Backing Layer Coated with Hydrophobic Adhesive on One Side .

[0107] Use 23 micron thick 58237 thermoplastic polyurethane film (Lubrizol Corporation, Wickliffe, OH, USA) was used as the backing layer. The film is laminated to have 750mg / 200cm 2 Coat weight of a discontinuous (pattern of holes approximately 1 mm in diameter with 10% of the total open area) acrylate adhesive layer. The film adhesive samples were equilibrated at 25 degrees Celsius and 50% relative humidity. The adhesion value of the sample to steel was measured at 4N / 25mm.

Embodiment 2

[0108] Example 2 Preparation of Backing Layer Adhered to Absorbent Hydrophilic Adhesive .

[0109] A 1.75 mm thick absorbent hydrophilic adhesive was prepared as described in Example 3 of International Publication No. WO 2009 / 091682. Laminate successive layers of absorbent hydrophilic adhesive to a 23 micron thick 58237 Thermoplastic Polyurethane Membrane. The film adhesive samples were equilibrated at 25 degrees Celsius and 50% relative humidity. The adhesion value of the sample to steel was measured at 5.8 N / 25mm.

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Abstract

A wound dressing is provided. The wound dressing includes a moisture-transmissible backing layer having a first major surface, a second major surface, and a backing layer perimeter; an absorbent hydrophilic adhesive adhered to at least a portion of the second major surface of the backing layer, the absorbent hydrophilic adhesive comprising an absorbent hydrophilic adhesive perimeter; an antimicrobial agent disposed in the absorbent hydrophilic adhesive; a porous layer having a first side adhered to the absorbent hydrophilic adhesive, a second side, and a porous layer perimeter; and a second hydrophobic adhesive adhered to the second side of the porous layer. The second major surface has a first hydrophobic adhesive disposed thereon proximate the backing layer perimeter. 100% of the absorbent hydrophilic adhesive perimeter is overlapped by the backing layer. At least 50% of the porous layer perimeter is overlapped by the absorbent hydrophilic adhesive.

Description

[0001] Cross References to Related Applications [0002] This patent application claims priority to U.S. Provisional Patent Application No. 62 / 098,058, filed December 30, 2014, and U.S. Provisional Patent Application No. 62 / 112,714, filed February 6, 2015, the disclosures of which are set forth in their entirety as Incorporated herein by reference. Background technique [0003] Transparent film dressings are widely used as a protective layer to cover wounds because they facilitate recovery in moist environments and serve as a barrier against contaminating fluids and bacteria. The films are also useful as surgical drapes by virtue of their barrier properties. Dressings and drapes conforming to the above description are available under various trade names such as TEGADERM TM (3M Company, St. Paul, MN, USA), BIOCLUSIVE TM (Johnson & Johnson Company, New Brunswick, NJ, USA) and OP-SITE TM (T.J. Smith & Nephew, Hull, England). [0004] Additionally, the length of time a medic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/02A61L15/42A61L15/46A61L15/60
CPCA61F13/0253A61L15/425A61L15/46A61L15/60A61F13/022A61F13/05A61L2300/404A61L15/58B32B2262/0292B32B2556/00B32B2307/546B32B3/266B32B27/40B32B2307/542B32B2255/10B32B2307/51B32B2255/26B32B27/285B32B27/34B32B2307/412B32B25/10B32B27/36B32B25/14B32B2270/00B32B2307/728B32B25/08B32B2307/726B32B7/12B32B2307/724B32B7/14B32B2266/06B32B7/08B32B25/042B32B2535/00B32B25/045B32B2307/73B32B2307/72B32B2255/02B32B7/04B32B2307/558B32B2307/718B32B2266/0278B32B27/12B32B27/08B32B3/26B32B27/06B32B2250/44B32B5/245B32B2307/732B32B5/32B32B2262/04B32B2307/7145B32B2307/7265B32B2262/0276B32B5/026B32B5/26B32B5/022B32B5/024B32B27/065B32B5/18A61P17/00A61P17/02C08L39/06B32B3/00A61F13/00063A61F13/0206A61F13/0266A61L15/22A61L15/44A61L15/24A61L15/26
Inventor 戴维·R·霍尔姆西蒙·S·冯詹姆斯·M·夏拉基
Owner 3M INNOVATIVE PROPERTIES CO