Method for extracting and separating 6-gingerol from ginger

A gingerol and ginger technology, applied in the field of ginger extract extraction, can solve the problems of unstable physical and chemical properties, loss of activity, and low purity of 6-gingerol, and achieve no reduction in biological activity, high biological activity, and high yield Effect
CN107151202AInactive Publication Date: 2017-09-12HUNAN UNIV OF SCI & ENG
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HUNAN UNIV OF SCI & ENG
Publication Date
2017-09-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method for extracting and separating 6-gingerol from ginger. The method comprises the following operation steps: solvent extracting, low-pressure silica gel column chromatography separation, high performance liquid chromatography purification and recrystallization. The yield of the 6-gingerol prepared by the method is high; the prepared 6-gingerol is high in biological activity and high in purity, and can be directly used for preparing drugs; the 6-gingerol can be stored in cryoprotectant for a long time; and the biological activity of the 6-gingerol is not reduced.
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Description

technical field

[0001] The present invention relates to a kind of extracting method of ginger extract, particularly a kind of method for extracting and separating 6-gingerol from ginger. Background technique

[0002] There are a series of gingerol homologues in ginger. Due to their similar structure and similar properties, it is difficult to purify them into monomer components by conventional methods. The components separated on the low-pressure column chromatography column are identified as single spots by thin-layer chromatography. In fact, it is a family of compounds. After further separation by high performance liquid chromatography, 5 compounds are obtained, and one of the main components is 6-gingerol. Containing 8-hydroxyketone structure in 6-gingerol, its physical and chemical properties are unstable, and it is easily disturbed by external conditions and loses its activity. At present, the extraction method of 6-gingerol mostly adopts the method of chemical extracta...

Claims

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