Production method of medical artificial skin

A technology of artificial skin and production method, applied in medical science, prosthesis, etc., can solve the problems of incomplete safety guarantee, complex and cumbersome preparation process, residual organic solvents, etc., achieve shortened preparation cycle and good skin biocompatibility , no harm to human body and environment

Inactive Publication Date: 2017-11-21
江西高大生物医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After testing, the porous silicon rubber film prepared by this method has a smaller pore size, although it can resist the invasion of external bacteria to a certain extent, but the gas permeability is not strong; Long, low production efficiency; at the same time, a series of orga

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0024] Example 1

[0025] A production method of medical artificial skin specifically includes the following steps:

[0026] A. According to the mass percentage, take 65% injection addition molding liquid silicone rubber A component and 35% purified water, mix and stir uniformly at room temperature, and the stirring speed is 1500r / min to obtain mixture 1.

[0027] B. According to the mass percentage, take 65% injection-addition liquid silicone rubber B component and 35% purified water, mix and stir uniformly at room temperature, the stirring speed is 1500r / min, to obtain mixture 2.

[0028] C. According to the mass percentage, take 50% mixture one and 50% mixture two, mix and stir uniformly at room temperature, and the stirring speed is 500r / min to obtain mixture three.

[0029] D. The mixture is fed into the salivator for three times to form a film, and the film is cured after the film is formed. The curing temperature is 70°C and the curing time is 35 minutes. After curing, it is evap...

Example Embodiment

[0032] Example 2

[0033] A production method of medical artificial skin specifically includes the following steps:

[0034] A. According to the mass percentage, take 70% injection-addition liquid silicone rubber component A and 30% purified water, mix and stir uniformly at room temperature, and the stirring speed is 2300r / min to obtain mixture 1.

[0035] B. According to the mass percentage, take 70% injection-addition liquid silicone rubber B component and 30% purified water, mix and stir uniformly at room temperature, the stirring speed is 2300r / min, to obtain mixture 2.

[0036] C. According to the mass percentage, take 50% mixture one and 50% mixture two, mix and stir uniformly at room temperature, and the stirring speed is 500r / min to obtain mixture three.

[0037] D. Input the mixture into a salivator for three times to form a film. After the film is formed, it is cured. The curing temperature is 80°C and the curing time is 30 minutes. After curing, it is evaporated again. The ev...

Example Embodiment

[0040] Example 3

[0041] A production method of medical artificial skin specifically includes the following steps:

[0042] A. According to the mass percentage, take 75% injection-addition liquid silicone rubber component A and 25% purified water, mix and stir uniformly at room temperature, and the stirring speed is 3000r / min to obtain mixture 1.

[0043] B. According to the mass percentage, take 75% injection-addition liquid silicone rubber B component and 25% purified water, mix and stir uniformly at room temperature, and the stirring speed is 3000r / min to obtain mixture 2.

[0044] C. According to the mass percentage, take 50% mixture one and 50% mixture two, mix and stir uniformly at room temperature, and the stirring speed is 500r / min to obtain mixture three.

[0045] D. Enter the mixture into a salivator for three times to form a film. After the film is formed, the film is cured. The curing temperature is 90°C and the curing time is 25 minutes. After curing, it is evaporated agai...

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PUM

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Abstract

The invention discloses a production method of a medical artificial skin. The method comprises the following steps: according to steps A-E, feeding a component A and a component B of injecting and forming liquid silicone rubber according to a certain mass ratio under a certain condition, separately mixing the component A and the component B with purified water uniformly at first, then mixing the component A and the component B uniformly under a certain condition, feeding the mixture into a slobbering machine and carrying out slobbering film forming, curing and evaporating at the specifically selected temperature and for a specifically selected time, and then carrying out steps such as puncturing, slitting and rolling to obtain the finished medical artificial skin. The method is simple, convenient and practical, is short in preparation period and high in efficiency, does not use organic solvents in a production process, is safe and environmentally friendly, meanwhile can provide a wet environment for a wound to facilitate healing of the wound, and is not adhered to the wound when used, so that pain of a patient when the medical artificial skin is changed is relieved; and moreover, the produced medical artificial skin is good in resistance of bacteria and breathability.

Description

technical field [0001] The invention belongs to the field of preparation of medical polymer materials, and in particular relates to a production method of medical artificial skin. Background technique [0002] The skin is the outermost structure of the human body and the largest organ of the human body. It is not only a sensory organ of the nervous system, but also an effector. Mechanical and chemical stimuli such as cold, heat, pain, and emotional changes all reflexively cause skin vasoconstriction and relaxation, arrector pili muscle contraction, sweat gland secretion, and skin capillary permeability. sexual change. The skin covers the whole body, and it protects various tissues and organs in the body from physical, mechanical, chemical and pathogenic microorganisms. [0003] The skin is a natural barrier to protect the body. For patients with severe skin defects, a large amount of body fluid loss and wound infection are the main factors that threaten the lives of patien...

Claims

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Application Information

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IPC IPC(8): A61L27/60A61L27/18A61L27/08A61L27/02
CPCA61L27/025A61L27/08A61L27/18A61L27/60C08L83/04
Inventor 郭勇夏和生罗高兴李雪波何显文曾凡平
Owner 江西高大生物医疗科技有限公司
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