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Vitiligo Uighur medicine compound and preparation method thereof

A vitiligo, compound technology, applied in the direction of pharmaceutical formulas, drug combinations, medical preparations containing active ingredients, etc., can solve problems such as the decline of antiviral ability, and achieve quick effect, exact curative effect, no drug resistance and physical dependence. Effect

Active Publication Date: 2017-11-24
XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, when suffering from diabetes, hyperthyroidism, psoriasis, lupus erythematosus, alopecia areata and other diseases, the body's own natural force is weakened and the normal physiological function of the liver is destroyed, which causes excessive production of abnormal body fluids, and the overall anti-virus ability of the body decreases. Vitiligo is caused by the fourth digestion that cells do not function properly

Method used

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  • Vitiligo Uighur medicine compound and preparation method thereof
  • Vitiligo Uighur medicine compound and preparation method thereof
  • Vitiligo Uighur medicine compound and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Prepare tinctures based on 1000ml:

[0028] Table 1 embodiment prescription ratio

[0029]

[0030] a. Mix the screened raw medicinal materials Nigella seed, madder root, insect repellent Vernonia, clove, fig leaf and anarch root according to the formula ratio given in Table 1, and use 30 times the concentration of 95 % ethanol extraction, the temperature is the boiling point of the solvent, extraction 1 time, time 6 hours, filtration, recovery of ethanol under reduced pressure, to obtain liquid extract, for subsequent use;

[0031] B, add ethanol to the liquid extract obtained in step a, make 70% tincture (every 100ml is equivalent to 10g~20g of former decoction pieces), surplus is water, packs every bottle 100mL, 200mL, makes tincture.

Embodiment 2

[0033] Prepare tinctures based on 1000ml:

[0034] a. Mix the screened medicinal materials Nigella seed, madder root, insect repelling Vernonia, clove, fig leaf and anarch root according to the formula ratio given in Table 1, and use 20 times the concentration of 75% Ethanol extraction, the temperature is the boiling point of the solvent, extraction 2 times, each extraction is 2 hours, filtered, the combined filtrate is reduced in pressure to recover ethanol, and the liquid extract is obtained for subsequent use;

[0035] B, add ethanol to the liquid extract obtained in step b, make 90% tincture (every 100ml is equivalent to 10g~20g of former decoction pieces), surplus is water, packs every bottle 100mL, 200mL, makes tincture.

Embodiment 3

[0037] Prepare tinctures based on 1000ml:

[0038] a. Mix the screened medicinal materials Nigella seed, madder root, insect repelling Vernonia, clove, fig leaf and anarch root according to the formula ratio given in Table 1, and use 5 times the concentration of 10% Ethanol extraction, the temperature is the boiling point of the solvent, extraction 3 times, 3 hours each time, filtering, combining the filtrate to recover ethanol under reduced pressure, to obtain a liquid extract, for subsequent use;

[0039] B, add ethanol to the liquid extract obtained in step b, make 30% tincture (every 100ml is equivalent to 10g~20g of former decoction pieces), surplus is water, packs every bottle 100mL, 200mL, makes tincture.

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Abstract

The invention relates to a vitiligo Uighur medicine compound and a preparation method thereof. The compound is prepared from fennelflower seed, madder root, vernonia anthelmintica fruit, syzygium aromaticum flower, leaf of common fig, anacyclus pyrethrum root and other medicinal materials. Tinctures and gels are prepared by solvent extraction and pharmaceutical adjuvant. The vitiligo Uighur medicine compound is obtained by inheriting medication features of Uighur medicine under the guidance of a Uighur medicine theory via a modern extraction method according to long-term folk clinical practices of Uighur, thereby ensuring the content of effective components, and improving the bioavailability. The vitiligo Uighur medicine compound has the functions of adjusting abnormal phlegmatic temperament, invigorating the circulation of blood to color, and is used for treating vitiligo and leukoderma. In-vitro activity indicates that the vitiligo Uighur medicine compounds with different components have strong cell melanin growth activity. Pharmacological results show that the vitiligo Uighur medicine compound can be used for treating vitiligo at different extents.

Description

technical field [0001] The invention relates to a Uighur medicine compound prescription for vitiligo and a preparation method thereof, belonging to the technical field of Uighur medicine and ethnic medicine. Background technique [0002] Vitiligo is a common skin depigmentation disease caused by the reduction or loss of functional melanocytes in the skin and / or hair follicles. The prevalence of this disease in the world is 0.5%-2%. The main symptom is localized or generalized skin leukoplakia caused by a large area of ​​melanin loss. Although this disease does not cause fatal harm to the human body, it seriously affects patients. appearance and normal social activities and bring mental stress to patients. At present, the pathogenesis of vitiligo has not been fully elucidated, but more and more studies support that there is a close relationship between vitiligo and abnormal immune response. Under the action of genetic factors and environmental stimuli, the normal skin immune...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P17/00
CPCA61K36/28A61K36/60A61K36/61A61K36/71A61K36/74A61K2236/333A61K2236/39A61K2300/00
Inventor 阿吉艾克拜尔·艾萨阿卜力克木·奥布力罗玉琴希尔艾力·吐尔逊
Owner XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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