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A kind of pharmaceutical composition for treating gastric ulcer and duodenal ulcer

A duodenal ulcer and composition technology, which is applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of affecting the absorption of active ingredients in compound preparations, weak gastrointestinal absorption function, aggravating the gastrointestinal burden of patients, etc. The effect of recurrence rate, inhibition of gastric acid secretion, and rapid control of patient symptoms

Active Publication Date: 2020-11-10
ZHENGZHOU TAIFENG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the compound preparation provided by this patent can basically take into account the advantages of both Chinese and Western medicines, a large number of skeleton materials are used in the patent composition, which is not suitable for patients with gastric ulcer and duodenal ulcer. The reason is that such patients The gastrointestinal absorption function is inherently weak. Such a large amount of skeleton materials not only affects the absorption of the active ingredients in the compound preparation, but also increases the burden on the patient’s gastrointestinal tract; People with deficiency and cold should not take it. However, there are many patients with gastric ulcer and duodenal ulcer who have spleen and stomach deficiency.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 125g of squid octopus (floating) is crushed into powder, and passed through a 100-mesh sieve;

[0031] 450g of licorice (honey), 375g of white peony root, 200g of Corydalis (vinegar), 200g of Codonopsis pilosula and 175g of Citrus aurantium (stir-fried with bran). The decoction is filtered and concentrated into an extract with a relative density of 1.34-1.39 (55-60°C);

[0032] Add the above-mentioned squid octopus (bleach) powder to the above-mentioned extract, mix well, spray dry, grind into powder, pass through a 80-mesh sieve to obtain Chinese medicine powder, add appropriate amount of water to make soft material, pass through a 18-24 mesh sieve, and prepare Form into wet granules, dry at 55°C, pass through a 18-24 mesh sieve for granulation, and obtain traditional Chinese medicine granules;

[0033] Add 20g of omeprazole enteric-coated pellets to the above-mentioned traditional Chinese medicine granules, mix evenly, pack into capsules, and make 1000 capsules to ob...

Embodiment 2

[0036] 125g of squid octopus (floating) is crushed into powder, and passed through a 100-mesh sieve;

[0037] 450g of licorice (made from honey), 375g of white peony root, 200g of corydalis (made from vinegar), 200g of Codonopsis pilosula and 175g of five-flavored medicinal materials of Citrus aurantium (stir-fried with bran). liquid, filtered, and concentrated under reduced pressure to an extract of 1.10-1.15 (55-60°C);

[0038] Add the above-mentioned squid octopus (bleach) powder to the above-mentioned extract, mix well, spray dry, grind into powder, pass through a 80-mesh sieve to obtain Chinese medicine powder, add appropriate amount of water to make soft material, pass through a 18-24 mesh sieve, and prepare Form into wet granules, dry at 55°C, pass through a 18-24 mesh sieve for granulation, and obtain traditional Chinese medicine granules;

[0039] Add 20 g of omeprazole enteric-coated microparticles to the above-mentioned traditional Chinese medicine granules, mix ev...

Embodiment 3

[0041] 100g of squid octopus (floating) is crushed into powder, and passed through a 100-mesh sieve;

[0042]400g of licorice (made from honey), 350g of white peony root, 150g of corydalis (made from vinegar), 150g of Codonopsis pilosula, 150g of citrus aurantium (stir-fried with bran) and 150g of five herbs. liquid, filtered, and concentrated into an extract with a relative density of 1.34-1.39 (55-60°C);

[0043] Add the above-mentioned squid octopus (bleach) powder to the above-mentioned extract, mix well, dry, pulverize into powder, pass through a 80-mesh sieve to obtain a Chinese medicine powder, add appropriate amount of water to make a soft material, and pass through a 18-24 mesh sieve to make a wet powder. The granules were dried at 55°C, passed through a 18-24 mesh sieve, and granulated to obtain traditional Chinese medicine granules;

[0044] Add 19g of omeprazole enteric-coated pellets to the above-mentioned traditional Chinese medicine granules, mix evenly, pack i...

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PUM

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Abstract

The invention provides a medicinal composition for treating gastric ulcer and duodenal ulcer. The medicinal composition is prepared from 18-22 g of omeprazole, 300-600 g of licorice root, 250-500 g of white peony root, 100-300 g of Rhizoma Corydalis, 50-200 g of cuttlebones, 100-300 g of Radix Codonopsis and 100-250 g of Fructus Aurantii. The medicinal composition has practicable and effective effects on the gastric ulcer and duodenal ulcer, and can maximally reduce the repeated attack of the gastric ulcer and duodenal ulcer in order to reach the purpose of treating both manifestation and root cause of diseases.

Description

technical field [0001] The invention belongs to the technical field of compound preparations, in particular to a pharmaceutical composition for treating gastric ulcer and duodenal ulcer. Background technique [0002] The formation of gastric ulcer and duodenal ulcer is related to the digestion of gastric acid and pepsin, so it is called peptic ulcer. About 10% of the population may suffer from this disease in their lifetime, so it is a frequently-occurring and common disease and plays an important role in the Department of Gastroenterology. The etiology of gastric ulcer and duodenal ulcer is complex, including genetic factors, chemical factors, life factors, mental factors, infection factors, etc. They are common in people with irregular diet, high work pressure, and mental stress. In addition, long-term smoking and drinking are also huge incentives . Most patients with gastric ulcer and duodenal ulcer have recurrent attacks, and the attack period and remission period alte...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P1/04A61K35/618A61K31/4439
CPCA61K31/4439A61K35/618A61K36/344A61K36/484A61K36/65A61K36/66A61K36/71A61K36/752A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 沙薇黄普广李婷郑海杰
Owner ZHENGZHOU TAIFENG PHARMA CO LTD
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