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Composition for lowering blood sugar and blood pressure

A composition and hypoglycemic technology, applied in the directions of drug combinations, plant raw materials, cardiovascular system diseases, etc., can solve the problems of disappearance, unabated drug effect, and reduced drug effect.

Active Publication Date: 2018-01-16
北京中科上医中医学研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] After research, the applicant found that Huoshan Dendrobium powder does not have the effect of lowering blood pressure and blood sugar. However, when doing experiments on mice, it was found that certain components of Huoshan Dendrobium had the effect of lowering blood pressure and blood sugar. However, the extracted The active substances of Huoshan Dendrobium candidum are unstable, and after a period of time, the efficacy will decrease or even disappear. , to provide a valuable shelf life from production to sales, the present invention proposes a composition with the function of lowering blood pressure and blood sugar, which can be stored for 30 days for a long time without reducing the efficacy

Method used

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  • Composition for lowering blood sugar and blood pressure
  • Composition for lowering blood sugar and blood pressure

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] In this example, a natural product capable of lowering blood pressure and blood sugar in mice was obtained by extracting and removing interfering substances multiple times, and retaining components that are effective in lowering blood pressure and blood sugar. The preparation method is as follows:

[0023] 1) drying the stems and leaves of three-year-old Dendrobium officinale at a temperature lower than 45°C until the water content is less than 8%, and crushing the fresh stems and leaves of Dendrobium officinale with a pulverizer after drying to obtain stems and leaves of Dendrobium officinale dry powder;

[0024] 2) Take 100g of stem and leaf dry powder of Dendrobium nobile, add 6g of ammonium oxalate to it, dilute to 1L with 50% ethanol solution, conduct ultrasonic extraction at 40°C and ultrasonic power of 300w for 45min, separate the material and liquid after the extraction is completed, and obtain the extracted Liquid I and Precipitate I.

[0025] 3) Add 0.3% sodi...

Embodiment 2

[0037] In this example, a natural product capable of lowering blood pressure and blood sugar in mice was obtained by extracting and removing interfering substances multiple times, and retaining components that are effective in lowering blood pressure and blood sugar. The preparation method is as follows:

[0038] 1) drying the stems and leaves of three-year-old Dendrobium officinale at a temperature lower than 45°C until the water content is less than 8%, and crushing the fresh stems and leaves of Dendrobium officinale with a pulverizer after drying to obtain stems and leaves of Dendrobium officinale dry powder;

[0039] 2) Take 50g of stem and leaf dry powder of Dendrobium nobile, add 3g of ammonium oxalate to it, dilute to 1L with 45% ethanol solution, conduct ultrasonic extraction at 50°C and ultrasonic power of 80w for 120min, separate the material and liquid after the extraction is completed, and obtain the extracted Liquid I and Precipitate I.

[0040] 3) Add 0.01% sodi...

Embodiment 3

[0047] In this example, a natural product capable of lowering blood pressure and blood sugar in mice was obtained by extracting and removing interfering substances multiple times, and retaining components that are effective in lowering blood pressure and blood sugar. The preparation method is as follows:

[0048] 1) drying the stems and leaves of three-year-old Dendrobium officinale at a temperature lower than 45°C until the water content is less than 8%, and crushing the fresh stems and leaves of Dendrobium officinale with a pulverizer after drying to obtain stems and leaves of Dendrobium officinale dry powder;

[0049] 2) Take 200g stem and leaf dry powder of Dendrobium nobile, add 10g ammonium oxalate to it, dilute to 1L with 60% ethanol solution, conduct ultrasonic extraction at 30°C and ultrasonic power 345w for 30min, separate the material and liquid after the extraction is completed, and obtain the extracted Liquid I and Precipitate I.

[0050] 3) Add 1% sodium ascorba...

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Abstract

The invention provides a composition for lowering blood sugar and blood pressure, belonging to the technical field of natural materials for lowering blood sugar and blood pressure. The composition forlowering the blood sugar and the blood pressure is prepared from the following components: dendrobium ammonium oxalate ethyl alcohol extract, dendrobium n-butanol extract, L-ascorbic acid, beta-carotene, resistant starch, tea polyphenol-palmitate, potassium sorbate and vegetable oil. The composition effectively ensures the activity of the dendrobium ammonium oxalate ethyl alcohol extract and thedendrobium n-butanol extract. The composition still has high medicine effect after being stored for 30 days at normal temperature. The composition solves a problem of long-term storage of the dendrobium ammonium oxalate ethyl alcohol extract and the dendrobium n-butanol extract, and has extremely high market value.

Description

Technical field: [0001] The invention belongs to the technical field of compositions for lowering blood sugar and blood sugar, in particular to a composition for lowering blood sugar and blood sugar. Background technique: [0002] Dendrobium officinale (scientific name: Dendrobium officinale Kimura et Migo): erect stem, cylindrical, 9-35 cm long, 2-4 mm thick, unbranched, multi-noded; leaves two rows, papery, oblong-lanceolate , margins and ribs often tinged with lavender. Racemes often emanate from the upper part of old stems that have fallen leaves, with 2-3 flowers; bracts dry membranous, light white, ovate, 5-7 mm long, sepals and petals yellow-green, nearly similar, oblong lanceolate, lip white, with a green or yellow callus at the base, ovate-lanceolate, slightly shorter than sepals, reflexed in the middle. Stamens yellow-green, about 3mm long, with 1 purple spot on both sides of apex; medicine cap white, long ovate-triangular, about 2.3mm long, apex subacute and 2-l...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61K47/44A61K47/36A61K47/22A61K47/12A61P3/10A61P9/12
Inventor 陈乃富孙传伯韩邦兴陈存武
Owner 北京中科上医中医学研究院
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