Hydrogel sour pomegranate powder skin care product as well as preparation method and application thereof

A technology of hydrogel sour pomegranate and skin care products, which is applied in the medical field, can solve the problems of loss of useful ingredients, high sugar content, and increased costs, and achieve high biocompatibility, simple production process, and gel stability.

Active Publication Date: 2018-03-06
QUFU NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It not only increases the cost, but also causes the loss of many useful ingredients in the process of extracting ingredients; directly using pomegranate juice to make skin care products will cause higher sugar content, which will also limit its application

Method used

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  • Hydrogel sour pomegranate powder skin care product as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 1) Take each raw material according to the proportion, add poly-γ-glutamic acid into sterilized deionized water, stir and dissolve, prepare a transparent solution of 0.08g / mL, and take 5mL for later use;

[0030] 2) Weigh 0.04g of hyaluronic acid and add it to the poly-γ-glutamic acid solution in step 1), and stir evenly to form a poly-γ-glutamic acid solution rich in hyaluronic acid.

[0031] 3) Weigh 0.05g chitosan oligosaccharide and add it to the poly-γ-glutamic acid solution rich in hyaluronic acid in step 2), stir evenly to form a homogeneous solution;

[0032] 4) Microwave the homogeneous solution in step 3) for 15s, and continue to stir until a clear and transparent solution is formed;

[0033] 5) Cool the clear and transparent solution prepared in step 4) to room temperature and set aside;

[0034] 6) Add sour pomegranate juice powder into sterilized deionized water, stir for 5 minutes, mix well, and prepare 0.5mg / mL sour pomegranate juice solution;

[0035] ...

Embodiment 2

[0040] 1) Take each raw material according to the ratio, add poly-γ-glutamic acid into sterilized deionized water, stir and dissolve, prepare a transparent solution of 0.12g / mL, and take 5mL for later use;

[0041] 2) Weigh 0.04g of hyaluronic acid and add it to the poly-γ-glutamic acid solution in step 1), and stir evenly to form a poly-γ-glutamic acid solution rich in hyaluronic acid.

[0042] 3) Weigh 0.05g chitosan oligosaccharide and add it to the poly-γ-glutamic acid solution rich in hyaluronic acid in step 2), stir evenly to form a homogeneous solution;

[0043] 4) Microwave the homogeneous solution in step 3) for 15s, and continue to stir until a clear and transparent solution is formed;

[0044] 5) Cool the clear and transparent solution prepared in step 4) to room temperature and set aside;

[0045] 6) Add sour pomegranate juice powder into sterilized deionized water, stir for 5 minutes, mix well, and prepare 0.5mg / mL sour pomegranate juice solution;

[0046] 7) Ta...

Embodiment 3

[0051] 1) Take each raw material according to the ratio, add poly-γ-glutamic acid into sterilized deionized water, stir and dissolve, prepare a transparent solution of 0.16g / mL, and take 5mL for later use;

[0052] 2) Weigh 0.04g of hyaluronic acid and add it to the poly-γ-glutamic acid solution in step 1), and stir evenly to form a poly-γ-glutamic acid solution rich in hyaluronic acid.

[0053] 3) Weigh 0.05g chitosan oligosaccharide and add it to the poly-γ-glutamic acid solution rich in hyaluronic acid in step 2), stir evenly to form a homogeneous solution;

[0054] 4) Microwave the homogeneous solution in step 3) for 15s, and continue to stir until a clear and transparent solution is formed;

[0055] 5) Cool the clear and transparent solution prepared in step 4) to room temperature and set aside;

[0056] 6) Add sour pomegranate juice powder into sterilized deionized water, stir for 5 minutes, mix well, and prepare 0.5mg / mL sour pomegranate juice solution;

[0057] 7) Ta...

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Abstract

The invention relates to a hydrogel sour pomegranate powder skin care product as well as a preparation method and application thereof. The hydrogel sour pomegranate powder skin care product is prepared from raw materials, namely poly gamma-glutamic acid, chitosan oligosaccharide, hyaluronic acid and a cross-linking agent EDC / NHS, rhamnolipid and sour pomegranate powder through steps of jucing, purification, freeze drying and extraction. The hydrogel sour pomegranate powder skin care product provided by the invention is good in biocompatibility, antibacterial property, efficient moistening property and skin whitening property. As hydrogel is preferably adopted as a skin care product matrix, and the sour pomegranate powder is adopted as an active component, the skin care product is relatively good in water retention property, relatively low in water loss rate, good in skin whitening function and relatively good in biodegradability; in addition the raw materials are cheap and easy to obtain, only a small amount of chemical substance products are used, and the components are mostly degradable macromolecule polymers generated from microorganisms instead, so that the product is environmentally friendly, free of toxic or side effect and simple in production process, and on-batch production can be implemented.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a skin care product with hydrogel as a base and pomegranate acid powder as an active ingredient, its preparation method and application. Background technique [0002] Sour pomegranate is a sour fruit of the pomegranate family. Sour pomegranate juice is a healthy drink made from sour pomegranate. It is rich in various trace elements needed by the human body and has health care effects. [0003] Sour pomegranate juice is rich in vitamin C and vitamin B, organic acids, sugars, proteins, fats, and trace elements, etc. It has various functions such as anti-oxidation, scavenging free radicals, and delaying human aging; Alkali, so that it has a broad-spectrum antibacterial activity; contains a variety of plant polyphenols, which have anti-ultraviolet, whitening and moisturizing properties; the fruit acid contained in it can achieve the moisturizing effect of the mask, and h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/88A61K8/73A61K8/60A61K8/04A61Q17/00A61Q19/00A61Q19/02
CPCA61K8/042A61K8/60A61K8/735A61K8/736A61K8/88A61K8/97A61K2800/84A61Q17/005A61Q19/00A61Q19/02
Inventor 车程川梁鑫鑫杨革李媛巩志金刘金锋
Owner QUFU NORMAL UNIV
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