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Medicinal composition for treating poliomyelitis

A technology of composition and medicine, which is applied in the direction of medical formula, plant raw materials, and diseases transmitted by vectors, can solve problems such as obvious side effects, harm to children, and single effect, and achieve small side effects, save labor and cost, and cause little harm Effect

Inactive Publication Date: 2018-03-09
周丽
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most of the medicines for the treatment of polio on the market are single in effect, expensive, and have obvious side effects, which are harmful to children. Therefore, it is urgent to research and develop a compound medicine for treating polio with good curative effect, low cost and little side effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Party:

[0017] 48 parts of cocklebur, 55 parts of perilla, 15 parts of trichosanthes, 15 parts of Digupi, 10 parts of cassia, 2 parts of loquat leaves, 3 parts of alum, 2 parts of sodium carboxymethylcellulose, 1 part of dextrin, Glycine 1 part.

[0018] Preparation:

[0019] (1) Weigh the above raw materials according to the formula ratio, crush the dried cocklebur and perilla through a 100-mesh sieve, and then soak them in 70% ethanol for 1 hour. After all the ethanol volatilizes, add 2 times cocklebur The distilled water of weight of perilla and perilla is heated and boiled, filtered after cooling, and concentrate A is obtained after the filtrate is concentrated for subsequent use;

[0020] (2) Grind the trichosanthes, Digupi, Cassia, and loquat leaves after drying, pass through a 50-mesh sieve, add distilled water twice the total weight of the trichosanthes, Digupi, Cassia, and loquat leaves, heat to boil, and cool After filtering, the filtrate was concentrated ...

Embodiment 2

[0024] Party:

[0025] 65 parts of cocklebur, 70 parts of perilla, 25 parts of trichosanthes, 20 parts of Digupi, 15 parts of cassia, 4 parts of loquat leaves, 5 parts of alum, 2 parts of sodium carboxymethylcellulose, 1 part of dextrin, Glycine 1 part.

[0026] Preparation:

[0027] (1) Weigh the above raw materials according to the formula ratio, crush the dried cocklebur and perilla through a 120-mesh sieve, and then soak them in 80% ethanol for 3 hours. After all the ethanol volatilizes, add 4 times cocklebur The distilled water of weight of perilla and perilla is heated and boiled, filtered after cooling, and concentrate A is obtained after the filtrate is concentrated for subsequent use;

[0028] (2) Grind the trichosanthes, Digupi, Cassia, and loquat leaves after drying, pass through a 60-mesh sieve, add distilled water three times the total weight of the trichosanthes, Digupi, Cassia, and loquat leaves, heat to boil, and cool After filtering, the filtrate was concen...

Embodiment 3

[0032] Party:

[0033] 56 parts of cocklebur, 62 parts of perilla, 20 parts of trichosanthes, 18 parts of Digupi, 12 parts of cassia, 3 parts of loquat leaves, 4 parts of alum, 2 parts of mannitol, 1 part of dextrin, and 1 part of glycine.

[0034] Preparation:

[0035] (1) Weigh the above raw materials according to the formula ratio, crush the dried cocklebur and perilla through a 110-mesh sieve, and then soak them in 75% ethanol for 2 hours. After the ethanol is completely volatilized, add 3 times of cocklebur The distilled water of weight of perilla and perilla is heated and boiled, filtered after cooling, and concentrate A is obtained after the filtrate is concentrated for subsequent use;

[0036] (2) Grind TCS, Digupi, Cassia, and Loquat leaves after drying, pass through a 55-mesh sieve, add distilled water twice the total weight of TCM, Digupi, Cassia, and Loquat leaves, heat to boil, and cool After filtering, the filtrate was concentrated to obtain concentrate B for s...

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PUM

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Abstract

The invention discloses a medicinal composition for treating poliomyelitis. The medicinal composition for treating the poliomyelitis is mainly prepared from the raw materials in parts by weight: 48 to65 parts of fructus xanthii, 55 to 70 parts of perilla nankinensis, 15 to 25 parts of radix trichosanthis, 15 to 20 parts of cortex lycii radicis, 10 to 15 parts of semen cassiae torae, 2 to 4 partsof folium eriobotryae and 3 to 5 parts of potassium alum. Compared with the prior art, the medicinal composition can effectively treat poliomyelitis, and is low in cost, low in side effect, and has little harm to children; meanwhile, a preparation method is simple; manpower and cost are reduced; raw materials can be utilized to the utmost extent; the bioavailability is improved.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating polio. Background technique [0002] Polio generally refers to poliomyelitis. Poliomyelitis is an acute infectious disease caused by poliovirus that seriously endangers children's health. Poliovirus is a neurotropic virus that mainly invades the motor nerve cells of the central nervous system. Anterior horn motor neuron damage is dominant. Most of the patients are children aged 1 to 6. The main symptoms are fever, general discomfort, severe limb pain, and flaccid paralysis with irregular distribution and varying severity, commonly known as polio. The clinical manifestations of poliomyelitis are varied and include very mild nonspecific lesions, aseptic meningitis (nonparalytic poliomyelitis), and flaccid weakness of various muscle groups (paralytic poliomyelitis). In patients with poliomyelitis, due to the damage to the motor neurons in th...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P31/14A61K33/06
CPCA61K33/06A61K36/21A61K36/28A61K36/428A61K36/482A61K36/535A61K36/73A61K36/815A61K2236/331A61K2236/333A61K2236/51A61K2300/00Y02A50/30
Inventor 周丽
Owner 周丽
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