Bone cement as well as preparation method and application thereof

A technology of bone cement and calcium phosphate bone cement, which is applied in the field of medical materials and can solve the problems of not being able to meet the clinical needs of vertebral body compression fractures
CN107899073AActive Publication Date: 2018-04-13PEKING UNIV FIRST HOSPITAL
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
PEKING UNIV FIRST HOSPITAL
Publication Date
2018-04-13

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Abstract

The invention relates to bone cement as well as a preparation method and application thereof. The bone cement is prepared from 50 to 92 weight percent of alpha-tricalcium phosphate, 3 to 10 weight percent of dicalcium phosphate dihydrate, 2 to 30 weight percent of starch and 0.5 to 15 weight percent of nano-silver loaded diatomite. The bone cement disclosed by the invention has the advantages of injection, antibacterial property and degradability, and can be used for treating vertebral compression fracture caused by osteoporosis induced by glucocorticoid.
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Description

technical field

[0001] The present invention relates generally to the field of medical materials, and more particularly to bone cements, their preparation methods and uses. Background technique

[0002] Percutaneous vertebroplasty is a common method for the treatment of osteoporotic vertebral compression fractures. The medical bone cement used is generally non-degradable polymethyl methacrylate (PMMA) material. PMMA is a biologically inert material that cannot form an organic chemical interface with the host bone tissue. In addition, the heat generated during the solidification polymerization process, the cytotoxicity of the monomer, and the limited operability time also limit its clinical application.

[0003] There are other types of bone cements in the prior art, such as calcium phosphate bone cement and calcium sulfate bone cement. For example, Chinese patent application CN 104857568A discloses antibacterial calcium sulfate-based bone cement and its preparation method,...

Claims

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