Preparation method of composite bone reconstruction scaffold with bone tumor resistance

Abstract

The invention discloses a preparation method of a composite bone reconstruction scaffold with bone tumor resistance. The preparation method is prepared from raw materials in parts by mass as follows:20-30 parts of polyamide, 20-25 parts of a strontium compound, 15-20 parts of hydroxyapatite, 50-60 parts of calcium phosphate, 5-10 parts of alkaline phosphatase, 50-60 parts of alpha-tricalcium phosphate, 50-60 parts of calcium hydrogen phosphate, 20-30 parts of disodium hydrogen phosphate, 20-30 parts of calcium sulfate powder, 5-10 parts of hydrochloride, 10-20 parts of a calcium hydrogen carbonate suspension, 10-20 parts of phosphoric acid and 10-20 parts of a collagen solution. The composite bone reconstruction scaffold has good integration and can fix injured bone after being contactedwith human bone to prevent secondary injury on one hand and supplement calcium ions to the injured bone to promote growth and recovery of the bone on the other hand.

Description

technical field [0001] The invention relates to the technical field of composite bone reconstruction scaffolds, in particular to a preparation method of an anti-bone tumor composite bone reconstruction scaffold. Background technique [0002] Bone tumor treatment is a comprehensive treatment that combines surgery, chemotherapy and radiotherapy. Due to the limb-salvage treatment of malignant bone tumors in the limbs, the adjacent structures of malignant bone tumors in the spine are complicated, and it is difficult to completely remove the lesion. Preventing recurrence after surgery has become more and more important. However, this problem and the lack of a large amount of bone graft materials required for bone reconstruction after tumor resection are still difficult problems for surgeons. They are the bottleneck affecting the treatment effect of bone tumors and the development of treatment concepts. The traditional treatment for osteoma is to use large resection to remove the ...

AI Technical Summary

Problems solved by technology

The traditional treatment for osteoma is to use large resection to remove the normal tissue around the tumor. For the residual bone defect, it can be repaired by autogenous bone inactivation and replantation, large bone graft fusion joint, artificial joint replacement, etc., but it is not effective. Supplementing calcium ions to autologous bone needs to supplement calcium ions orally from the outside world, which makes recovery slower