Biological porous bone cement prepared by compositing Sr-doped calcium-phosphorus bioglass and alpha-tricalcium phosphate and preparation method thereof

A technology of bioglass and tricalcium phosphate, which is applied in the field of biomedical material preparation, can solve the problems of low compressive strength of bone cement, difficulty in forming porous structure, unfavorable vascular ingrowth and body fluid circulation, etc., so as to facilitate body fluid circulation and dissolve quickly The effect of speed and good application prospects
CN102249728BInactive Publication Date: 2012-11-21TIANJIN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
TIANJIN UNIV
Publication Date
2012-11-21
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a biological porous bone cement prepared by compositing Sr-doped calcium-phosphorus bioglass and alpha-tricalcium phosphate and a preparation method thereof. The bone cement provided by the invention is characterized in that the porousness of the bone cement is 39-57%, and the size of a micropore is between 0.5 um and 4 um; and the compression strength is 23.6-38.5 Mpa. In the invention, through compositing the Sr-doped calcium-phosphorus bioglass and alpha-tricalcium phosphate, the porous-structured bone cement is formed. In the invention, the solidification time andmicrostructure of the bone cement can be adjusted through the rapid dissolving of the Sr-doped calcium-phosphorus glass so as to form a porous structure with a high porousness, and the degradation property of a hydrated product (hydroxyapatite) can be improved; and in addition, by virtue of Sr ions introduced by biodegradable calcium-phosphorus glass, the compression strength of the bone cement is improved, thereby achieving the properties such as high strength and good degradability of the bone cement better.
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Description

technical field

[0001] The invention relates to a Sr-doped calcium phosphorus bioglass composite α-tricalcium phosphate bioporous bone cement and a preparation method, and belongs to the technical field of biomedical material preparation. Background technique

[0002] Calcium Phosphate Cement (CPC) is a new type of artificial bone material that can be used for bone tissue repair. Due to its excellent biocompatibility and in-situ curing in the form of slurry, it can be directly injected into the bone defect site for in situ curing, which solves the problem of difficult shape adaptability of other inorganic biomaterials, so it is widely used in orthopedics, dentistry and plastic surgery. widely used. At the same time, CPC can also be used as an excellent slow-release carrier for antibiotics, anti-tumor drugs and various growth factors. Among them, curing time and product structure are two important factors to measure whether bone cement can meet clinical requirements. In or...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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