Lycopene compound preparation for assisting in treating prostatic cancer and application thereof

A technology of lycopene and prostate cancer, applied in the field of medicine, can solve the problem of regulating the tumor microenvironment of prostate cancer that has not yet been reported, and achieve the effects of assisting in inhibiting prostate cancer, inhibiting growth, and inhibiting proliferation

Active Publication Date: 2018-08-28
新疆金骏阳光生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] It has been reported in the literature that lycopene can inhibit the proliferation of prostate PC-3 cells, but there is no report on the regulation of the tumor microenvironment of prostate cancer, and whether the inhibitory effect of lycopene alone is optimal remains to be confirmed

Method used

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  • Lycopene compound preparation for assisting in treating prostatic cancer and application thereof
  • Lycopene compound preparation for assisting in treating prostatic cancer and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0043] The present embodiment provides a lycopene compound preparation (tablet) for adjuvant treatment of prostate cancer, its components include: lycopene powder 20g, phytosterol 10g, sodium selenite 5g, zinc gluconate 5g, micro Crystalline cellulose 100g, sodium starch glycolate 2g. The preparation method of the tablet of the present invention: after mixing the above-mentioned components evenly, then use 95% ethanol to wet granulate, pass through a 14-mesh sieve, air-dry at 40°C, granulate, add lubricant, sodium starch glycolate, and adjust the tablet weight. 0.5 g was compressed into tablets to obtain tablets.

Embodiment 2

[0045] This embodiment provides a lycopene compound preparation (tablet) with auxiliary treatment for prostate cancer, its components include: lycopene powder 15g, stigmasterol ester 8g, selenium-enriched yeast 4g, zinc oxide 3g, mannitol 80g, dry starch 5g and povidone 5g.

Embodiment 3

[0047] This embodiment provides a lycopene compound preparation (tablet) for adjuvant treatment of prostate cancer. Its components include: 20 g of natural lycopene, 10 g of stigmasterol, 5 g of sodium selenite, 5 g of zinc gluconate, and Use 60g of calcium carbonate, 4g of cross-linked PVP and 5g of maltitol.

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Abstract

The invention relates to technical field of medicines, and provides a lycopene compound preparation for assisting in treating prostatic cancer and application thereof. The preparation is prepared fromthe following components in parts by weight: 1 to 20 parts of lycopene, 1 to 20 parts of phytosterol or phytosterol ester, 0.1 to 10 parts of selenium-containing compound and 0.1 to 10 parts of zinc-containing compound. The lycopene compound preparation has the effect of restraining tumor cells, can restrain the growth of prostate fibroblasts, restrain the propagation of tumor and vascular endothelial cells and regulate prostate immune cells, and has a propagating effect on intraprostatic immune cell T subgroups. The preparation can regulate the tumor microenvironment, and has the effect of assisting in treating prostate cancer.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a lycopene compound preparation for adjuvant treatment of prostate cancer and its application. Background technique [0002] The incidence of prostate cancer is the first among male malignant tumors in European and American countries, and the mortality rate is second only to lung cancer. The incidence of prostate cancer in my country is significantly lower than that in European and American countries, but it has gradually increased in recent years, and there is a trend of younger age of onset and earlier detection. At present, the methods of tumor treatment mainly include surgical treatment, chemical drug therapy and radiotherapy, among which chemical drug therapy and radiotherapy are commonly used treatment methods, but the side effects are serious. With the in-depth treatment of prostate cancer, the important biological characteristics of plant extracts have been widely conce...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61K33/04A61K31/575A61K31/01A61P35/00
CPCA61K31/01A61K31/575A61K33/04A61K33/30A61P35/00A61K2300/00
Inventor 游佩进冯崴肖建民
Owner 新疆金骏阳光生物科技有限公司
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