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Chinese herbal compound for treating idiopathic pulmonary fibrosis as well as preparation method and application thereof

A technology for pulmonary fibrosis and idiopathic pulmonary fibrosis, which is applied to the traditional Chinese medicine compound "Maiwei Yangfei Decoction" for the treatment of idiopathic pulmonary fibrosis and its preparation field, which can solve the problem of whether it is not possible to verify whether idiopathic pulmonary fibrosis is effective or not. Short follow-up time, few observation indicators, etc., to achieve good application prospects, good safety, and the effect of improving clinical symptoms

Active Publication Date: 2018-08-28
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the short observation and follow-up time, few observation indicators and low reliability, it is not yet possible to confirm whether traditional Chinese medicine is effective in treating idiopathic pulmonary fibrosis.

Method used

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  • Chinese herbal compound for treating idiopathic pulmonary fibrosis as well as preparation method and application thereof
  • Chinese herbal compound for treating idiopathic pulmonary fibrosis as well as preparation method and application thereof
  • Chinese herbal compound for treating idiopathic pulmonary fibrosis as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The Chinese medicine compound "Maiwei Yangfei Decoction" in this example is composed of the following Chinese medicine ingredients: Schisandra 10g, Codonopsis 15g, Ophiopogon japonicus 10g, perilla seed 10g, roasted ephedra 6g, aster 15g, tangerine peel 10g, ginger pinellia 10g, asarum 3g , Sunburn Scutellaria 6g, Angelica 10g, Zhigancao 3g.

[0017] The preparation method of the traditional Chinese medicine prescription is as follows: the above-mentioned medicinal materials are mixed, soaked in 10 times of water for more than 3 hours, boiled for 30-40 minutes, and poured out the medicinal liquid. Add 8 times more water and boil for 30-35 minutes, pour out the medicinal solution; add 5 times more water and boil for 30-35 minutes, pour out the medicinal solution. Combine the medicinal liquids for three times, simmer or concentrate the medicinal liquids to about 400mL with a reduced-pressure rotary evaporator to obtain a decoction for clinical use. 1 dose per day, 200 mL...

Embodiment 2

[0019] The traditional Chinese medicine compound "Maiwei Yangfei Decoction" in this example is composed of the following traditional Chinese medicine ingredients: Schisandra 5g, Codonopsis 45g, Ophiopogon japonicus 5g, Perilla 30g, Ephedra 3g, Ziyuan 45g, Tangerine peel 30g, Pinellia ginger 5g, Asarum 10g , Sunburn Scutellaria 3g, Angelica 30g, Zhigancao 1g.

[0020] The preparation method of Chinese medicine prescription is identical with embodiment 1.

Embodiment 3

[0022] The traditional Chinese medicine compound "Maiwei Yangfei Decoction" in this example is composed of the following traditional Chinese medicine ingredients: Schisandra 30g, Codonopsis 10g, Ophiopogon japonicus 30g, Perilla 5g, Sun-roasted Ephedra 18g, Aster 10g, Tangerine Peel 5g, Jiang Pinellia 30g, Asarum 1g , Sunburn Scutellaria 18g, Angelica 5g, Zhigancao 10g.

[0023] The preparation method of Chinese medicine prescription is identical with embodiment 1.

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Abstract

The invention discloses a Chinese herbal compound for treating idiopathic pulmonary fibrosis as well as a preparation method and application thereof. The Chinese herbal compound is 'wheat flavor lungnourishing soup', which is prepared from twelve traditional Chinese medicine raw materials such as schisandra chinensis, codonopsis pilosula, radix ophiopogonis, fructus perillae, roasted ephedra herb, aster, pericarpium citri reticulatae, ginger processed pinellia, asarum, roasted radix scutellariae, angelica sinensis and roasted licorice roots. A clinical experiment shows that clinical symptomsof an idiopathic pulmonary fibrosis patient, particularly a patient suffering from deficiency of both vital energy and yin, can be obviously improved, the living quality is improved, and the exercisetolerance is enhanced; the Chinese herbal compound is high in safety, and can reduce the lowering rate of the lung functions to a certain extent.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and more specifically relates to a traditional Chinese medicine compound "Maiwei Yangfei Decoction" for treating idiopathic pulmonary fibrosis, its preparation method and application. Background technique [0002] Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial lung disease with lesions confined to the lungs, mostly in middle-aged and elderly people, and its lung histology and / or chest High-resolution CT characteristically presents as usual interstitial pneumonia. The main clinical manifestations are progressively aggravated dyspnea, accompanied by restrictive ventilatory dysfunction and gas exchange disorder, leading to hypoxemia and even respiratory failure. In European and North American countries, the incidence of idiopathic pulmonary fibrosis is about 2.8-9.3 / 100,000 people. Its prognosis is poor and its mortality rate is high. The ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P11/00
CPCA61K36/17A61K36/232A61K36/268A61K36/28A61K36/344A61K36/484A61K36/535A61K36/539A61K36/57A61K36/752A61K36/79A61K36/8888A61K36/8968A61K2236/331A61K2236/39A61K2236/51A61P11/00A61K2300/00
Inventor 周贤梅曹爱玲何海浪魏瑜孙子凯陈四清
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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