A kind of preparation method of high antibacterial performance medical adhesive

Abstract

The present invention relates to a preparation method of a medical adhesive with high antibacterial performance, which is characterized in that it comprises the following steps: step 1, adding sodium alginate, lignin, tannic acid, and a stabilizer Bacterial water, heated to 100°C, stirred and dissolved for 150min, cooled to room temperature to obtain aqueous solution A; step 2, poly(α-isobutyl cyanoacrylate-α-octyl cyanoacrylate), polyurethane, polyisoprene According to the ratio of parts, add alkenes to seabuckthorn seed oil, heat to 80°C and stir for 75min, cool to room temperature to obtain seabuckthorn seed oil solution B; step 3, mix the above aqueous solution A and seabuckthorn seed oil solution B evenly, and Add high-efficiency antibacterial components and formaldehyde inhibitors, and stir for 4 hours; Step 4, filter and sterilize the product obtained in Step 3, subpackage, seal, and package to obtain a medical adhesive with high antibacterial performance.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a medical adhesive with high antibacterial performance and a preparation method thereof. Background technique [0002] With the advancement of medicine, the clinical requirements for the effect of surgical techniques and auxiliary materials are getting higher and higher. The philosophy of modern medicine is to minimize the suffering of patients and to allow patients to recover as quickly as possible. Medical adhesives are a branch of medical polymers. They use biological tissues as bonding objects. Most of the tissues and organs of the human body Adhesive technology can be used to replace partial sutures and ligation operations during the treatment process without anesthesia; it will automatically fall off after the wound is healed. Compared with traditional methods, the use of medical adhesives can effectively shorten the operation time and reduce the pati...

AI Technical Summary

Problems solved by technology

[0003] At present, the main research direction of medical adhesives is to improve the bonding strength of various adhesives. However, the biomedical materials currently used in surgical operations do not have the function of bacterial immunity, and are prone to bacterial adhesion and reproduction, becoming a source of infection in surrounding tissues. , bringing huge mental and economic pressure to patients, endowing medical materials with antibacterial activity is the only effective way to solve this problem

The production of formaldehyde during the storage and use of cyanoacrylate medical adhesives has side effects on biological tissues, and with the increase of formaldehyde concentration, the damage to organisms increases, which seriously affects the effect and application of medical adhesives