6 results about "Octyl cyanoacrylate" patented technology

The application relates to the technical field of medical materials, and particularly discloses a kind of bionic medical tissue adhesive and a preparation method thereof.A kind of bionic medical tissue adhesive is made of raw materials containing the following weight parts: alpha-cyano octyl acrylate 30-35 parts;degradable polymer material 20-30 parts;gelatin 1-5 parts;polyethylene glycol 2-5 parts;sterile water 20-30 parts;sodium alginate 2-4 parts;antibacterial agent 8-10 parts;stabilizing protective agent 1-3 parts;mussel extract 1-3 parts;slug extract 1-3 parts;its preparation method is: polyethylene glycol, sterile water, sodium alginate, antibacterial agent, stabilizing protective agent, mussel extract and slug extract are mixed, and stirred uniformly;then alpha-cyano octyl acrylate, degradable polymer material and gelatin are added, heated to 40-60 DEG C and stirred for 20-40 min, and the bionic medical tissue adhesive can be obtained.The bionic medical tissue adhesive of the application can better handle the skin tissue changes occurring in the proliferation period, so that the prominence of the scar formed in the later period is smaller, the whole is relatively flat and smooth, and thus the scar is greatly improved.

The present invention provides a cyanoacrylate composition that improves high-temperature strength performance while maintaining a desirable level of heat resistance. [Solution] A cyanoacrylate composition is provided, comprising (a) a cyanoacrylate component comprising a combination of (i) allyl cyanoacrylate and (ii) another cyanoacrylate selected from the group consisting of methyl cyanoacrylate, ethyl-2-cyanoacrylate, propyl cyanoacrylate, butyl cyanoacrylate, octyl cyanoacrylate and β-methoxyethyl cyanoacrylate, (b) fluorobenzonitrile, (c) hydrogenated aromatic anhydride, and (d) a reinforcing component.

The invention relates to the field of biomedical materials, in particular to cyanoacrylate medical blood vessel blocking glue and a preparation method thereof.The cyanoacrylate medical blood vessel blocking glue is prepared from, by mass, 30-35 parts of 2-octyl cyanoacrylate, 7-8 parts of lactide modified hydroxyethyl methylacrylate, 0.02-0.03 part of polymerization inhibitor propyl gallate, 0.02-0.03 part of initiator, 0.02-0.03 part of initiator, 0.02-0.03 part of initiator, 0.02-0.03 part of initiator and the balance water. By innovatively adopting various functional components and carrying out synergistic compatibility and precise preparation, compared with the prior art, the comprehensive performance of the product is remarkably improved, and the plugging agent has the advantages of rapid and reliable plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect, good plugging effect and the like. Meanwhile, good biocompatibility, intraoperative developing capacity and a potential drug sustained release function are achieved, operation is easy and convenient, performance is stable, a safer and more efficient choice is provided for clinical vascular interventional therapy, and wide application prospects are achieved in the fields of cardiovascular and neurological intervention, peripheral vascular embolism and the like.

This invention relates to a photocurable composition comprising: cyanoacrylate A selected from the group consisting of n-hexyl cyanoacrylate, n-heptyl cyanoacrylate, n-octyl cyanoacrylate, and mixtures thereof; a free radical photoinitiator; a metallocene compound; compound B selected from the group consisting of boron trifluoride, boron trifluoride diethyl ether, boron trifluoride dihydrate, boron trifluoride ethanol, boron trifluoride methanol, boron trifluoride acetic acid, boron trifluoride butyl ether, boron trifluoride butanol, boron trifluoride propanol, boron trifluoride dimethyl sulfide, boron trifluoride acetonitrile, boron trifluoride tetrahydrofuran, and boron trifluoride isopropanol; and optionally a free radical polymerization inhibitor, provided that when the photocurable composition contains a free radical polymerization inhibitor, its weight content is 0.04 wt.% or less; wherein the molar content of compound B is greater than or equal to 0.141 mmol per 1 kg of composition; and wherein the molar ratio of metallocene compound / compound B ranges from 2 to 8.

The present invention discloses an inducer for mouse liver S9 and an inducing method thereof. The inducer comprises octyl cyanoacrylate and etaconazole; and through optimization experiments, the optimal inducer dosage and induction time are obtained, and an effective method for inducing liver S9 is obtained; the experimental results show that the inducing method for mouse liver S9 according to the present invention has a strong inducing effect on the expression of typical metabolic enzymes of chemical substances, especially on metabolic enzymes 2E, 2C, and 4A which have no inducing effect in the traditional inducing method. Moreover, the inducing agent method of the present invention is economical and easily available, and is applicable to the safety evaluation of industrial chemicals, drugs, and environmental chemicals.

The invention provides medical glue for treating aneurysm and a preparation method of the medical glue, and the medical glue comprises the following components in parts by weight: 55-61 parts of n-octyl cyanoacrylate; 4 parts of a polymerization inhibitor; 3.3-5 parts of a first stabilizer; 5-8 parts of a second stabilizer; 15-22 parts of a plasticizer; 2.6 to 4.8 parts of a first thickening agent; 0.2 to 0.3 part of a second thickening agent; 4-5 parts of a bonding strength modifier; the first thickening agent is one or two of polyisobutyl methacrylate or cellulose acetate butyrate, and the second thickening agent is calixarene. The medical glue provided by the invention has the characteristics of high viscosity, high curing speed, good flexibility and long degradation period, and is suitable for blocking aneurysm.