55results about How to "Guaranteed sustained release effect" patented technology

The invention discloses a sustained-release gel-breaking type fracturing propping agent for fracturing an oilfield. The propping agent sequentially comprises a base material, a medicament carrying layer and a sustained release layer from inside to outside, wherein the medicament carrying layer comprises a gel breaking agent and a filling agent, and the sustained release layer comprises a film forming material and a pore forming agent. The invention further provides a preparation method of the sustained-release gel-breaking type fracturing propping agent. In an actual application, the sustained-release gel-breaking type fracturing propping agent disclosed by the invention can enter the stratum along with fracturing fluid, and the gel breaking agent can be released slowly under the stratum conditions; and as the propping dosage is great, the gel breaking agent is distributed uniformly, and gel breaking can be realized to the greatest extent. Simultaneously, a chemical material coating the gel breaking agent can be stilly firmly coated on matrix particles, thus the problems of breaking, reflux and stratum embedding of the propping agent can be reduced.

A preparing method of a selenium rich slow-release particle matrix fertilizer is disclosed. Waste glass and selenium rich ore are adhered into a whole part so that fertilizer effects are rich, a slow release effect is good, and disadvantages of fertilizers at present, namely single fertilizer effects, easy soil agglomeration and complex compositions, are overcome. The selenium rich slow-release particle matrix fertilizer prepared by the method is good in fertilizer effects, low in raw material cost, rich in sources, simple in preparing process, free of pollution to the environment and beneficial to industrial production.

The invention belongs to the technical field of medicine preparation, and discloses a preparation method of a ziconotide injection hypodermic implant as well as the ziconotide injection hypodermic implant prepared by the method. The implant prepared by the method is dissolved by sterile water for injection before use and is then injected to human subcutaneous tissues. The implant prepared by the method is a novel sustained-release preparation which can be subcutaneously injected in form of a liquid. Under the effect of body temperature, the liquor becomes a gel which is slowly released in vivo, so that a long-acting effect of treating and relieving pains is realized.

The present invention relates to a preparation method of a medical adhesive with high antibacterial performance, which is characterized in that it comprises the following steps: step 1, adding sodium alginate, lignin, tannic acid, and a stabilizer Bacterial water, heated to 100°C, stirred and dissolved for 150min, cooled to room temperature to obtain aqueous solution A; step 2, poly(α-isobutyl cyanoacrylate-α-octyl cyanoacrylate), polyurethane, polyisoprene According to the ratio of parts, add alkenes to seabuckthorn seed oil, heat to 80°C and stir for 75min, cool to room temperature to obtain seabuckthorn seed oil solution B; step 3, mix the above aqueous solution A and seabuckthorn seed oil solution B evenly, and Add high-efficiency antibacterial components and formaldehyde inhibitors, and stir for 4 hours; Step 4, filter and sterilize the product obtained in Step 3, subpackage, seal, and package to obtain a medical adhesive with high antibacterial performance.

The invention provides memantine hydrochloride sustained release micro-pill tablets and a preparation method thereof. The memantine hydrochloride sustained release micro-pill tablets are prepared by directly pressing self-protected multi-layer micro-pills, and a filling agent, a disintegrating agent and other auxiliary tablet materials do not need to be added. The self-protected multi-layer micro-pill is composed of a pill core, a medicine layer, a sustained release layer, a protective layer and a compressible composite auxiliary material layer, can tolerate extrusion of a certain tabletting pressure, and contributes to keeping the integrity of a micro-pill sustained release coating and good sustained release properties of the medicine. The self-protected multi-layer micro-pill also has high compressibility, disintegration and lubricating property and can be directly pressed into tablets, and the prepared memantine hydrochloride sustained release micro-pill tablets have good drug content uniformity.

The invention relates to a selenium-containing coating agent for a sustained release fertilizer special for selenium-rich agricultural products and a preparation method for the selenium-containing coating agent. The selenium-containing coating agent contains the following components: cellulose, polyvinyl alcohol, acrylic resin, epoxy resin, a crosslinking agent, an emulsifying agent, an initiator, selenite and deionized water. The invention also provides a method for preparing the selenium-containing coating agent. Selenium is dispersed in a coating agent, and the selenium is slowly released;and the prepared sustained release fertilizer can meet the requirements of the selenium-rich agricultural products in all growth periods through one-time application, solves that problems that a selenium-enriching agent is required to be sprayed on leaf surfaces for multiple times to cause high labor consumption and human poisoning is caused by improper spraying, and also overcomes a defect that the utilization rate of a selenium-enriching fertilizer through soil application is low. The sustained release fertilizer prepared from the coating agent has effects of improving fertilizer utilization rate, increasing crop yield and reducing environmental pollution.