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78results about How to "Good release performance" patented technology

Integrated utilization technique for multi-metal ore containing gold and silver by chlorine carrier chlorination method

InactiveCN101215633AStrong leaching effectEffective soakingFlotationProcess efficiency improvementSlagChemical separation
The invention discloses a mineral processing and metallurgical technology which comprehensively uses multi-metallic ore through a chloride carrier chlorination process, which comprises calcining crude ore into slag through grinding, flotation and concentrate powder, separating out gold, silver liquid and barren liquor from slag through pitch absorption by penetrating through chloridization leach pregnant solution, preparing gold and silver through chemically separating pregnant solution, depositing and filtering barren liquor to recycle and separate copper, lead and zinc, and reusing filter solution which is sodium chloride passing through the steps of chlorination leaching above. The mineral processing and metallurgical technology of the invention has the characteristics of no toxic and environment-friendly, fast speed, low cost and multiple-kind comprehensive recycling products. The invention has high comprehensive recovering index, the recovery ratio of gold and silver all can be larger than 95%, the recovery ratio copper, lead and zinc and the like which are comprehensively recovered all can be larger than 90%, and the invention can change ferro-sulphur ore into iron-smelting raw material. The invention is superior to traditional, which has significant technology superiority, economic benefits superiority, environmental benefit superiority and high comprehensive utilization degree.
Owner:石嵩高

Acipimox film-controlled slow-release pellet capsule

The invention relates to an acipimox film-controlled slow-release pellet capsule. A slow-release film of the acipimox film-controlled slow-release pellet utilizes Eurdragit NE 30D as a film-formation material. A pellet core of the acipimox film-controlled slow-release pellet contains low-substituted hydroxypropyl cellulose having high expansibility, and also contains pharmaceutically acceptable common excipients for the slow-release pellet, wherein preferably, the excipients comprise microcrystalline cellulose and lactose, and the pellet core comprises 10 to 40wt% of the low-substituted hydroxypropyl cellulose. The slow-release film comprises the Eurdragit NE 30D, triethyl citrate as a plasticizer and talcum powder as an antiplastering aid, wherein preferably, a ratio of Eurdragit NE 30D to triethyl citrate to talcum powder is 30: 2: 4 and coating weight gain is in a range of 20 to 39%. The acipimox film-controlled slow-release pellet comprises the pellet core containing low-substituted hydroxypropyl cellulose having high water expansibility and thus after absorbing water, the acipimox film-controlled slow-release pellet obviously expands so that the slow-release film is stretched; the thickness of the slow-release film is reduced; the water-permeable micropore size is increased; and permeability is improved and permeability reduction caused by film aging is counteracted. Therefore, in middle and later stages, the acipimox film-controlled slow-release pellet release rate is basically constant; in the last stage, residues are less; and stable release performances can be kept prior to expiration date.
Owner:北京天衡药物研究院有限公司

Isosorbide mononitrate sustained-release pellet, and isosorbide mononitrate quick-release and sustained-release pellet capsule adopting it

The invention relates to an isosorbide mononitrate sustained-release pellet, and an isosorbide mononitrate quick-release and sustained-release pellet capsule adopting it. The sustained-release film of the sustained-release pellet adopts Eurdragit RS 30D as a film forming material, the core of the sustained-release pellet contains high-expansibility sodium carboxymethyl starch and a pharmaceutically-acceptable excipient commonly used for sustained-release pellets, and optimally, the excipient is microcrystalline cellulose, wherein the weight percentage of sodium carboxymethyl starch in the core of the sustained-release pellet is 5-20%. The sustained-release film of the sustained-release pellet includes the Eurdragit RS 30D, a plasticizer triethyl citrate and an anti-adherent talcum powder, the optimal ratio of the Eurdragit RS 30D to triethyl citrate to the talcum powder is 30:3:4, and the optimal coating weight gain is 19-38%. The core will obviously expand after absorbing water because of the containment of sodium carboxymethyl starch highly expanding after contacting with water, so the sustained-release film is stretched, the thickness of the film is thinned, the apertures of water-pervious micro-pores are increased, the permeability is good, and the permeability decrease caused by film ageing is compensated, thereby the middle and later stage release speed is basically constant, the last stage residue is small, and a stable release performance is always maintained prior to the expiration date.
Owner:北京天衡药物研究院有限公司

Choline fenofibrate film-controlled enteric slow-release pellet capsule

The invention relates to a choline fenofibrate film-controlled enteric slow-release pellet capsule. A slow-release film of the choline fenofibrate film-controlled enteric slow-release pellet utilizes Eurdragit RS 30D as a film-formation material. A pellet core of the choline fenofibrate film-controlled enteric slow-release pellet contains low-substituted hydroxypropyl cellulose having high expansibility, and also contains a pharmaceutically acceptable common excipient for the slow-release pellet, wherein preferably, the excipient comprises microcrystalline cellulose, and the pellet core comprises 10 to 40wt% of the low-substituted hydroxypropyl cellulose. The slow-release film comprises Eurdragit RS 30D, triethyl citrate as a plasticizer and talcum powder as an antiplastering aid, wherein preferably, a ratio of urdragit RS 30D to triethyl citrate to talcum powder is 30: 3: 4 and a film weight increasing ratio is in a range of 20 to 38%. The choline fenofibrate film-controlled enteric slow-release pellet comprises the pellet core containing low-substituted hydroxypropyl cellulose having high water expansibility and thus after absorbing water, the choline fenofibrate film-controlled enteric slow-release pellet expands so that the slow-release film is stretched; the thickness of the slow-release film is reduced; the water-permeable micropore size is increased; and permeability is improved and the permeability reduction caused by film aging is counteracted. Therefore, in middle and later stages, the choline fenofibrate film-controlled enteric slow-release pellet release rate is basically constant; in the last stage, residues are less; and stable release performances can be kept in the period of validity.
Owner:北京天衡药物研究院有限公司

High-elasticity silicone rubber lettering film and preparation method and application method thereof

The invention relates to the technical field of thermal transfer printing lettering film, and in particular, relates to a high-elasticity silicone rubber lettering film and a preparation method and anapplication method thereof. The high-elasticity silicone rubber lettering film comprises a load-bearing substrate, a release layer, a surface layer silicone rubber ink layer, an anti-photopermeable silicone rubber ink layer, an adhesive interfacial agent layer and a TPU hot melt adhesive film which are connected from bottom to top successively; the adhesive interfacial agent layer is prepared from an adhesive interfacial agent, and the adhesive interfacial agent is an adhesive interfacial agent containing dual-resin components. The silicone rubber lettering film has the advantages of both thesilicone rubber material and the TPU material, has good elasticity, tearing strength, weatherability, yellowing resistance, water washing resistance and other comprehensive properties, has layers noteasy to separate, is not easy to discolor or fade by sunlight exposure, and has the water-washing fading rate not less than 0.5%, is not easy to dye when being mixed and washed with materials with other colors, and is high in stability, easy to bond with a variety of materials, high in bonding strength, not easy to peel off, good in stability, delicate in hand feeling, good in aesthetic degree, and long in service life.
Owner:卢汉军

Venlafaxine hydrochloride film-controlled slow-release pellet capsule

The invention relates to a venlafaxine hydrochloride film-controlled slow-release pellet capsule. A slow-release film of the venlafaxine hydrochloride film-controlled slow-release pellet utilizes Kollicoat SR30D as a film-formation material. A pellet core of the venlafaxine hydrochloride film-controlled slow-release pellet contains low-substituted hydroxyprepyl cellulose having high expansibility, and also contains a pharmaceutically-acceptable common excipient for the slow-release pellet, wherein preferably, the excipient comprises microcrystalline cellulose, and the pellet core comprises 10 to 40wt% of low-substituted hydroxyprepyl cellulose. The slow-release film comprises Kollicoat SR30D, triethyl citrate as a plasticizer and talcum powder as an antiplastering aid, wherein preferably, a ratio of Kollicoat SR30D to triethyl citrate to talcum powder is 30: 1: 4 and a film weight increasing ratio is in a range of 21 to 39%. The venlafaxine hydrochloride film-controlled slow-release pellet comprises the pellet core containing low-substituted hydroxyprepyl cellulose having high water expansibility and thus after absorbing water, the venlafaxine hydrochloride film-controlled slow-release pellet obviously expands so that the slow-release film is stretched; the thickness of the slow-release film is reduced; the water-permeable micropore size is increased; and permeability is improved and the permeability reduction caused by film aging is counteracted. Therefore, in middle and later stages, the venlafaxine hydrochloride film-controlled slow-release pellet release rate is basically constant; in the last stage, residues are less; and stable release performances can be kept in the period of validity.
Owner:北京天衡药物研究院有限公司

Glipizide film-controlled slow-release pellet capsule

The invention relates to a glipizide film-controlled slow-release pellet capsule. A slow-release film of the glipizide film-controlled slow-release pellet utilizes Eurdragit RL 30D as a film-formation material. A pellet core of the glipizide film-controlled slow-release pellet contains sodium carboxymethyl starch having high expansibility, and also contains pharmaceutically-acceptable common excipients for the slow-release pellet, wherein preferably, the excipients comprise microcrystalline cellulose, lactose and sodium dodecyl sulfate, and the pellet core comprises 5 to 20wt% of sodium carboxymethyl starch. The slow-release film comprises Eurdragit RL 30D, triethyl citrate as a plasticizer and talcum powder as an antiplastering aid, wherein preferably, a ratio of Eurdragit RL 30D to triethyl citrate to talcum powder is 30: 3: 4 and a film weight increasing ratio is in a range of 17 to 36%. The glipizide film-controlled slow-release pellet comprises the pellet core containing sodium carboxymethyl starch having high water expansibility and thus after absorbing water, the glipizide film-controlled slow-release pellet obviously expands so that the slow-release film is stretched; the thickness of the slow-release film is reduced; the water-permeable micropore size is increased; and permeability is improved and the permeability reduction caused by film aging is counteracted. Therefore, in middle and later stages, the glipizide film-controlled slow-release pellet release rate is basically constant; in the last stage, residues are less; and stable release performances can be kept in the period of validity.
Owner:内蒙古天衡医院管理有限公司

Ambroxol hydrochloride film-controlled slow-release pellet capsule

The invention relates to an ambroxol hydrochloride film-controlled slow-release pellet capsule. A slow-release film of the ambroxol hydrochloride film-controlled slow-release pellet utilizes Kollicoat SR 30D as a film-formation material. A pellet core of the ambroxol hydrochloride film-controlled slow-release pellet contains low-substituted hydroxyprepyl cellulose having high expansibility, and also contains pharmaceutically-acceptable common excipients for the slow-release pellet, wherein preferably, the excipients comprise microcrystalline cellulose and lactose, and the pellet core comprises 10 to 40wt% of low-substituted hydroxyprepyl cellulose. The slow-release film comprises Kollicoat SR 30D, triethyl citrate as a plasticizer, and talcum powder as an antiplastering aid, wherein preferably, a ratio of Kollicoat SR 30D to triethyl citrate to talcum powder is 30: 1.5: 4 and a film weight increasing ratio is in a range of 20 to 36%. The ambroxol hydrochloride film-controlled slow-release pellet comprises the pellet core containing low-substituted hydroxyprepyl cellulose having high water expansibility and thus after absorbing water, the ambroxol hydrochloride film-controlled slow-release pellet obviously expands so that the slow-release film is stretched; the thickness of the slow-release film is reduced; the water-permeable micropore size is increased; and permeability is improved and the permeability reduction caused by film aging is counteracted. Therefore, in middle and later stages, the ambroxol hydrochloride film-controlled slow-release pellet release rate is basically constant; in the last stage, residues are less; and stable release performances can be kept in the period of validity.
Owner:北京天衡药物研究院有限公司

Liraglutide multivesicular liposome and preparation method and application thereof

The invention relates to the field of medicines, and particularly relates to a liraglutide multivesicular liposome and a preparation method and an application thereof. The liraglutide multivesicular liposome provided by the invention comprises liraglutide, a membrane material, an osmotic pressure regulator and a stabilizer. The liraglutide multivesicular liposome prepared by the invention has goodstability, high drug encapsulation rate, large drug loading capacity, slow and steady drug release rate and no burst release phenomenon, significantly improves the bioavailability of the drug, thereby improving the curative effect, reduces dose-related side effects of the drug and medication cost and has a higher application value. Experiments shows that the liposome provided by the present invention can continuously release the drug in vitro for about 432 hours, and provide a stable blood concentration in vivo, significantly prolongs in-vivo retention time compared to other injections, showsobvious pharmacokinetic characteristics of a sustained release preparation, can provide a normal steady blood glucose level, plays hypoglycemic effect for 312 hours, and has the relative bioavailability of 661% to injections.
Owner:SHENYANG PHARMA UNIVERSITY

Mold release agent and preparation method thereof

The invention relates to the technical field of ironmaking agents, in particular to a mold release agent. The mold release agent is prepared by mixing and stirring a dry material and water, the dry material comprises, by weight, 0.5-1.5% of carboxymethylcellulose, 10.0-15% of sodium bentonite, 50-60% of low carbon coal slurry, 15-20% of aluminum-magnesium refractory mortar, 10-15% of coal powder and the balance water, wherein the weight of the water is 9-11 times of the total weight of the dry material. The preparation method comprises the steps that when being poured, the mold release agent forms a sintered layer of 1-2 mm under the high temperature of molten iron, an isolation layer can be effectively formed between the molten iron and a cast iron mold, a cast iron block can smoothly fall off from the cast iron mold, the mold release performance of the mold release agent is good, the mold release rate is up to 100%, the cast iron mold can be protected and is not easily deformed, theservice life of the cast iron mold can be remarkably prolonged, the low carbon coal slurry is generally thrown away as waste, the low carbon coal slurry is used as the main component of the mold release agent, and waste using is achieved, so that the cost of the release agent is low, and popularization is facilitated.
Owner:PANGANG GROUP TITANIUM INDAL

Cefaclor film-controlled slow-release pellet capsule

The invention relates to a cefaclor film-controlled slow-release pellet capsule. A slow-release film of the cefaclor film-controlled slow-release pellet utilizes a mixture of aqueous dispersion Eurdragit RL 30D and Eurdragit RS 30D as a film-formation material, wherein a weight ratio of Eurdragit RL 30D to Eurdragit RS 30D in the mixture is 4: 1. A pellet core of the cefaclor film-controlled slow-release pellet contains sodium carboxymethyl starch having high expansibility, and also contains pharmaceutically-acceptable common excipients for the slow-release pellet, wherein preferably, the excipients comprise microcrystalline cellulose and lactose, and the pellet core comprises 5 to 20wt% of the sodium carboxymethyl starch. The slow-release film comprises the mixture of Eurdragit RL 30D and Eurdragit RS 30D, triethyl citrate as a plasticizer, and talcum powder as an antiplastering aid, wherein preferably, a ratio of Eurdragit RL 30D to Eurdragit RS 30D to triethyl citrate to talcum powder is 24: 6: 2: 4 and a film weight increasing ratio is in a range of 23 to 40%. The cefaclor film-controlled slow-release pellet comprises the pellet core containing sodium carboxymethyl starch having high water expansibility and thus after absorbing water, the cefaclor film-controlled slow-release pellet obviously expands so that the slow-release film is stretched; the thickness of the slow-release film is reduced; the water-permeable micropore size is increased; and permeability is improved and the permeability reduction caused by film aging is counteracted. Therefore, in middle and later stages, the cefaclor film-controlled slow-release pellet release rate is basically constant; in the last stage, residues are less; and stable release performances can be kept in the period of validity.
Owner:北京天衡药物研究院有限公司

Metoprolol fumarate film-controlled slow-release pellet capsule

The invention relates to a metoprolol fumarate film-controlled slow-release pellet capsule. A slow-release film of the metoprolol fumarate film-controlled slow-release pellet utilizes Eurdragit RS 30D as a film-formation material. A pellet core of the metoprolol fumarate film-controlled slow-release pellet contains croscarmellose sodium having high expansibility, and also contains a pharmaceutically-acceptable common excipient for the slow-release pellet, wherein preferably, the excipient comprises microcrystalline cellulose, and the pellet core comprises 5 to 20wt% of croscarmellose sodium. The slow-release film comprises Eurdragit RS 30D, triethyl citrate as a plasticizer, and talcum powder as an antiplastering aid, wherein preferably, a ratio of Eurdragit RS 30D to triethyl citrate to talcum powder is 30: 3: 4 and a film weight increasing ratio is in a range of 18 to 33%. The metoprolol fumarate film-controlled slow-release pellet comprises the pellet core containing croscarmellose sodium having high water expansibility and thus after absorbing water, the metoprolol fumarate film-controlled slow-release pellet obviously expands so that the slow-release film is stretched; the thickness of the slow-release film is reduced; the water-permeable micropore size is increased; and permeability is improved and the permeability reduction caused by film aging is counteracted. Therefore, in middle and later stages, the metoprolol fumarate film-controlled slow-release pellet release rate is basically constant; in the last stage, residues are less; and stable release performances can be kept in the period of validity.
Owner:北京天衡药物研究院有限公司

Losartan potassium membrane controlled-release pellet capsule

The invention relates to a losartan potassium membrane controlled-release pellet capsule. The controlled-release film of the pellet adopts Eurdragit NE 30D as a film forming material, the core of the controlled-release pellet contains high-expansibility low-substituted hydroxypropylcellulose and a pharmaceutically-acceptable excipient commonly used for controlled-release pellets, and optimally, the excipient is microcrystalline cellulose, wherein the weight percentage of the low-substituted hydroxypropylcellulose in the core of the controlled-release pellet is 10-40%. The controlled-release film of the controlled-release pellet includes the Eurdragit NE 30D and an anti-adherent talcum powder, the optimal ratio of the Eurdragit NE 30D to the talcum powder is 30:6, and the optimal coating weight gain is 19-36%. The core will obviously expand after absorbing water because of the containment of the low-substituted hydroxypropylcellulose highly expanding after contacting with water, so the controlled-release film is stretched, the thickness of the film is thinned, the apertures of water-pervious micro-pores are increased, the permeability is good, and the permeability decrease caused by film ageing is compensated, thereby the middle and later stage release speed is basically constant, the last stage residue is small, and a stable release performance is always maintained prior to the expiration date.
Owner:内蒙古天衡医院管理有限公司

Preparation method of primary-taste modified rice fresh keeping agent material

InactiveCN109007017AMitigation release efficiencyGood slow releaseEdible seed preservationFood additiveHusk
The invention relates to a preparation method of a primary-taste modified rice fresh keeping agent material, and belongs to the technical field of food additive materials. The technical scheme adoptedby the invention lies in that the primary-taste modified rice fresh keeping agent material is prepared by using rice husks as raw materials; the rice husks contain rich antioxidation peptide, the rice husks are subjected to enzymolysis and collection, the rice husks are coated with essential oil, and a microcapsule structure is formed; the microcapsule structure can effectively relieve the releasing efficiency of the essential oil, so that the essential oil material has excellent slow release performance; in the storage course, due to massive release of the essential oil at the initial stage,after the essential oil disappears at the later stage, due to the effects of the antioxidation peptide, the fresh keeping agent material continues forming antioxygenic properties, so that the antioxidation durability of the rice fresh keeping agent material can be effectively improved; an adsorbent material is prepared by using the rice husks as raw materials, so that when the adsorbent materialis added to fresh keeping agent microspheres, the adsorbent material can effectively adsorb surplus essential oil smell; and besides, excellent pore canal structure of the fresh keeping agent materialcan be maintained, and the releasing properties and the durability of the fresh keeping agent material can be stable.
Owner:FOSHAN WANYANG BIOLOGICAL TECH CO LTD
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