Precise control method for typhoid and paratyphoid intestinal infectious disease epidemic situation

Abstract

The invention discloses a precise control method for a typhoid and paratyphoid intestinal infectious disease epidemic situation in the technical field of infectious disease control. Through the comprehensively utilization of the theories of five etiology subjects of epidemiology, environmental hygiene, microbiology, molecular biology, and lemology, the etiology differentiation and fusion two-way result conclusion of the propagation circulation or pathogen flow is obtained, investigation and analysis improve the etiologic research accuracy, the pathogen type and source are clear, and the basisis provided for pollution source determination, transmission links and cross-region diffusion; through the dividing of the spreading risk cases and carriers and the public health management, the infection sources is divided into highly-spread risk cases and carriers and general cases and carriers, the highly-spread risk cases and carriers and general cases and carriers are subjected to the publichealth management including hierarchical isolation treatment, hospital treatment, excrement detection and carrying state clearing program, therefore, the method is more scientific and targeted.

Description

technical field [0001] The invention relates to the technical field of infectious disease control, and specifically relates to a precise control method for typhoid and paratyphoid intestinal infectious diseases. Background technique [0002] Typhoid fever and paratyphoid fever are acute intestinal infectious diseases caused by Salmonella enterica subspecies typhoid serotype, Salmonella enterica subspecies paratyphoid A or B or C serotype infection. It is a serious public health problem in underdeveloped countries and developing countries. The annual estimated number of cases and deaths are 16 million and 600,000 respectively, among which the cases in Asia and Africa account for 62% and 35% respectively The main route of transmission is through water pollution, food contamination and close contact. The onset is affected by social factors such as local economic development level, sanitation facilities, living conditions, hygiene habits, etc. Risk factors in endemic areas inclu...

AI Technical Summary

Problems solved by technology

[0004] The existing control methods for intestinal infectious diseases have the following deficiencies: 1. Usually, only two etiology disciplines of epidemiology and etiology are used for etiology research, and the information of environmental hygiene investigation, microbiology, and molecular biology research is lacking or insufficient , not to mention the investigation and analysis of pathogen genomics; 2. The "infection source-transmission route-susceptible population" that clarifies the causal relationship between the cause and the disease focuses on the accuracy of the three links, and does not pay attention to the transmission chain and transmission cycle Flowing with pathogens is the main mode of dissemination; 3. In terms of the risk of transmission between cases and carriers and their public health management, there is no hierarchical isolation and treatment of cases and carriers, hospitalization, stool testing, and clearance of carrier status; 4 , In terms of data-based early warning of infectious disease epidemics, there is a lack of information on the differentiation and integration of the five disciplines of epidemiology, environmental hygiene, microbiology, molecular biology, and infectious disease, as well as individuality and commonality, or insufficient information, making it difficult to complete Systematic, procedural, and staged data-based early warning; 5. In terms of time and space nodes of infectious disease epidemic changes, the corresponding time and space nodes, staged health emergencies, etc. are not clear, and comprehensive prevention and control is the main method; 6. Precise control of infectious disease epidemics On the one hand, comprehensive control is adopted, there are limitations in etiology research, case management, data-based early warning, and space-time control, and the quality, effect, and benefit of control are not sufficient. The precise control method of the epidemic situation to deal with and effectively control the epidemic situation of typhoid and paratyphoid enteric infectious diseases

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