64 results about "Paratyphoid fever" patented technology

The invention discloses a traditional Chinese drug composition for pig and a preparation method and application thereof. The composition comprises drug substances of 6-18 parts of indigofera tinctoria by weight, 4-12 parts of Chinese amphibious knotweed rhizome by weight and 5-15 parts of Chinese mosla herb by weight. The preparation method of the composition comprises: distilling Chinese mosla herb, and collecting the distillate; adding indigofera tinctoria and Chinese amphibious knotweed rhizome in the residue and residual liquid after distillation and decocting for 2-3 times, mixing the decoctive solution and concentrating the solution to viscous liquid, adjusting an alcohol concentration of ethanol to be 60 percent to 70 percent, precipitating, filtrating and concentrating the liquor, adding ethanol and adjusting the alcohol concentration to be 75 percent to 80 percent, sequentially performing precipitation, filtration and concentration of filter liquor, and adding distilled water and refrigerating for precipitation, filtration, and concentration; and blending the distillate of Chinese mosla herb with the collected concentrated solution of indigofera tinctoria and Chinese amphibious knotweed rhizome. The Chinese drug composition can be used for preparation of traditional Chinese veterinary drug to treat blue ear pig disease, porcine circovirus infection, pseudo rabies, piglet pullorum disease of piglet, paratyphoid of piglet, pig erysipelas and edema disease of piglet. Moreover, the Chinese drug composition has the advantages of few side effect and safe and convenient use.

The invention discloses a preparation method and possible application of flagellin FliC from salmonella abortus equi to salmonella abortus equi immunity. Through cloning and connecting a flagellin FliC gene from the salmonella abortus equi to a prokaryotic expression vector pGEX-4T-2, a prokaryotic recombinant of a protein is obtained; the prokaryotic recombinant is transformed into engineering bacteria BL-21, and the protein is subjected to induced expression and purification; the protein has an amino acid sequence in a sequence table 1; the purified FliC recombinant protein has good immunogenicity after being used for the immunization of experimental animals, can overcome the defects of low antibody level and poor safety generated by inactivated vaccines and can be used for preparing subunit vaccines for preventing and treating equine paratyphoid infection and can be used as equine animal vaccine adjuvants, thereby having good development and application prospect.

The invention relates to an application of pineal scale powder in a feed additive for pigs, belonging to an application of pineal scale powder, in particular relating to an application of pineal scale powder in the field of a feed additive for pigs. The pineal scale powder comprises the following raw materials in parts by weight: 78-82 parts of pineal scale powder, 4-6 parts of calcium hydrophosphate, 7-9 parts of zeolite powder, 0.8-1.2 parts of anilazine, 0.8-1.2 arts of bacillus subtillis, 0.5-1.5 parts of bacillus licheniformis, 0.5-1.5 parts of enzyme production probiotics and 2-4 parts of sodium humate. The invention has the beneficial effects that multiple microelement additives can be replaced by the pineal scale powder, so that the feed cost is lowered by 15%, the weight increment is improved by more than 12%, and the fattening time is greatly shortened; furthermore, the fur of the pigs is bright and ruddy, the constitution of the pigs is strong, the meat quality is obviously improved, and the lean meat percentage is improved; and meanwhile, the occurrence of diseases such as swine fever, swine plague, paratyphoid fever, influenza and the like can be reduced.

The invention discloses a process for preparing a typhoid and paratyphoid specific transfer factor oral preparation. The process mainly comprises the following steps of the preparation of immunogen, in vivo immunization of animals, and in vitro immune animal lymphocyte, the preparation of the specific transfer factors of typhoid and paratyphoid, etc. The oral preparation has the functions of transferring cell information, mediating cell immunoreaction, inhibiting specificity and killing salmonella of typhoid and paratyphoid, and also has the function of strengthening nonspecific immunity; the oral preparation has the advantages of no allergic reaction after being taken, safe use and obvious effect, and no drug resistance is generated in a patient who takes the oral preparation; and the product which adopts the oral dosing is not limited by drug taking condition, so that the product is convenient without affecting the biological activity of effective ingredients, is a safe and effective preparation and has good social value and market application prospect.

The invention relates to a traditional Chinese medicine oral liquid for treating chicken paratyphoid fever and a preparation method thereof. The traditional Chinese medicine oral liquid comprises the following ingredients, by weight, 1-5 parts of coke hawthorn, 1-5 parts of honeysuckle flower, 1-5 parts of humifuse euphorbia herb, 1-5 parts of coptis, 1-5 parts of Chinese gall, 1-10 parts of green tangerine peel, 1-5 parts of herba pteridis multifidae and 1-10 parts of licorice. The traditional Chinese medicine oral liquid has effects of antisepsis and anti-inflammation, has advantages of convenient use, low cost, fast effectiveness, little toxic and side effect and almost no residue of veterinary drug, and is an ideal traditional Chinese medicine oral liquid for treating chicken paratyphoid fever.

The present invention discloses an application of typhoid and paratyphoid salmonella in the anti-tumor aspect, which is invented to solve the problems of great side effects and poor effects of the prior art in the treatment of tumors. The present invention provides the application of the typhoid and paratyphoid salmonella in the rapid anti-tumor aspect. Wherein, the tumors are one or more of gastric cancer, lung cancer, liver cancer, tongue squamous cancer, breast cancer, colon cancer, leukemia, brain tumor and sarcoma. The invention makes use of the rapid combination of the typhoid and paratyphoid salmonella with the mononuclear cells after entering into the human body, the strong endotoxin and bacteremia are released and the temperature reaches highly around 40 DEG C to 42 DEG C, so as to affect and inhibit the growth and the life cycle of the tumor cells, furthermore, the large mononuclear cells-macrophages in the reticuloendothelial system are proliferated greatly, thus enhancing the ability of the macrophages in vivo to swallow the cancer cells, so the invention has very significant inhibiting and killing effects of a variety of tumors.

Feed used for preventing swine paratyphoid fever is provided. The feed includes corn, wheat middlings, rice bran, vinasse powder, soybean meal, cotton seed meal, bone meal, imported fish meal, soybean oil, table salt, a premix and a feed additive. Through improving a raw material ratio, contents of protein and other nutrients are increased, nutrition is richer, immunity of pigs is boosted and pigs are more preferred by consumers and safer. The feed comprises the feed additive, and can achieve pest killing and sterilization so that the feed can effectively prevent the swine paratyphoid fever. The feed can improve pig quality, can effectively promote growth of pigs, and can greatly reduce the incidence rate of the swine paratyphoid fever, thus ensuring benefit of farmers.

The invention discloses a compound for treating paratyphoid fever of cat and a preparation method thereof, and aims to provide a compound for treating paratyphoid fever of cat and reduce probability of bacterial drug resistance occurrence and a preparation method thereof. The compound comprises the following components in percentage by weight: 2 to 10 percent of florfenicol, 1 to 5 percent of ofloxacin, 3 to 10 percent of taurine, 2 to 10 percent of sodium chloride, 2 to 10 percent of potassium chloride, 1 to 5 percent of vitamin K3, and the balance of glucosum anhydricum. In the compound, the florfenicol and the ofloxacin serving as antibacterial components can effectively kill salmonella, and is effective to escherichia coli and other bacteria, and combination of the florfenicol and the ofloxacin can reduce the probability of bacteria drug resistance, so that the effect of sterilization and bacteriostasis is reinforced; the taurine has the functions of resisting inflammation, protecting liver and abating fever, and an effect of symptomatic treatment to clinical symptoms caused by paratyphoid fever of cat; the sodium chloride and the potassium chloride can supply electrolyte; the vitamin K3 has an effect of stopping bleeding; and the drugs are combined to treat the paratyphoid fever of cat from various aspects, so that therapeutic errors are reduced.

The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition capable of preventing paratyphoid fever of lambs, and a preparation method of the composition. The traditional Chinese medicine composition is applicable to treatment of diseases of bloody flux, black scour and the like of lambs. The prescription is prepared from the following traditional Chinese medicines: lonicerae flos, radix pulsatillae, cortex phellodendri, pericarpium papaveris, and has the functions of clearing away heat and detoxifying, arresting and inducing astringency, invigorating the spleen for eliminating dampness and harmonizing the stomach and checking diarrhea. The purpose of treating the paratyphoid fever of the lambs can be achieved. The invention provides a preparation method and applications of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the functions of clearing away heat and detoxifying, arresting and inducing astringency, invigorating the spleen for eliminating dampness and harmonizing the stomach and checking diarrhea. By adopting the traditional Chinese medicine and veterinarian therapy and using pure traditional Chinese medicines, the following traditional Chinese medicines are orally taken by the lambs, and the lambs are healed fast without side effects, thus being beneficial to the growth of lambs. The traditional Chinese medicine liquor is simple to blend, and convenient to use, the cost of raw materials is low, no toxic reaction occurs after use, the healing rate is high, and no residues exist, so that the traditional Chinese medicine composition is a desirable drug for treating the paratyphoid fever of the lambs.

The invention provides a feed formula of ewes in the lactation period. Every 1000 parts of the feed comprise, by weight, 390-440 parts of corn, 160-190 parts of silage corn, 200-240 parts of soybean meal, 40-60 parts of palm kernel meal, 90-110 parts of dry clover, 20-40 parts of grass meal, 20-40 parts of beet pulp, 1-3 parts of Herba Leonuri, 1-3 parts of bone meal, 1-3 parts of zeolite powder, 1-2 parts of montmorillonite, 1-2 parts of calcium hydrogen phosphate, 1-3 parts of sodium bicarbonate, 1-2 parts of magnesium oxide, 1-2 parts of zinc sulfate and 2-3 parts of salt. The feed formula has the advantages of reasonable components, complete nutrition, improvement of the palatability of the feed, stimulation of the appetite of the ewes, realization of effective increase of the milk yield due to the addition of proper amounts of medicinal materials, prevention of the paratyphoid fever disease, colibacillosis and other common diseases of lambs in a n ewe intake and lactation manner, realization of full nutrition of the ewes and the lambs, and realization of the healthy growth of the lambs.

The invention discloses a hepatitis-B-paratyphoid-fever-resistant O-SP monoclonal antibody, a hybridoma cell strain and an application. The hybridoma cell strain is named WV-SPB-11, and the collection number is CCTCC NO:C2015228. The monoclonal antibody is secreted through the hybridoma cell strain in the claim 1. The monoclonal antibody is high in purity and antibody titer, and the following experimental requirement is met; the polysaccharide content of hepatitis-A paratyphoid fever O-SPO-SP is measured with the indirect competitive ELISA method built by the monoclonal antibody, the specificity and the sensitivity are high, and particularly, the monoclonal antibody and hepatitis-A paratyphoid fever O-SP polysaccharide, OSP polysaccharide combination and the like are not subjected to a cross reaction.

The invention relates to a kit for separating and identifying salmonella, and a preparation and an application thereof, which are mainly used for solving the technical difficult problems of high omission ratio, complicated identification steps, higher cost and non-intuitive screening result of an existing salmonella separation method. The kit disclosed by the invention comprises general-purpose type non-selective enrichment broth, general-purpose type non-selective enrichment broth which is concentrated by 10 times, selenite sulfonamide green-sulfanilamide enrichment broth, a xylose lysine deoxycholate agar plate, a salmonella enzyme chromogenic agar plate, a salmonella biochemical identification tube, a hydrogen sulfide filter paper strip and an indole filter paper strip, and is characterized by further comprising improved Robert enrichment broth which comprises the following components: 13.58g of magnesium chloride, 7.2g of sodium chloride, 4.5g of papain digestion soybean peptone, 1.26g of KH2PO4, 0.18g of K2HPO4, 36mg of malachite green and 1000ml of distilled water. The kit disclosed by the invention is mainly designed for synchronous separation and identification of salmonella (including typhoid, paratyphoid and non-typhoid and paratyphoid salmonella) in enteric pathogenic bacteria.