Novel biological patch and preparation method thereof

A biological patch, a new type of technology, applied in medical science, surgery, etc., can solve the problems of strong foreign body sensation, poor flexibility, easy to cause infection, etc., and achieve broad application prospects and good thermoplasticity

Inactive Publication Date: 2018-10-16
段降龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, after a long period of clinical use, some disadvantages of the two types of patches have gradually emerged. First, due to poor flexibility, the foreign body sensation after implantation in the human body is strong. Secondly, due to the difference in mechanical compliance between the body and the surrounding tissue, it

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  • Novel biological patch and preparation method thereof
  • Novel biological patch and preparation method thereof
  • Novel biological patch and preparation method thereof

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Embodiment Construction

[0033] In order to make the object, technical solution and advantages of the present invention clearer, various embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings. However, those of ordinary skill in the art can understand that, in each implementation manner of the present invention, many technical details are provided for readers to better understand the present application. However, even without these technical details and various changes and modifications based on the following implementation modes, the technical solutions claimed in this application can also be realized.

[0034] Embodiments of the present invention relate to a preparation method of a novel biological patch, such as figure 1 As shown, the following steps are included in sequence:

[0035] S1, preparation of biological nitrogen-fixing bacteria fermentation culture solution;

[0036] S2, distilling the biological nitrogen-fixing bacteria fer...

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Abstract

The invention relates to the technical field of biological patches, in particular to a novel biological patch and a preparation method thereof. The preparation method comprises the following steps ofpreparing a biological nitrogen-fixation bacterial fermenting culture solution; distilling the biological nitrogen-fixation bacterial fermenting culture solution; extracting PHA (poly-hydroxyalkanoate) by a CHCl3 (chloroform) extracting method in S2; drying the solution after extracting, so as to obtain a PHA powder; analyzing the purity of the PHA by a vapor-phase spectrum method; purifying the object in S4, so as to obtain a collagen-PHA membrane sheet; preparing a polymer solution; soaking the collagen-PHA membrane sheet into the polymer solution, fetching out, relieving pressure and drying, or relieving pressure and drying at high temperature, so as to obtain the biological patch; radiating the obtained biological patch by rays, and sterilizing. The preparation method of the biologicalpatch has the advantages that the preparation method is simple, the yield of the PHA is high, and the purity is high; the medical biological patch prepared from the PHA can be directly absorbed by ahuman body, the rejection reaction of the human body is avoided, and the PHA can be gradually decomposed into CO2 (carbon dioxide) and water in the human body.

Description

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Claims

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Application Information

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Owner 段降龙
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