Aggregation-induced emission based organic fluorescent molecules for uranyl ion detection

Abstract

The invention discloses organic fluorescent molecules which are excellent in and give consideration to the aspects of a detection limit, a detection range and the selectivity. For the organic fluorescent molecules, by utilizing tetraphenylethylene (TPE) groups and recognition groups, through chemical modification, novel aggregation-induced emission (AIE) type organic fluorescent molecules are synthesized, wherein luminophores are groups with the aggregation-induced emission performance, and the recognition groups has high selectivity recognition ability to uranyl ions. Compared with the traditional organic fluorescent probe, the organic fluorescent molecules provided by the invention, the problem of concentration quenching to detection of the uranyl ions does not exist, the detection rangeof the probe can be remarkably improved, the sensitivity and the anti-interference ability can be improved at the same time, and excellence and consideration to the detection limit, the detection range and the selectivity are realized.

Description

technical field [0001] The present invention relates to an organic fluorescent molecule for detection of uranyl ions based on aggregation-induced luminescence. Background technique [0002] With the development of nuclear technology and nuclear industry, the discharge and hazards of radioactive waste are becoming more and more serious. As a heavy metal element, uranium's chemical toxicity can cause necrosis of glomerular cells and atrophy of renal tubules, hepatitis and nervous system, etc. Lesions; As a radionuclide, radiation damage from uranium can cause genetic mutations in humans and cause cancer. Therefore, the detection and safe and effective disposal of radioactive uranium waste is a problem that must be solved. The World Health Organization recommends that the concentration of uranyl ions in drinking water should be lower than 30 μg / L. The determination of uranium content in water will provide an important basis for environmental monitoring and human health risk as...

AI Technical Summary

Problems solved by technology

At present, inorganic acids / salts can achieve lower detection limits, but the selectivity and detection range are not good, which needs to be improved; although biological probes such as DNA enzymes or proteins have good selectivity and low detection limits, but The method is relatively complicated and the cost of living body selection and biological separation is too high, which is not conducive to on-site detection

Organic fluorescent probes are due to the problem of concentration quenching (concentration quenching refers to the high luminous efficiency of organic fluorescent molecules in dilute solutions, but with the increase of the concentration of fluorescent molecules, due to the interaction between molecules, the fluorescence of the system reduction or quenching, that is, the phenomenon of aggregation-caused quenching (ACQ) occurs, in short, the increase in concentration leads to aggregation, thereby quenching the light), so organic fluorescent probes can only be used in dilute solutions Use, so that the detection range will be reduced

In addition, in the practical application of organic fluorescent probes for the detection of uranyl ions, the working environment is basically an aqueous solution, and most organic fluorescent molecules are hydrophobic. Aggregation or precipitation will occur and lead to ACQ effect, which also reduces the detection range of the system to a certain extent (in short, molecular hydrophobicity leads to aggregation, thereby quenching luminescence)

That is, the current organic fluorescent probes cannot achieve the best balance of detection limit, detection range and selectivity.

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