Microneedle patch for moisturizing and preparation method thereof

A micro-needle sticking, moisturizing technology, applied in the field of skin care products, can solve the problems of not really improving the dry and dehydrated state of the skin, unable to fully satisfy, and the effect of hydrating and moisturizing is minimal, so as to improve the dehydrated state of the skin, protect the skin barrier, Simple preparation method

Inactive Publication Date: 2018-11-23
XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main dosage forms of current skin care products are water, lotion, cream, spray, gel and mask. However, due to the obstruction of the stratum corneum of the skin, it is often difficult for the active ingredients that are only coated on the skin surface to enter the dermis, so the moisturizing effect is negligible. , the skin will only appear smooth and supple in a short period of time after using skin care products, but it cannot really improve the dry and dehydrated state of the skin, nor can it fully meet the needs of current consumers

Method used

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  • Microneedle patch for moisturizing and preparation method thereof
  • Microneedle patch for moisturizing and preparation method thereof
  • Microneedle patch for moisturizing and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0032] Embodiments of the present disclosure provide a microneedle patch for moisturizing, such as figure 1 As shown, the microneedle patch includes a main support component and functional components, the main support component forms a base and needles, and the functional components are dispersed in the base and needles. The main support component is a hyaluronic acid solution made of biocompatible hyaluronic acid, and the functional components are composed of the following components by weight percentage: 10% jojoba extract, 5% lavender extract , 15% aloe vera extract, 10% kiwi fruit extract, 5% angelica extract, 10% mung bean extract, 10% urea, 10% ceramide, 8% glycerin, 5% vitamin E, 2% ascorbic acid, 5% allantoin and 5% Tween 60. The needles of the microneedle patch are pyramidal, conical or quasi-conical, the height of the needles is 50 μm, the base diameter is 50 μm, and the distance between the tips of two adjacent needles is 100 μm.

[0033] The preparation method of...

Embodiment 2

[0040] An embodiment of the present disclosure provides a microneedle patch for hydrating and moisturizing, including a main support component and functional components, the main support component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a polylactic acid solution made of biocompatible polylactic acid, and the functional components are composed of the following components by weight percentage: 30% jojoba extract, 3% lavender extract, 25% % aloe extract, 5% kiwi fruit extract, 2% angelica extract, 5% mung bean extract, 15% urea, 5% ceramide, 5% glycerin, 2% vitamin E, 2% ascorbic acid and 1% Tween 40. The needles of the microneedle patch are pyramidal, conical or quasi-conical, the height of the needles is 500 μm, the base diameter is 500 μm, and the distance between the tips of two adjacent needles is 1000 μm.

[0041] The preparation method of the microneedle patch for hydrating and...

Embodiment 3

[0048] An embodiment of the present disclosure provides a microneedle patch for hydrating and moisturizing, including a main support component and functional components, the main support component constitutes a base and needles, and the functional components are dispersed in the base and the needles. The main support component is a maltose solution made of biocompatible maltose, and the functional components are composed of the following components by weight percentage: 20% jojoba extract, 4% lavender extract, 20% Aloe Vera Extract, 8% Kiwi Fruit Extract, 3% Angelica Root Extract, 5% Mung Bean Extract, 15% Urea, 5% Ceramide, 8% Glycerin, 2% Ascorbic Acid, 5% Allantoin, 3% kojic acid and 2% Tween 20. The needles of the microneedle patch are pyramidal, conical or quasi-conical, the height of the needles is 1000 μm, the base diameter is 1000 μm, and the distance between the tips of two adjacent needles is 2000 μm.

[0049] The preparation method of the microneedle patch for hydr...

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Abstract

The embodiment discloses a microneedle patch for moisturizing and a preparation method thereof, and relates to the field of skin care products. The microneedle patch is prepared from a main supportingcomponent and an efficacy component, wherein the main supporting component is prepared from biocompatible degradable materials, the efficacy component is prepared from the following ingredients by weight percent: 10%-30% of jojoba extract, 3%-5% of lavender extract, 15%-25% of aloe extract, 5%-10% of kiwi fruit extract, 2%-5% of radix angelicae dahurioae extract, 5%-10% of mung bean extract, 10%-15% of urea, 5%-10% of ceramide, and 10%-25% of an auxiliary additive. The microneedle patch provided by the invention can effectively pierce the skin and form a channel on the surface of the skin, the efficacy component can be quickly absorbed by the dermis layer to replenish moisture and nutrients as the degradable material of the main supporting component is dissolved rapidly in the skin, thereby fundamentally improving the water shortage state of the skin with high safety.

Description

technical field [0001] The present disclosure relates to the field of skin care products, in particular to a microneedle patch for moisturizing and moisturizing and a preparation method thereof. Background technique [0002] With the progress of society and the development of science and technology, skin care has become a science that people pay more and more attention to in modern times, especially for many women who love beauty, the condition of the skin represents the age. External factors such as ultraviolet radiation, air pollution, seasonal changes, etc., as well as internal factors such as aging, metabolic slowdown, etc., will cause damage to the inner structure of the skin, decrease the ability to maintain moisture, and cause dryness, dullness, roughness, aging and other skin problems. The main dosage forms of current skin care products are water, lotion, cream, spray, gel and mask. However, due to the obstruction of the stratum corneum of the skin, it is often diffi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/9789A61K8/68A61K8/42A61K8/02A61M37/00A61Q19/00
CPCA61M37/0015A61K9/0021A61M2037/0046A61K8/0216A61K8/42A61K8/68A61K8/9789A61K8/9794A61Q19/00
Inventor 陶娟杜虹瑶朱锦涛李钰策张连斌柳佩董励耘李军毛近朱
Owner XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV
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