Method and device for improving resolution by automatic spinning of small nuclear magnetic resonance spectrometer

Abstract

The invention relates to a method for improving a resolution by the automatic spinning of a low-field small nuclear magnetic resonance spectrometer, and a sample tube automatic spinning device used for improving the spectrogram resolution by the automatic spinning of the low-field small nuclear magnetic resonance spectrometer. Under a situation that the magnet and the even field coil of an existing system are not changed, the magnetic field evenness of the low field nuclear magnetic resonance spectrometer is improved. A motor is controlled to indirectly drive a sample tube to stably spin; under different revolving speeds, parameter data related to a magnetic resonance imaging spectrogram resolution is extracted; parameters related to a magnetic resonance experiment and a spectrogram resolution are subjected to contrastive analysis; the corresponding revolving speed under an optimal experiment parameter is obtained by iterative computation to obtain the revolving speed when an effect onovercoming magnetic field unevenness is optimal; then, the system is automatically regulated to operate under the revolving speed in real time, the difference of samples and experiment parameters iseliminated, the magnetic field unevenness is offset to a certain degree, an optimal experiment result is obtained to a maximum degree, a great quantity of comparison works of operation personnel is avoided, and experiment efficiency is greatly improved.

Description

Technical field [0001] The invention relates to the field of research and development of nuclear magnetic resonance instruments, and more specifically, to a method for automatically rotating and enhancing the resolution of a low-field small nuclear magnetic resonance spectrometer, and an automatic rotating and lifting spectrum used for the low-field small nuclear magnetic resonance spectrometer Resolution of the sample tube automatic rotation device. Background technique [0002] In order to improve the sensitivity and resolution of the NMR instrument for detecting the spectrum of the sample under test, it is necessary to have a suitable magnetic field strength and ensure the uniformity of the magnetic field, so as to obtain a high-resolution spectrum of the sample, usually starting from both the instrument hardware design and the experimental method. In hardware design, it mainly relies on the design of the main magnet and the control of the shim coil. The magnet design is achie...

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Problems solved by technology

[0006] However, because the air-controlled rotation of the turbine requires the configuration of an air compressor and a complex gas circuit system, for the NMR equipment with portable small permanent magnets, due to the limitation of the volume, structure and cost of the magnet, the air turbine rotation device cannot be used.

[0007] The sample tube rotation device used in the prior art nuclear magnetic resonance system is manually set by the operator to rotate the sample tube, and the rotation speed under the optimal result cannot be calculated according to the feedback obtained from the experimental results.

Then the rotational speed set in the experiment may not be the rotational speed at the best spectrum resolution that can be achieved, and the noise introduced by the rotational sideband peaks and high rotational instability caused by different rotations also has a great influence on the experimental results

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