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Double-layer bletilla striata dressing

A bletilla striata, double-layer technology, applied in the field of biomedicine, can solve the problems that it is difficult to cover wound healing, easy to stick to gloves, and ineffective, etc., to achieve the effect of rapid healing, good air permeability and soft texture

Active Publication Date: 2018-11-30
WUHAN TEXTILE UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During use, the gloves worn by the doctor during the operation will be stained with blood, which will cause the dressing to dissolve when the bletilla striata dressing is used to treat the patient's wound, which will cause two problems
The first problem is that the dressing is easy to stick to the glove after dissolving, so that the dressing will be uncovered after covering the wound, which is difficult to achieve the purpose of covering the wound to promote healing; the second problem is that part of the dissolved dressing will be wasted and cannot play its role

Method used

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  • Double-layer bletilla striata dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A double-layer bletilla striata dressing. The double-layer bletilla striata dressing is composed of a surface layer 1 and a dressing layer 2. The surface layer 1 is made of a hemostatic material that is insoluble in water, and the dressing layer 2 is made of a porous material of bletilla striata that has good biocompatibility and is easily soluble in water. Composition, the interpenetrating network connection between the surface layer 1 and the dressing layer 2, the establishment of the interpenetrating network is obtained when the dressing layer is formed, that is, the surface layer 1 is tiled on the dressing layer 2 in the solution state, and the surface layer 1 will be partially immersed in the dressing In the layer 2 solution, the surface layer 1 and the dressing layer 2 in this state were frozen and set at -20°C, and then the double-layer bletilla striata dressing was obtained by using freeze-drying technology.

[0031] Surface 1 is fabric.

[0032] The warp and we...

Embodiment 2

[0038] A double-layer bletilla striata dressing, the double-layer bletilla striata dressing is composed of a surface layer 1 and a dressing layer 2, the surface layer 1 is composed of a water-insoluble hemostatic material, and the dressing layer 2 is composed of a porous material of bletilla striata that is good in biocompatibility and easily soluble in water , the interpenetrating network connection between the surface layer 1 and the dressing layer 2, the establishment of the interpenetrating network is obtained when the dressing layer is formed, that is, the surface layer 1 is tiled on the dressing layer 2 in the solution state, and the surface layer 1 will be partially immersed in the dressing layer 2, the surface layer 1 and the dressing layer 2 in this state were frozen and shaped at -50°C, and then the double-layer Bletilla striata dressing was obtained by using freeze-drying technology.

[0039] Surface 1 is fabric.

[0040] The warp and weft density of the fabric is 5...

Embodiment 3

[0046] A double-layer bletilla striata dressing. The double-layer bletilla striata dressing is composed of a surface layer 1 and a dressing layer 2. The surface layer 1 is made of a hemostatic material that is insoluble in water, and the dressing layer 2 is made of a porous material of bletilla striata that has good biocompatibility and is easily soluble in water. Composition, the interpenetrating network connection between the surface layer 1 and the dressing layer 2, the establishment of the interpenetrating network is obtained when the dressing layer is formed, that is, the surface layer 1 is tiled on the dressing layer 2 in the solution state, and the surface layer 1 will be partially immersed in the dressing In the layer 2 solution, the surface layer 1 and the dressing layer 2 in this state were frozen and set at -30°C, and then the double-layer bletilla striata dressing was obtained by using freeze-drying technology.

[0047] The surface layer 1 is a porous material.

[...

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Abstract

The invention relates to double-layer bletilla striata dressing, and belongs to the technical field of biological medicines. The double-layer bletilla striata dressing is composed of a surface layer and a dressing layer, wherein the surface layer is composed of a hemostatic material poorly soluble or insoluble in water, the dressing layer is composed of a bletilla striata porous material having good biocompatibility and being easily soluble in water, for the structural design of interpenetrating network connection between the surface layer and the dressing layer, the integrated forming methodis adopted for realizing physical embedding, and a freeze-drying method is adopted for obtaining a lower dressing layer. The design has the advantages that structure is reasonable, the combination isfirm, the realization is easy, due to the poorly soluble surface layer, the problems that the dressing is difficult to take for use, easily has adhesion, has difficulty in applying, and is large in waste, are solved, due to the porous structure of the easily soluble dressing layer, the dressing rapidly dissolves for forming a protection film, thus the hemostasis efficacy is realized, and the optimal environment for wound healing is created. The dressing is integrally composed of the degradable and absorbable material, and is suitable for being applied to the fields of functional dressing and tissue engineering.

Description

technical field [0001] The invention relates to a double-layer bletilla striata dressing, which belongs to the technical field of biomedicine. Background technique [0002] In the clinical use of surgery, the rapid hemostasis of the wound has an important impact on the postoperative recovery of patients. Bletilla striata is a hemostatic material in traditional Chinese medicine, and its tuber extract, Bletilla striata polysaccharide, has excellent hemostasis and strong antibacterial properties, and is a water-soluble substance. Bletilla striata polysaccharide is widely used in the field of wound dressing because of its excellent astringent hemostasis, antibacterial and anti-inflammatory effects, removing putrefaction and promoting muscle growth, and its biological properties are good, biodegradable, and non-toxic and side effects. The existing Bletilla striata dressing is mainly made into a porous structure to improve its water absorption and then enhance its hemostatic perf...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/42A61L15/28A61L15/32A61L15/64A61L15/44
CPCA61L15/28A61L15/325A61L15/42A61L15/425A61L15/44A61L15/64A61L2300/232A61L2300/412A61L2400/04C08L5/00C08L1/04
Inventor 杨红军王晗李美辰翁雅雪张骞陈欣庄燕徐卫林
Owner WUHAN TEXTILE UNIV
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