A double-layer bletilla striata dressing

A Bletilla striata, double-layer technology, applied in bandages, drug delivery, absorbent pads, etc., can solve the problems of difficult to achieve wound healing, easy adhesion to gloves, and ineffectiveness, and is conducive to rapid healing and good air permeability. , soft texture effect

A Bletilla striata, double-layer technology, applied in bandages, drug delivery, absorbent pads, etc., can solve the problems of difficult to achieve wound healing, easy adhesion to gloves, and ineffectiveness, and is conducive to rapid healing and good air permeability. , soft texture effect

CN108904866BActive Publication Date: 2021-05-28WUHAN TEXTILE UNIV
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  • A double-layer bletilla striata dressing

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A double-layer bletilla striata dressing. The double-layer bletilla striata dressing is composed of a surface layer 1 and a dressing layer 2. The surface layer 1 is made of a hemostatic material that is insoluble in water, and the dressing layer 2 is made of a porous material of bletilla striata that has good biocompatibility and is easily soluble in water. Composition, the interpenetrating network connection between the surface layer 1 and the dressing layer 2, the establishment of the interpenetrating network is obtained when the dressing layer is formed, that is, the surface layer 1 is tiled on the dressing layer 2 in the solution state, and the surface layer 1 will be partially immersed in the dressing In the layer 2 solution, the surface layer 1 and the dressing layer 2 in this state were frozen and set at -20°C, and then the double-layer bletilla striata dressing was obtained by using freeze-drying technology.

[0031] Surface 1 is fabric.

[0032] The warp and we...

Embodiment 2

[0038] A double-layer bletilla striata dressing, the double-layer bletilla striata dressing is composed of a surface layer 1 and a dressing layer 2, the surface layer 1 is composed of a water-insoluble hemostatic material, and the dressing layer 2 is composed of a porous material of bletilla striata that is good in biocompatibility and easily soluble in water , the interpenetrating network connection between the surface layer 1 and the dressing layer 2, the establishment of the interpenetrating network is obtained when the dressing layer is formed, that is, the surface layer 1 is tiled on the dressing layer 2 in the solution state, and the surface layer 1 will be partially immersed in the dressing layer 2, the surface layer 1 and the dressing layer 2 in this state were frozen and shaped at -50°C, and then the double-layer Bletilla striata dressing was obtained by using freeze-drying technology.

[0039] Surface 1 is fabric.

[0040] The warp and weft density of the fabric is 5...

Embodiment 3

[0046] A double-layer bletilla striata dressing. The double-layer bletilla striata dressing is composed of a surface layer 1 and a dressing layer 2. The surface layer 1 is made of a hemostatic material that is insoluble in water, and the dressing layer 2 is made of a porous material of bletilla striata that has good biocompatibility and is easily soluble in water. Composition, the interpenetrating network connection between the surface layer 1 and the dressing layer 2, the establishment of the interpenetrating network is obtained when the dressing layer is formed, that is, the surface layer 1 is tiled on the dressing layer 2 in the solution state, and the surface layer 1 will be partially immersed in the dressing In the layer 2 solution, the surface layer 1 and the dressing layer 2 in this state were frozen and set at -30°C, and then the double-layer bletilla striata dressing was obtained by using freeze-drying technology.

[0047] The surface layer 1 is a porous material.

[...

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Abstract

The invention relates to a double-layer bletilla striata dressing, which belongs to the technical field of biomedicine. The double-layer bletilla striata dressing of the present invention is made up of surface layer and dressing layer, and surface layer is made of insoluble or water-insoluble hemostatic material, and dressing layer is made of Bletilla striata porous material with good biocompatibility, easily soluble in water, between surface layer and dressing layer The structural design of the interpenetrating network connection adopts the physical mosaic of the integral molding method, and the lower dressing layer is obtained by the freeze-drying method. The design structure of the present invention is reasonable, the combination is firm, and it is easy to realize. The problem of large waste, the porous structure of the soluble dressing layer ensures that the dressing quickly dissolves to form a protective film to achieve hemostatic effect and create an optimal environment for wound healing. The whole dressing is composed of degradable absorbing material, which is suitable for application in the field of functional dressing and tissue engineering.

Description

technical field [0001] The invention relates to a double-layer bletilla striata dressing, which belongs to the technical field of biomedicine. Background technique [0002] In the clinical use of surgery, the rapid hemostasis of the wound has an important impact on the postoperative recovery of patients. Bletilla striata is a hemostatic material in traditional Chinese medicine, and its tuber extract, Bletilla striata polysaccharide, has excellent hemostasis and strong antibacterial properties, and is a water-soluble substance. Bletilla striata polysaccharide is widely used in the field of wound dressing because of its excellent astringent hemostasis, antibacterial and anti-inflammatory effects, removing putrefaction and promoting muscle growth, and its biological properties are good, biodegradable, and non-toxic and side effects. The existing Bletilla striata dressing is mainly made into a porous structure to improve its water absorption and then enhance its hemostatic perf...

Claims

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Application Information

Patent Timeline
28 May 2021
Publication
CN108904866B
IPC
A61L15/42; A61L15/28; A61L15/32; A61L15/64; A61L15/44
CPC
A61L15/28; A61L15/325; A61L15/42; A61L15/425; A61L15/44; A61L15/64; A61L2300/232; A61L2300/412
Inventors
杨红军; 王晗