A pharmaceutical composition for treating metabolic diseases, its preparation method and application
A technology for metabolic diseases and compositions, applied in the field of pharmaceutical compositions for treating metabolic diseases and their preparation, can solve problems such as drugs with no specific effect for diabetic nephropathy, and achieve reduction in kidney weight index, convenience in taking, and reduction in protein in urine. The effect of content
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Embodiment 1
[0037] 15 parts of ghost arrow feather, 15 parts of Rehmannia glutinosa, 15 parts of Astragalus, 15 parts of Alisma, 15 parts of Anemarrhena, 10 parts of Cortex Moutan, 12 parts of Dodder, 10 parts of Scrophulariaceae, 3 parts of leeches, 6 parts of rhubarb, extracted with water 3 times , every 1h, add 12 times the amount of water for the first time, add 10 times the amount of water for the second and third times, combine the extracts, concentrate to a relative density of 1.10-1.20, add ethanol to the concentrated clear paste, and adjust the alcohol to 60% ethanol concentration, refrigerated for 12 hours, filtered, recovered ethanol, concentrated to a relative density of 1.15-1.25, dried, and pulverized into extract powder. Add 25 parts of dextrin to the above-mentioned dry extract powder, mix well, and granulate to prepare granules.
Embodiment 2
[0039]15 parts of Guijianyu, 15 parts of Dihuang, 15 parts of Astragalus, 15 parts of Alisma, 15 parts of Anemarrhena, 10 parts of Moutan bark, 12 parts of Cuscuta, 10 parts of Scrophulariaceae, 3 parts of leech, 6 parts of rhubarb, add water to extract 3 times 1 hour each time, add 12 times the amount of water for the first time, add 10 times the amount of water for the second and third times, combine the extracts, concentrate to a relative density of 1.10-1.20, add ethanol to the concentrated clear paste, and adjust the alcohol The ethanol concentration is 60%, refrigerated for 12 hours, filtered, recovered ethanol, concentrated to a relative density of 1.15-1.25, dried, and crushed into extract powder. The above dry extract powder is added with 25 parts of dextrin and 0.5 part of magnesium stearate, mixed evenly, granulated and compressed into tablets to form tablets.
Embodiment 3
[0041] 15 parts of Guijianyu, 15 parts of Dihuang, 15 parts of Astragalus, 15 parts of Alisma, 15 parts of Anemarrhena, 10 parts of Moutan bark, 12 parts of Cuscuta, 10 parts of Scrophulariaceae, 3 parts of leech, 6 parts of rhubarb, add water to extract 3 times 1 hour each time, add 12 times the amount of water for the first time, add 10 times the amount of water for the second and third times, combine the extracts, concentrate to a relative density of 1.10-1.20, add ethanol to the concentrated clear paste, and adjust the alcohol The ethanol concentration is 60%, refrigerated for 12 hours, filtered, recovered ethanol, concentrated to a relative density of 1.15-1.25, dried, and crushed into extract powder. The above dry extract powder is added with 25 parts of dextrin, mixed evenly, granulated, divided into capsules, and then made into capsules.
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