Unlock instant, AI-driven research and patent intelligence for your innovation.

Medicinal composition for treating metabolic diseases as well as preparation method and application of medicinal composition

A technology for metabolic diseases and compositions is applied in the field of pharmaceutical compositions for the treatment of metabolic diseases and their preparation, which can solve the problems of non-specific drugs for diabetic nephropathy and the like, and achieves reduction of kidney weight index, reduction of protein content in urine, and preparation of simple craftsmanship

Active Publication Date: 2019-03-22
YANGTZE RIVER PHARMA GRP JIA NGSU LONGFENGTANG TRADITIONAL CHINESE MEDICINE CO LTD +1
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

30% of American dialysis patients are from diabetic nephropathy, and about 1 / 5 of kidney transplant recipients are diabetic nephropathy patients. Diabetic nephropathy is the main cause of death in diabetes. Currently, there is no effective drug for diabetic nephropathy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicinal composition for treating metabolic diseases as well as preparation method and application of medicinal composition
  • Medicinal composition for treating metabolic diseases as well as preparation method and application of medicinal composition
  • Medicinal composition for treating metabolic diseases as well as preparation method and application of medicinal composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] 15 parts of Guijianyu, 15 parts of Dihuang, 15 parts of Astragalus, 15 parts of Alisma, 15 parts of Anemarrhena, 10 parts of Moutan bark, 12 parts of Cuscuta, 10 parts of Scrophulariaceae, 3 parts of leech, 6 parts of rhubarb, add water to extract 3 times 1 hour each time, add 12 times the amount of water for the first time, add 10 times the amount of water for the second and third times, combine the extracts, concentrate to a relative density of 1.10-1.20, add ethanol to the concentrated clear paste, and adjust the alcohol The ethanol concentration is 60%, refrigerated for 12 hours, filtered, recovered ethanol, concentrated to a relative density of 1.15-1.25, dried, and crushed into extract powder. Add 25 parts of dextrin to the above dry extract powder, mix well, and granulate to make granules.

Embodiment 2

[0039]15 parts of Guijianyu, 15 parts of Dihuang, 15 parts of Astragalus, 15 parts of Alisma, 15 parts of Anemarrhena, 10 parts of Moutan bark, 12 parts of Cuscuta, 10 parts of Scrophulariaceae, 3 parts of leech, 6 parts of rhubarb, add water to extract 3 times 1 hour each time, add 12 times the amount of water for the first time, add 10 times the amount of water for the second and third times, combine the extracts, concentrate to a relative density of 1.10-1.20, add ethanol to the concentrated clear paste, and adjust the alcohol The ethanol concentration is 60%, refrigerated for 12 hours, filtered, recovered ethanol, concentrated to a relative density of 1.15-1.25, dried, and crushed into extract powder. The above dry extract powder is added with 25 parts of dextrin and 0.5 part of magnesium stearate, mixed evenly, granulated and compressed into tablets to form tablets.

Embodiment 3

[0041] 15 parts of Guijianyu, 15 parts of Dihuang, 15 parts of Astragalus, 15 parts of Alisma, 15 parts of Anemarrhena, 10 parts of Moutan bark, 12 parts of Cuscuta, 10 parts of Scrophulariaceae, 3 parts of leech, 6 parts of rhubarb, add water to extract 3 times 1 hour each time, add 12 times the amount of water for the first time, add 10 times the amount of water for the second and third times, combine the extracts, concentrate to a relative density of 1.10-1.20, add ethanol to the concentrated clear paste, and adjust the alcohol The ethanol concentration is 60%, refrigerated for 12 hours, filtered, recovered ethanol, concentrated to a relative density of 1.15-1.25, dried, and crushed into extract powder. The above dry extract powder is added with 25 parts of dextrin, mixed evenly, granulated, divided into capsules, and then made into capsules.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a medicinal composition for treating metabolic diseases. Active ingredients of the medicinal composition are prepared from the following crude drugs in parts by weight: 10 to 20 parts of winged euonymus twig, 10 to 20 parts of radix rehmanniae, 10 to 20 parts of radix astragali, 10 to 20 parts of rhizoma alismatis, 10 to 20 parts of rhizoma anemarrhenae, 5 to 15 parts of cortex moutan, 6 to 18 parts of semen cuscutae, 5 to 15 parts of radix scrophulariae, 1 to 6 parts of hirudo and 2 to 10 parts of radix et rhizoma rhei. In addition, the invention also discloses a preparation method and application of the medicinal composition. The medicinal composition disclosed by the invention has the efficacy of clearing away stagnant heat, supplementing Qi and nourishing Yin; the medicinal composition has the advantages of obvious effects of treating diabetes and nephropathy caused by the diabetes, convenience in administration, smooth and steady effect, accurate curative effect, stable dosage form, controllable quality, no toxic or side effects and capability of meeting the needs of patients.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating metabolic diseases prepared from traditional Chinese medicines and its preparation method and application. Background technique [0002] Diabetic nephropathy is a common microvascular complication of diabetes. During the gradual development of diabetes, it causes kidney damage. Diffuse and nodular glomerulosclerosis can be seen, as well as edema, proteinuria, and hypertension accompanied by these pathological changes. And other clinical manifestations, eventually leading to renal failure. It has been reported that diabetic nephropathy has become the first cause of end-stage renal disease (ESRD). 30% of American dialysis patients are from diabetic nephropathy, and about 1 / 5 of kidney transplant recipients are diabetic nephropathy patients. Diabetic nephropathy is the main cause of death in diabetes. Currently, there ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8964A61P3/00A61P3/10A61P13/12A61K35/62
CPCA61K35/62A61K36/37A61K36/39A61K36/43A61K36/481A61K36/65A61K36/708A61K36/71A61K36/804A61K36/808A61K36/884A61K36/8964A61K2236/331A61P3/00A61P3/10A61P13/12A61K2300/00
Inventor 李伟顾东华曾海松黄旭骅李敏冯瑞红吴革林梁利游慧
Owner YANGTZE RIVER PHARMA GRP JIA NGSU LONGFENGTANG TRADITIONAL CHINESE MEDICINE CO LTD