Phytosterol nano-emulsion capable of losing weight and lowering lipid and preparation method of phytosterol nano-emulsion

A phytosterol and nanoemulsion technology, which is applied in food science, the function and application of food ingredients, etc., can solve the problems of short preparation process, no consideration of the efficacy of free phytosterol, large particle size of the emulsion, etc., and achieves good solubility, Product formula science, the effect of improving lipid metabolism

Pending Publication Date: 2019-04-26
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its advantage is that the emulsion has good stability, but 90% of the phytosterols contained in the emulsion involved in this method are sterol esters, only less than 1% of the free type phytosterols, and the emulsion has not considered the effect of the free type phytosterols
CN108606952A discloses a preparation method of a nanoemulsion of zein loaded with phytosterols. Although the preparation process of this method is short and the efficiency is high, the particle size of the obtained emulsion is above 350nm, and the particle size of the emulsion is relatively large

Method used

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  • Phytosterol nano-emulsion capable of losing weight and lowering lipid and preparation method of phytosterol nano-emulsion
  • Phytosterol nano-emulsion capable of losing weight and lowering lipid and preparation method of phytosterol nano-emulsion
  • Phytosterol nano-emulsion capable of losing weight and lowering lipid and preparation method of phytosterol nano-emulsion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The formula and preparation method thereof of a weight-reducing phytosterol nanoemulsion is characterized in that each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0036]

[0037] Weigh 5% sodium caseinate and dissolve it in distilled water, and keep stirring at room temperature for 1 hour to make it fully hydrated; weigh 0.5% 4,4'-methyl sterol and mix and dissolve 5% long-chain triglyceride, Then mix it into the protein water solution, add 0.1% vitamin C and 0.1% sodium chloride, and cut it for 2 minutes at 18000rpm with a high-speed disperser to make a primary coarse emulsion; 1. Homogenize under the condition that the secondary pressure is 40MPa, stir and cool down after homogenization, use Nano Brook Omni multi-angle particle size for particle size analysis, the average particle size of the colloidal dispersion is 158.5nm, and it is monodisperse spherical (PDI=0.156) , the emulsion potential is -...

Embodiment 2

[0039] The formula and preparation method thereof of a weight-reducing phytosterol nanoemulsion is characterized in that each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0040]

[0041]Weigh 5% whey protein isolate and dissolve in distilled water, keep stirring at room temperature for 3 hours to make it fully hydrated; weigh 1% of the quality of methyl sterol, 4-methyl sterol and 4,4'-dimethyl sterol Mix and dissolve the mixture with 10% olive oil at a ratio of 1:1:2, then mix it into the protein water solution, add 0.3% vitamin E and 0.2% potassium chloride, and use a high-speed disperser to shear at 10,000rpm for 10min. Make the primary coarse emulsion; use a high-pressure homogenizer to homogenize under the condition of the primary pressure of 135MPa and the secondary pressure of 50MPa, stir and cool down after homogenization, use Nano Brook Omni multi-angle particle size for particle size analysis, collo...

Embodiment 3

[0043] The formula and preparation method thereof of a weight-reducing phytosterol nanoemulsion is characterized in that each raw material is calculated by weight percentage, and its raw material composition and content are as follows:

[0044]

[0045]

[0046] Weigh 15% pea protein and dissolve it in distilled water, keep stirring at room temperature for 6 hours to make it fully hydrated; weigh 4% of the mixture of methyl-free sterol and 4,4'-dimethyl sterol with a mass ratio of 1:2 and mix with 25 After % rice oil is mixed and dissolved, then mixed into the protein aqueous solution, after adding 0.6% tea polyphenols and 0.5% sodium chloride, shear 5min under the condition of 18000rpm with a high-speed disperser to make primary coarse emulsion; The quality machine is homogenized under the condition of primary pressure of 85MPa and secondary pressure of 60MPa. After homogenization, it is stirred and cooled down. The particle size analysis is carried out by using Nano Bro...

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Abstract

The invention discloses phytosterol nano-emulsion capable of losing weight and lowering lipid and a preparation method of the phytosterol nano-emulsion. The phytosterol nano-emulsion is prepared fromthe following raw materials in percentage by mass: 0.5 to 4 percent of phytosterol, 5 to 25 percent of nutritional oil, 5 to 15 percent of an emulsifier, 0.1 to 0.6 percent of an antioxidant, 0.1 to 0.5 percent of an inorganic additive and the balance of water which is aaded until the content is 100 percent. According to the phytosterol nano-emulsion disclosed by the invention, the ratio of threetypes of phytosterols are reasonably adjusted, and 4-demethlyate sterol and 4,4'-dimethyl sterol have a sufficient synergetic effect to alleviate the obesity; meanwhile, a cholesterol lowering effectand a mechanism of adjusting an endogenous cannabinoids system are used simultaneously to realize the effect of cooperatively lowering the lipid. The phytosterol nano-emulsion prepared by the invention can be directly applied to functional foods, medicines and the like; the dosage of lipid-lowering Western medicines is reduced and the lipid-lowering effect is remarkable; other complications can beobviously alleviated or eliminated.

Description

technical field [0001] The invention belongs to the technical field of health food processing, and in particular relates to a slimming and lipid-lowering phytosterol nanoemulsion and a preparation method thereof. Background technique [0002] Nowadays, chronic diseases represented by cardiovascular and cerebrovascular diseases, malignant tumors, chronic respiratory diseases and diabetes have become important public problems that threaten human health. Phytosterols are of great significance for lowering blood cholesterol levels, controlling body weight, and reducing the occurrence of cardiovascular diseases However, since phytosterols are insoluble in water, it is difficult to directly add them to water-based foods. [0003] CN1599560A discloses an oil-in-water emulsion containing phytosterols. The advantage is that the emulsion has good stability, but 90% of the phytosterols contained in the emulsion involved in the method are sterol esters, and only less than 1% of the fre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A23L33/12A23L33/15A23L33/16A23L33/185A23L33/19
CPCA23V2002/00A23L33/105A23L33/12A23L33/15A23L33/16A23L33/185A23L33/19A23V2200/3262A23V2250/21368A23V2250/708A23V2250/712A23V2250/211A23V2250/214
Inventor 常明张涛王兴国金青哲刘睿杰黄健花
Owner JIANGNAN UNIV
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