Antibacterial, anti-inflammatory, sebum-reducing, keratin peeling and skin calming composition

An anti-inflammatory, sebum technology, applied in the direction of anti-inflammatory agents, skin diseases, antibacterial drugs, etc., can solve problems such as irritated acne skin

Inactive Publication Date: 2019-06-18
SKINCURE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most natural calming ingredients are oil-soluble and subject to the following restrictions. Compared with solubilized dosage forms such as skin care water and toner, it is more suitable for emulsified products
Solubilized products can be produced, but as the content of solubilizers increases, there is a concern that sensitive acne-prone skin will be irritated, and essential oils may cause discomfort to some people due to their strong fragrance

Method used

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  • Antibacterial, anti-inflammatory, sebum-reducing, keratin peeling and skin calming composition
  • Antibacterial, anti-inflammatory, sebum-reducing, keratin peeling and skin calming composition
  • Antibacterial, anti-inflammatory, sebum-reducing, keratin peeling and skin calming composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] selection of natural extract material and composition ratio establishment

[0083] 1-1. Preparation of natural extract

[0084] Wash onion (whole herb), lacquer (leaf), medlar (fruit), licorice (whole herb), loquat (leaf), rice bran (hull), white willow (bark) as natural products shown in Table 1 below . After removing foreign substances and impurities, dry in the shade at 20 to 35° C. and then pulverize so that the particle size becomes 1 mm or less.

[0085] 100 g of each obtained powder was immersed in 10 L of 70% ethanol, and ultrasonic extraction was performed twice every 24 hours. Thereafter, the obtained extract was filtered with filter paper (Advantes, No. 2), concentrated under reduced pressure, and each extract was prepared. After the rice bran extract was prepared by the above method, it was hydrolyzed by enzymes, filtered again with filter paper (Advantes, No. 2), and concentrated under reduced pressure to prepare rice bran hydrolyzate.

[0086] 1-2. An...

Embodiment 2

[0098] composite mixture of the present invention is prepared

[0099] Through the composite composition of the selected extracts and nicotinamide, it is tested whether the composite function of skin calming effect can be exhibited and the synergistic effect of efficacy can be presented at the same time. Specifically, the compound extracts of orange peel, onion, medlar, licorice, white willow leaves and spinach; rice bran hydrolyzate; figure 1 The preparation procedure shown, a complex mixture (AquMix) was prepared. For convenience, the above composite mixture is named AquMix.

[0100] Table 2

[0101]

Embodiment 3

[0117] preparation of skin external preparation containing complex mixture (AquMix)

[0118] In order to confirm whether the composite mixture (AquMix) of the present invention is safe to human skin, after preparing the skin external preparation containing the composite mixture (AquMix) according to the composition and content of the following table 1, carry out skin stability and clinical efficacy test. First, purified water, glycerin, and butylene glycol were mixed and dissolved at 70°C (water portion), and the remaining components other than the above three components and trimethanolamine were dissolved at 70°C (oil portion). The above-mentioned oil part was added to the water part, and stirred with a high-speed stirrer (Tokushu Kika Co., Ltd., Japan) to perform primary emulsification. Wherein after finally adding trimethanolamine, after removing the air bubbles generated in the above mixed solution, cooling at room temperature to prepare the skin external preparation.

...

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PUM

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Abstract

The invention relates to an antibacterial, anti-inflammatory, sebum-reducing, keratin peeling and skin calming composition comprising a composite mixture formed by mixing a composite extractive composed of orange peel, onion, matrimony vine, licorice, white willow leaf and spinach, rice bran hydrolysate and nicotinamide and use thereof. The composition of the present invention exhibits the effectsof inhibiting the growth of microorganisms associated with acne diseases, regulating the division of sebum cells and sebum secretion, not only improving the keratin peeling of hyperkeratosis of hairfollicles, but also reducing the oil content, the sebum secretion value, and the number of closed acne and open acne of acne skin. Further, since the composition comprising the composite mixture hasalmost no toxicity and side effects, it can be safely used for a long period of time, and can be safely applied to a cosmetic or skin external preparation composition. In particular, since it is water-soluble, it does not require a co-solvent, and can also be applied to development of transparent products such as transparent skin care water.

Description

technical field [0001] The present invention relates to antibacterial, anti-inflammation, sebum reduction, keratin exfoliation and skin calming compositions, and more specifically relates to a compound extract comprising orange peel, onion, medlar, licorice, white willow leaves and spinach, rice bran hydrolyzate and tobacco A complex mixture of Niacinamides, which is safe when applied to the human body and has excellent antibacterial, anti-inflammation, sebum reduction, keratin exfoliation and skin calming effects, and its use. Background technique [0002] Due to the serious air pollution caused by the recent sharp increase in smog and yellow sand, the resulting increase in ultraviolet index, abnormal hormone tendency and external pressure, the skin health of modern people is gradually threatened. Sensitive skin types increase as the skin is constantly exposed to harmful factors such as chemicals and ultraviolet rays, and the immune response to irritation activates the infl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/9789A61K8/67A61Q19/00A61Q17/00A61K36/899A61P31/02A61P31/04A61P29/00A61P17/08A61P17/12A61P17/00A61P17/10A61K31/455
CPCA61K8/675A61K8/97A61K36/484A61K36/752A61K36/815A61K36/8962A61K2300/00A61K2800/28A61K2800/59A61Q17/005A61Q19/00
Inventor 赵伸桓金名玉
Owner SKINCURE
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