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Wound depth repairing regenerative dressing formula and preparation method thereof

A technology of repair and regeneration, formula, applied in the fields of medical science, absorption pads, bandages, etc., to achieve the effect of accelerating skin regeneration, realizing cell proliferation, and inhibiting the formation of scars

Inactive Publication Date: 2019-07-19
BEIJING BEST LIFE REGENERATIVE MEDICINE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after the dressing containing bioactive glass is applied to the wound surface, when the bioactive glass particles contact with the liquid, a rapid reaction occurs on the surface, causing a rapid increase in local pH, and its pH value can reach 11, forming a strong alkalinity, which has a certain Cytotoxicity, many patients feel irritation and instant pain, which brings certain pain to patients

Method used

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  • Wound depth repairing regenerative dressing formula and preparation method thereof
  • Wound depth repairing regenerative dressing formula and preparation method thereof
  • Wound depth repairing regenerative dressing formula and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A wound depth repair regenerative dressing formulation, comprising the following formulations in parts by weight:

[0021] 10 parts of bioactive regenerated silicon powder 5 parts of medical grade sodium hyaluronate

[0022] 5 parts carboxymethyl chitosan 5 parts medical grade vitamin E oil

[0023] 55 parts of medical white vaseline 10 parts of medical liquid paraffin

[0024] 10 parts of medical lanolin and 1 part of polyethylene glycol 4000.

[0025] The preparation method of the deep wound repair regenerative dressing formula of the present embodiment comprises:

[0026] First, 55 parts of medical white vaseline, 10 parts of medical liquid paraffin, and 10 parts of medical lanolin were prepared according to the ratio and put into a container, melted at 80°C, stirred for 5-20 minutes, and mixed uniformly to prepare A solution;

[0027] Weigh 1 part of polyethylene glycol 4000 and add it to solution A, stir at 80°C for 40-60 minutes until uniformly prepared into so...

Embodiment 2

[0049] A wound depth repair regenerative dressing formulation, comprising the following formulations in parts by weight:

[0050] 20 parts of bioactive regenerated silicon powder 6 parts of medical grade sodium hyaluronate

[0051] 6 parts carboxymethyl chitosan 6 parts medical grade vitamin E oil

[0052] 46 parts of medical white vaseline 5 parts of medical liquid paraffin

[0053] 5 parts of medical lanolin 6 parts of polyethylene glycol 4000

[0054] The preparation method of the deep wound repair regenerative dressing formula of the present embodiment comprises:

[0055] First, 46 parts of medical white petrolatum, 5 parts of medical liquid paraffin, and 5 parts of medical lanolin were prepared according to the ratio and put into a container, melted at 80 ° C, stirred for 5-20 minutes, and prepared into A solution until uniformly mixed;

[0056] Weigh 6 parts of polyethylene glycol 4000 and add to solution A, stir at 80°C for 40-60min until uniformly prepared into solu...

Embodiment 3

[0072] A wound depth repair regenerative dressing formulation, comprising the following formulations in parts by weight:

[0073] 30 parts of bioactive regenerated silicon powder 6 parts of medical grade sodium hyaluronate

[0074] 2 parts carboxymethyl chitosan 2 parts medical grade vitamin E oil

[0075] 50 parts of medical white vaseline 2 parts of medical liquid paraffin

[0076] 2 parts of medical lanolin 6 parts of polyethylene glycol 4000.

[0077] The preparation method of the deep wound repair regenerative dressing formula of the present embodiment comprises:

[0078] First, 50 parts of medical white vaseline, 2 parts of medical liquid paraffin, and 2 parts of medical lanolin were prepared according to the ratio and put into a container, melted at 80 ° C, stirred for 5-20 minutes, and prepared into A solution until uniformly mixed;

[0079] Weigh 6 parts of polyethylene glycol 4000 and add to solution A, stir at 80°C for 40-60min until uniformly prepared into solut...

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Abstract

The invention discloses a wound depth repairing regenerative dressing formula and a preparation method thereof. The formula includes: bioactive regenerated silicon powder, medical grade sodium hyaluronate, carboxymethyl chitosan, medical vitamin E oil, medical white vaseline, medical liquid paraffin, medical lanolin and polyethylene glycol 4000. The remarkable effects of the formula is that the implementation is simple, and the above formula adopts a specific ratio, which can realize ion exchange in cells and form a three-dimensional network structure consistent with the original skin, and realizes the ordered growth of a new tissue fiber layer, the regeneration of capillaries and hair follicles, the regeneration repairing of wound endogenous tissue and the inhibition of scar formation. The formula is fused with a specific proportion while preparation is carried out, the operation is simple, the wound can be quickly healed, and the regeneration repairing of wound endogenous tissue canbe realized.

Description

technical field [0001] The invention relates to a formula and a preparation method of a regeneration dressing for deep wound repair. Background technique [0002] At present, most of the medical dressings are dressings containing bioactive glass. Bioactive glass has good bioactivity and biocompatibility, can activate the expression of genes related to wound healing, promote the proliferation and differentiation of fibroblasts, accelerate the formation of blood vessels, promote the growth of granulation tissue, and promote the formation of hard and soft tissues. Repair and regeneration, promote wound healing. However, after the dressing containing bioactive glass is applied to the wound surface, when the bioactive glass particles contact with the liquid, a rapid reaction occurs on the surface, causing a rapid increase in local pH, and its pH value can reach 11, forming a strong alkalinity, which has a certain Cytotoxicity, many patients feel stimulation and instant pain, wh...

Claims

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Application Information

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IPC IPC(8): A61L15/18A61L15/62A61L15/44A61L15/20A61L15/28A61L15/34A61L15/26
CPCA61L15/18A61L15/20A61L15/26A61L15/28A61L15/34A61L15/44A61L15/62A61L2300/10A61L2300/112A61L2300/41A61L2300/412A61L2300/418A61L2300/45C08L5/08C08L71/02
Inventor 高玉森胡方刘小畅
Owner BEIJING BEST LIFE REGENERATIVE MEDICINE TECH CO LTD
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